PE20011374A1 - 4-amino-azepan-3-ona como inhibidores de proteasas - Google Patents
4-amino-azepan-3-ona como inhibidores de proteasasInfo
- Publication number
- PE20011374A1 PE20011374A1 PE2001000566A PE2001000566A PE20011374A1 PE 20011374 A1 PE20011374 A1 PE 20011374A1 PE 2001000566 A PE2001000566 A PE 2001000566A PE 2001000566 A PE2001000566 A PE 2001000566A PE 20011374 A1 PE20011374 A1 PE 20011374A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- azepan
- amino
- ona
- het
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59384500A | 2000-06-14 | 2000-06-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20011374A1 true PE20011374A1 (es) | 2002-04-07 |
Family
ID=24376433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2001000566A PE20011374A1 (es) | 2000-06-14 | 2001-06-14 | 4-amino-azepan-3-ona como inhibidores de proteasas |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1307204A4 (sk) |
JP (1) | JP2004503502A (sk) |
KR (1) | KR20030008220A (sk) |
CN (1) | CN1444481A (sk) |
AP (1) | AP2002002671A0 (sk) |
AR (1) | AR032622A1 (sk) |
AU (1) | AU2001268407A1 (sk) |
BG (1) | BG107327A (sk) |
BR (1) | BR0111693A (sk) |
CA (1) | CA2412353A1 (sk) |
CZ (1) | CZ20024086A3 (sk) |
EA (1) | EA200300018A1 (sk) |
EC (1) | ECSP024388A (sk) |
HU (1) | HUP0301231A2 (sk) |
IL (1) | IL153421A0 (sk) |
MA (1) | MA25758A1 (sk) |
MX (1) | MXPA02012442A (sk) |
NO (1) | NO20025786L (sk) |
NZ (1) | NZ522965A (sk) |
OA (1) | OA12288A (sk) |
PE (1) | PE20011374A1 (sk) |
PL (1) | PL360508A1 (sk) |
SK (1) | SK17592002A3 (sk) |
WO (1) | WO2001095911A1 (sk) |
ZA (1) | ZA200209808B (sk) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001034159A1 (en) * | 1999-11-10 | 2001-05-17 | Smithkline Beecham Corporation | Protease inhibitors |
WO2001034158A1 (en) * | 1999-11-10 | 2001-05-17 | Smithkline Beecham Corporation | Protease inhibitors |
IL155997A0 (en) * | 2000-11-22 | 2003-12-23 | Smithkline Beecham Corp | Protease inhibitors |
US7709510B2 (en) | 2001-02-20 | 2010-05-04 | Chugai Seiyaku Kabushiki Kaisha | Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
JP4155351B2 (ja) | 2001-02-20 | 2008-09-24 | 中外製薬株式会社 | 代謝調節剤として有用なマロニル−CoA脱炭酸酵素阻害剤としてのアゾール |
AU2002342682A1 (en) * | 2001-05-17 | 2002-11-25 | Smithkline Beecham Corporation | Protease inhibitors |
DE602004016530D1 (de) | 2003-08-01 | 2008-10-23 | Chugai Pharmaceutical Co Ltd | Azol-verbindungen auf cyanoguanidin-basis als malonyl-coa decarboxylase-hemmer |
ATE400272T1 (de) | 2003-08-01 | 2008-07-15 | Chugai Pharmaceutical Co Ltd | Piperidin-verbindungen als malonyl-coa decarboxylase-hemmer |
ATE487475T1 (de) | 2003-08-01 | 2010-11-15 | Chugai Pharmaceutical Co Ltd | Heterocyclische verbindungen als nützliche malonyl-coa decarboxylase-hemmer |
EP2240491B1 (en) | 2008-01-09 | 2015-07-15 | Amura Therapeutics Limited | TETRAHYDROFURO(2,3-b)PYRROL-3-ONE DERIVATIVES AS INHIBITORS OF CYSTEINE PROTEINASES |
CN103275070A (zh) * | 2013-05-10 | 2013-09-04 | 郑彪 | 调节单核细胞增殖的四环化合物及其应用 |
US9427441B2 (en) | 2014-02-19 | 2016-08-30 | Indiana University Research And Technology Corporation | Targeting primary cilia to treat glaucoma |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DZ2285A1 (fr) * | 1996-08-08 | 2002-12-25 | Smithkline Beecham Corp | Inhibiteurs de protéase de la cystéine. |
BR9916488A (pt) * | 1998-12-23 | 2001-10-09 | Smithkline Beecham Corp | Inibidores de protease |
JP2003513956A (ja) * | 1999-11-10 | 2003-04-15 | スミスクライン・ビーチャム・コーポレイション | プロテアーゼ阻害剤 |
WO2001034158A1 (en) * | 1999-11-10 | 2001-05-17 | Smithkline Beecham Corporation | Protease inhibitors |
JP2004509083A (ja) * | 2000-09-01 | 2004-03-25 | スミスクライン・ビーチャム・コーポレイション | 治療方法 |
IL155997A0 (en) * | 2000-11-22 | 2003-12-23 | Smithkline Beecham Corp | Protease inhibitors |
AU2002342682A1 (en) * | 2001-05-17 | 2002-11-25 | Smithkline Beecham Corporation | Protease inhibitors |
-
2001
- 2001-06-14 HU HU0301231A patent/HUP0301231A2/hu unknown
- 2001-06-14 PE PE2001000566A patent/PE20011374A1/es not_active Application Discontinuation
- 2001-06-14 JP JP2002510089A patent/JP2004503502A/ja active Pending
- 2001-06-14 AU AU2001268407A patent/AU2001268407A1/en not_active Abandoned
- 2001-06-14 AP APAP/P/2002/002671A patent/AP2002002671A0/en unknown
- 2001-06-14 IL IL15342101A patent/IL153421A0/xx unknown
- 2001-06-14 KR KR1020027017045A patent/KR20030008220A/ko not_active Application Discontinuation
