UY26752A1 - Combinaciones de carboxialquilater ) -inhibidor de acat - Google Patents

Combinaciones de carboxialquilater ) -inhibidor de acat

Info

Publication number
UY26752A1
UY26752A1 UY26752A UY26752A UY26752A1 UY 26752 A1 UY26752 A1 UY 26752A1 UY 26752 A UY26752 A UY 26752A UY 26752 A UY26752 A UY 26752A UY 26752 A1 UY26752 A1 UY 26752A1
Authority
UY
Uruguay
Prior art keywords
acat inhibitor
carboxial
alkylater
combinations
formula
Prior art date
Application number
UY26752A
Other languages
English (en)
Inventor
Auerbach
Bruce Jeffrey Y Zobel
Donna Lee
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of UY26752A1 publication Critical patent/UY26752A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención es una composición farmacéutica que comprende un carboxialquiléter que reduce triglicéridos y LDL y eleva el HDL y un inhibidor de ACAT que mejora la dislipidemia en mamíferos, dicha composición es útil para tratar la dislipidemia y síndromes isquémicos y para prevenir o retardar el comienzo de ataques cardíacos. Los carboxialquiéteres tienen la fórmula en donde Y1 e Y2 incluyen COOH, R1, R2, R3 y R4 pueden ser alquilo, y n y m son números enteros de 2 a 9; y los inhibidores de ACAT tienen la fórmula en donde R es hidrógeno , X es O, R1 y R2 son fenilo sustituido, e Y es alquileno.
UY26752A 2000-06-07 2001-06-05 Combinaciones de carboxialquilater ) -inhibidor de acat UY26752A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21005600P 2000-06-07 2000-06-07

Publications (1)

Publication Number Publication Date
UY26752A1 true UY26752A1 (es) 2001-07-31

Family

ID=22781424

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26752A UY26752A1 (es) 2000-06-07 2001-06-05 Combinaciones de carboxialquilater ) -inhibidor de acat

Country Status (14)

Country Link
EP (1) EP1292363A2 (es)
JP (1) JP2003535125A (es)
AR (1) AR034255A1 (es)
AU (1) AU2001263003A1 (es)
BR (1) BR0111428A (es)
CA (1) CA2413906A1 (es)
GT (1) GT200100106A (es)
MX (1) MXPA02010762A (es)
PA (1) PA8518601A1 (es)
PE (1) PE20020265A1 (es)
SV (1) SV2002000466A (es)
TN (1) TNSN01085A1 (es)
UY (1) UY26752A1 (es)
WO (1) WO2001093845A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7387236B2 (en) 2001-10-09 2008-06-17 Delaware Capital Formation, Inc. Dispensing of currency

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69833971T2 (de) * 1998-01-28 2006-11-02 Warner-Lambert Co. Llc Verfahren zur behandlung der alzheimerschen krankheit

Also Published As

Publication number Publication date
JP2003535125A (ja) 2003-11-25
GT200100106A (es) 2002-05-20
BR0111428A (pt) 2003-06-10
WO2001093845A3 (en) 2002-10-10
TNSN01085A1 (en) 2005-11-10
AR034255A1 (es) 2004-02-18
EP1292363A2 (en) 2003-03-19
PA8518601A1 (es) 2002-07-30
AU2001263003A1 (en) 2001-12-17
CA2413906A1 (en) 2001-12-13
WO2001093845A2 (en) 2001-12-13
SV2002000466A (es) 2002-04-03
PE20020265A1 (es) 2002-04-19
MXPA02010762A (es) 2003-03-10

Similar Documents

Publication Publication Date Title
DK1299348T3 (da) Forbindelser og sammensætninger til levering af aktive midler
UY27465A1 (es) Métodos y composiciones para tratar flavivirus y pestivirus con 4' modificaciones nucleosides
AR072578A1 (es) Compuestos de piperidina puenteada tipo quinoxalina sustituida y los usos de los mismos
ECSP024382A (es) Inhibidores de proteasa de serina
UY25322A1 (es) Compuestos de tiourea y benzamida,composiciones y metodos para tratar y prevenir enfermedades inflamatorias y aterosclerosis
DK1257550T3 (da) Blodplade-ADP-receptor-inhibitor
BR9904162A (pt) 4-carboxiamino-2-metil-1,2,3,4-tetra-hidroquinolinas aneladas
NO20031001L (no) Polyarylkarboksamider nyttige som lipidsenkende midler
SE0000540D0 (sv) New compounds
BR0213981A (pt) Fotoiniciadores difuncionais
EA200201175A1 (ru) Применение ингибиторов il-18 для лечения и/или предотвращения атеросклероза
EA200300836A1 (ru) Производные фталазинон-пиперидина в качестве ингибиторов pde4
EP1163208A4 (en) CASPASE INHIBITORS AND THEIR USE
AR058266A1 (es) Derivados espirociclicos inhibidores de pde7 y su aplicacion terapeutica
EA200400734A1 (ru) Способ и композиция для потенциирования действия опиатного анальгетика
ES2421948T3 (es) Compuestos y composiciones para suministrar agentes activos
IS2287B (is) Nýjar afleiður og hliðstæður af galantamíni
PE20230251A1 (es) Terapia de combinacion que comprende un inhibidor de alk2 y un inhibidor de jak2
SE0003476D0 (sv) Compounds
UY26752A1 (es) Combinaciones de carboxialquilater ) -inhibidor de acat
DOP2001000184A (es) Combinaciones de carboxialquileter-inhibidor de acat
PT1292290E (pt) Composicoes farmaceuticas que compreendem derivados de acriloil-distamicina e inibidores de topoisomerase 1 e ii
EA200300978A1 (ru) Ингибирование поглощения моноамина
ECSP034422A (es) Inhibidores de la trombina que contiene un grupo de aminoisoquinolina
AR037140A1 (es) Un compuesto de aminopirrol, su utilizacion, un procedimiento para producirlo y una composicion que lo comprende

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20140627