ES2143206T3 - Procedimiento para la produccion de acido lipoico. - Google Patents

Procedimiento para la produccion de acido lipoico.

Info

Publication number
ES2143206T3
ES2143206T3 ES96919924T ES96919924T ES2143206T3 ES 2143206 T3 ES2143206 T3 ES 2143206T3 ES 96919924 T ES96919924 T ES 96919924T ES 96919924 T ES96919924 T ES 96919924T ES 2143206 T3 ES2143206 T3 ES 2143206T3
Authority
ES
Spain
Prior art keywords
pct
procedure
production
lipoic acid
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96919924T
Other languages
English (en)
Inventor
Brian Michael Adger
Raymond Chriroscience Mccague
Stanley Michael Depart Roberts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2143206T3 publication Critical patent/ES2143206T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE ACIDO LIPOICO (ACIDO TIOCTICO), O UN DERIVADO DEL MISMO, ES UNO EN EL QUE UNA CICLOHEXANONA SUSTITUIDA EN 2 SE TRANSFORMA EN UNA REACCION DE OXIDACION EN UNA LACTONA QUE POSEE LA FORMULA (I), EN LA QUE X ES UN SUSTITUYENTE HETEROATOMO.
ES96919924T 1995-05-30 1996-05-30 Procedimiento para la produccion de acido lipoico. Expired - Lifetime ES2143206T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9510858.5A GB9510858D0 (en) 1995-05-30 1995-05-30 Process for preparing lipoic acid

Publications (1)

Publication Number Publication Date
ES2143206T3 true ES2143206T3 (es) 2000-05-01

Family

ID=10775210

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96919924T Expired - Lifetime ES2143206T3 (es) 1995-05-30 1996-05-30 Procedimiento para la produccion de acido lipoico.

Country Status (12)

Country Link
US (1) US6140512A (es)
EP (1) EP0835251B1 (es)
JP (1) JP3856830B2 (es)
AT (1) ATE189219T1 (es)
AU (1) AU5828896A (es)
DE (1) DE69606411T2 (es)
DK (1) DK0835251T3 (es)
ES (1) ES2143206T3 (es)
GB (1) GB9510858D0 (es)
GR (1) GR3033198T3 (es)
PT (1) PT835251E (es)
WO (1) WO1996038437A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021208A1 (en) 1999-09-23 2001-03-29 Juvenon Corporation Nutritional supplement for increased energy and stamina
US6562869B1 (en) 1999-09-23 2003-05-13 Juvenon, Inc. Nutritional supplement for increased energy and stamina
CA2418155A1 (en) * 2000-07-18 2002-01-24 National Research Council Of Canada Cloning, sequencing and expression of a comamonas cyclopentanone 1,2-monooxygenase-encoding gene in escherichia coli
DE10038147A1 (de) * 2000-08-04 2002-02-14 Sued Chemie Ag Propfpolymere oder -copolymere
IT1319196B1 (it) * 2000-10-10 2003-09-26 Laboratorio Chimico Int Spa Sintesi dell'acido r(+)alfa-lipoico.
IT1319194B1 (it) * 2000-10-10 2003-09-26 Laboratorio Chimico Int Spa Processo per la produzione dell'acido tiottico racemo.
US20040137551A1 (en) * 2003-01-13 2004-07-15 Markovic Nenad S. Cervical acid phosphatase - papanicolaou (CAP-PAP) test kit, method and accesories, processes for producing and using the same
US20090078581A1 (en) * 2007-09-24 2009-03-26 Applied Intellectual Capital Configurations and Methods of Reduction of Lipoic Acid
CN115772155B (zh) * 2021-09-07 2023-10-24 山东新时代药业有限公司 一种α-硫辛酸中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2114984T3 (es) * 1992-09-08 1998-06-16 Basf Ag Procedimiento mejorado para la obtencion de acido r/s-gamma-lipoico o acido r/s-alfa-lipoico.
DE4229914A1 (de) * 1992-09-08 1994-03-10 Basf Ag Verbessertes Verfahren zur Herstellung von R/S-Ï-Liponsäure oder R/S-â-Liponsäure

Also Published As

Publication number Publication date
GB9510858D0 (en) 1995-07-26
WO1996038437A1 (en) 1996-12-05
ATE189219T1 (de) 2000-02-15
EP0835251B1 (en) 2000-01-26
DK0835251T3 (da) 2000-06-26
GR3033198T3 (en) 2000-08-31
EP0835251A1 (en) 1998-04-15
PT835251E (pt) 2000-06-30
AU5828896A (en) 1996-12-18
DE69606411D1 (de) 2000-03-02
JP3856830B2 (ja) 2006-12-13
JPH11506443A (ja) 1999-06-08
DE69606411T2 (de) 2000-06-21
US6140512A (en) 2000-10-31

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