- 2001-06-14 CN CN01813500A patent/CN1444481A/zh active Pending
- 2001-06-14 BR BR0111693-2A patent/BR0111693A/pt not_active IP Right Cessation
- 2001-06-14 EA EA200300018A patent/EA200300018A1/ru unknown
- 2001-06-14 MX MXPA02012442A patent/MXPA02012442A/es unknown
- 2001-06-14 CZ CZ20024086A patent/CZ20024086A3/cs unknown
- 2001-06-14 WO PCT/US2001/019062 patent/WO2001095911A1/en active IP Right Grant
- 2001-06-14 SK SK1759-2002A patent/SK17592002A3/sk not_active Application Discontinuation
- 2001-06-14 CA CA002412353A patent/CA2412353A1/en not_active Abandoned
- 2001-06-14 OA OA1200200377A patent/OA12288A/en unknown
- 2001-06-14 NZ NZ522965A patent/NZ522965A/en unknown
- 2001-06-14 PL PL36050801A patent/PL360508A1/xx not_active Application Discontinuation
- 2001-06-14 AR ARP010102840A patent/AR032622A1/es not_active Application Discontinuation
- 2001-06-14 EP EP01946344A patent/EP1307204A4/en not_active Withdrawn
-
2002
- 2002-11-28 BG BG107327A patent/BG107327A/bg unknown
- 2002-12-02 NO NO20025786A patent/NO20025786L/no not_active Application Discontinuation
- 2002-12-03 ZA ZA200209808A patent/ZA200209808B/en unknown
- 2002-12-12 EC EC2002004388A patent/ECSP024388A/es unknown
- 2002-12-13 MA MA26952A patent/MA25758A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
EP1307204A1 (en) | 2003-05-07 |
JP2004503502A (ja) | 2004-02-05 |
CA2412353A1 (en) | 2001-12-20 |
AP2002002671A0 (en) | 2002-12-31 |
SK17592002A3 (sk) | 2003-05-02 |
BR0111693A (pt) | 2004-04-06 |
PL360508A1 (en) | 2004-09-06 |
MA25758A1 (fr) | 2003-04-01 |
NO20025786L (no) | 2003-02-12 |
NZ522965A (en) | 2004-06-25 |
CN1444481A (zh) | 2003-09-24 |
AR032622A1 (es) | 2003-11-19 |
MXPA02012442A (es) | 2003-04-25 |
HUP0301231A2 (hu) | 2003-08-28 |
WO2001095911A1 (en) | 2001-12-20 |
BG107327A (bg) | 2003-07-31 |
ECSP024388A (es) | 2003-02-06 |
EP1307204A4 (en) | 2004-06-02 |
AU2001268407A1 (en) | 2001-12-24 |
EA200300018A1 (ru) | 2003-06-26 |
NO20025786D0 (no) | 2002-12-02 |
CZ20024086A3 (cs) | 2003-05-14 |
OA12288A (en) | 2003-12-12 |
ZA200209808B (en) | 2004-07-09 |
KR20030008220A (ko) | 2003-01-24 |
IL153421A0 (en) | 2003-07-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20011233A1 (es) | Compuestos alquil aminoazepan-3-ona como inhibidores de proteasas | |
PE20001340A1 (es) | 4-amino-azepan-3-ona como inhibidores de proteasas | |
PE20011374A1 (es) | 4-amino-azepan-3-ona como inhibidores de proteasas | |
PE20010984A1 (es) | Derivados de nitrilo como inhibidores de catepsina k | |
PE110899A1 (es) | Derivados de acidos ariloxiarilsulfonilamino hidroxamicos | |
PE71599A1 (es) | Inhibidores de proteasas | |
PE20081583A1 (es) | Agentes antibacterianos derivados de compuestos carbonilamino | |
AU4688301A (en) | Stabilized pharmaceutical compositions containing calcium channel blockers | |
YU34896A (sh) | Supstituisani n-(indol-2-karbonil)-glicinamidi, njihovi intermedijeri i farmaceutske kompozicije | |
PE128799A1 (es) | Quinolinas antimicrobianas y sus composiciones | |
PE20031012A1 (es) | Compuesto inhibidor de la hepatitis c | |
PE20020786A1 (es) | Derivados de azaindol antiviral | |
PE20021014A1 (es) | Derivados de glutaramida sustituida con n-fenpropilciclopentilo como inhibidores de nep para fsad | |
DE69615058D1 (de) | Metalloproteinase inhibitoren | |
UY26820A1 (es) | Derivados de ciclopentil-glutaramida como inhibidores de endopeptidasa neutra | |
PE20050012A1 (es) | Compuestos de benzopirano como inhibidores de la ciclooxigenasa-2 | |
PE20090548A1 (es) | Compuestos aza-biciclohexano como inhibidores de trombina | |
ES2062486T3 (es) | 3-fenilbenzofuran-2-onas. | |
AR008621A1 (es) | Un compuesto derivado de amina succinica, un procedimiento para llevar a cabo su preparacion y una composicion farmaceutica que comprende dichocompuesto | |
PE64398A1 (es) | Derivados de azetidinona | |
PE20050312A1 (es) | Compuestos de peptidilo como inhibidores de catepsina s | |
PE20050160A1 (es) | 3-aminopirrolidinas como inhibidores de la captacion de monoaminas | |
PE20001486A1 (es) | Compuestos etereos anular de 7 a 14 miembros como inhibidores de proteasas | |
PE20001241A1 (es) | Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores | |
HUT39966A (en) | Insecticides containing as active substance acetilized sacharin-derivatives and process for production of this active substance |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |