PE18898A1 - Metodo para medicamentar el sistema de control inflamatorio y reacciones inflamatorias adversas y para fabricar compuestos para el tratamiento de la patologia de reacciones inflamatorias adversas - Google Patents
Metodo para medicamentar el sistema de control inflamatorio y reacciones inflamatorias adversas y para fabricar compuestos para el tratamiento de la patologia de reacciones inflamatorias adversasInfo
- Publication number
- PE18898A1 PE18898A1 PE1996000832A PE00083296A PE18898A1 PE 18898 A1 PE18898 A1 PE 18898A1 PE 1996000832 A PE1996000832 A PE 1996000832A PE 00083296 A PE00083296 A PE 00083296A PE 18898 A1 PE18898 A1 PE 18898A1
- Authority
- PE
- Peru
- Prior art keywords
- glucopyranosilamine
- glucose
- beta
- adverse
- inflammatory reactions
- Prior art date
Links
- 238000006243 chemical reaction Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000002757 inflammatory effect Effects 0.000 title 3
- 230000002411 adverse Effects 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000007170 pathology Effects 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-HQMMCQRPSA-N Ethanol-14C Chemical group C[14CH2]O LFQSCWFLJHTTHZ-HQMMCQRPSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229960001031 glucose Drugs 0.000 abstract 2
- 239000008103 glucose Substances 0.000 abstract 2
- -1 AMMONIUM IONS Chemical class 0.000 abstract 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 abstract 1
- 235000012538 ammonium bicarbonate Nutrition 0.000 abstract 1
- LFVGISIMTYGQHF-UHFFFAOYSA-N ammonium dihydrogen phosphate Chemical compound [NH4+].OP(O)([O-])=O LFVGISIMTYGQHF-UHFFFAOYSA-N 0.000 abstract 1
- 235000011114 ammonium hydroxide Nutrition 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003245 coal Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002702 enteric coating Substances 0.000 abstract 1
- 238000009505 enteric coating Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A COMPOSICIONES ANTIINFLAMATORIAS QUE COMPRENDEN: (I) DI-BETA-D-GLUCOPIRANOSILAMINA MEZCLADA CON UN VEHICULO; (II) UN RECUBRIMIENTO ENTERICO DE: a) GLUCOSA, b) NH4HCO3, c) UN AGENTE TERAPEUTICO COMPATIBLE, TAL COMO: ASPIRINA; (III) UNA MEZCLA ACUOSA DE: a) DI-BETA-D-GLUCOPIRANOSILAMINA, b) GLUCOSA, c) UN VEHICULO FARMACEUTICAMENTE ACEPTABLE, d) UNA FUENTE DE IONES AMONIO Y e) UN COMPUESTO ANTIACIDO. TAMBIEN SE REFIERE AL PROCEDIMIENTO DE PREPARACION DE LA DI-BETA-D-GLUCOPIRANOSILAMINA, QUE COMPRENDE: A) HACER REACCIONAR D(+)GLUCOSA, CON UNA BASE TAL COMO: NH4OH o NH4H2PO4/NaOH, YA SEA EN METANOL O ETANOL, PARA FORMAR GLUCOSILAMINA, B) EVAPORAR EL METANOL O ETANOL, C) AGREGAR CON AGITACION, UNA PASTA ACUOSA DE CARBON A LA MEZCLA, PARA ABSORBER LA DIGLUCOSILAMINA SOBRE EL CARBON, D) SEPARAR EL CARBON DEL AGUA, Y E) RECUPERAR LA DIGLUCOSILAMINA, OBTENIENDOSE UNA GLUCOPIRANOSILAMINA DE PUREZA MAS ALTA. USADOS EN EL TRATAMIENTO DE TRANSTORNOS DEL SISTEMA INMUNONEUROENDOCRINO INTEGRADO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/470,501 US5631245A (en) | 1995-06-06 | 1995-06-06 | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE18898A1 true PE18898A1 (es) | 1998-04-13 |
Family
ID=23867867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1996000832A PE18898A1 (es) | 1995-06-06 | 1996-11-20 | Metodo para medicamentar el sistema de control inflamatorio y reacciones inflamatorias adversas y para fabricar compuestos para el tratamiento de la patologia de reacciones inflamatorias adversas |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5631245A (es) |
| EP (1) | EP0831847B1 (es) |
| JP (1) | JPH11506766A (es) |
| CN (1) | CN1190891A (es) |
| AT (1) | ATE290386T1 (es) |
| AU (1) | AU721709B2 (es) |
| BR (1) | BR9608435A (es) |
| CA (1) | CA2222915A1 (es) |
| DE (1) | DE69634434D1 (es) |
| HU (1) | HUP9802541A2 (es) |
| IL (1) | IL122401A0 (es) |
| PE (1) | PE18898A1 (es) |
| WO (1) | WO1996039153A2 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5631245A (en) * | 1995-06-06 | 1997-05-20 | Biodynamics Pharmaceuticals, Inc. | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
| US6759434B2 (en) | 1999-09-22 | 2004-07-06 | B. Ron Johnson | Anti-infective compositions, methods and systems for treating disordered tissue |
| US8173709B2 (en) * | 1999-09-22 | 2012-05-08 | Quadex Pharmaceuticals, Llc | Anti-infective methods for treating pathogen-induced disordered tissues |
| US6211243B1 (en) | 1999-09-22 | 2001-04-03 | B. Ron Johnson | Methods for treating cold sores with anti-infective compositions |
| US20100129332A1 (en) * | 2000-07-31 | 2010-05-27 | Tamar Tennenbaum | Methods and pharmaceutical compositions for healing wounds |
| US20030148924A1 (en) * | 2002-07-09 | 2003-08-07 | Tamar Tennenbaum | Methods and pharmaceutical compositions of healing wounds |
| US20060258562A1 (en) * | 2000-07-31 | 2006-11-16 | Healor Ltd. | Methods and pharmaceutical compositions for healing wounds |
| US20040037828A1 (en) * | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| CA2359812C (en) | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
| DK1651161T3 (da) * | 2003-08-07 | 2012-01-30 | Healor Ltd | Farmaceutiske præparater og fremgangsmåder til at fremme sårheling |
| EP1660089A1 (en) * | 2003-08-22 | 2006-05-31 | Schering Aktiengesellschaft | Chemokine inhibiting piperazine derivatives and their use to treat myocarditis |
| WO2007026356A2 (en) * | 2005-08-29 | 2007-03-08 | Healor Ltd. | Methods and compositions for prevention and treatment of diabetic and aged skin |
| TR201807756T4 (tr) * | 2006-09-26 | 2018-06-21 | Infectious Disease Res Inst | Sentetik adjuvan içeren aşı bileşimi. |
| GB0622688D0 (en) * | 2006-11-14 | 2006-12-27 | Diosamine Dev Corp | Novel compounds |
| GB2450088A (en) * | 2007-06-11 | 2008-12-17 | Diosamine Dev Corp | Optionally modified monosaccharides with imine/iminium or glycosidic amine/ammonium group for use in modifying the level of cytokines & in therapy |
| US20100310542A1 (en) * | 2007-07-30 | 2010-12-09 | Healor Ltd. | Pharmaceutical Compositions for treating wouds and related methods |
| KR101098581B1 (ko) | 2009-01-09 | 2011-12-26 | 서울대학교산학협력단 | Ａｂｈ 항원을 이용한 염증질환 개선용 조성물 |
| GB201000196D0 (en) * | 2010-01-07 | 2010-02-24 | Galvez Julian M | Novel combination |
| AU2011204425A1 (en) | 2010-01-11 | 2012-08-02 | Healor Ltd. | Method for treatment of inflammatory disease and disorder |
| US8846725B2 (en) | 2011-01-24 | 2014-09-30 | Quadex Pharmaceuticals, Llc | Highly penetrating compositions and methods for treating pathogen-induced disordered tissues |
| US10953025B2 (en) * | 2011-07-14 | 2021-03-23 | Able Cerebral, Llc | Composition, device and method for delayed and sustained release of brain energy molecules |
| CN103945832B (zh) * | 2011-07-14 | 2017-03-29 | 能脑有限责任公司 | 用于脑能量分子延迟释放和持续释放的组合物，装置及方法 |
| US9463180B2 (en) | 2013-03-14 | 2016-10-11 | Quadex Pharmaceuticals, Llc | Treatment of molluscum contagiosum |
| US9125911B2 (en) | 2013-03-14 | 2015-09-08 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered tissues |
| US9549930B2 (en) | 2013-03-14 | 2017-01-24 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered and/or prodromal stage tissue |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE446299B (sv) * | 1978-04-11 | 1986-09-01 | Kureha Chemical Ind Co Ltd | Medicinsk komposition innehallande ett derivat av para-aminobensoesyra som aktiv bestandsdel |
| JPS56142211A (en) * | 1980-04-09 | 1981-11-06 | Riken Vitamin Co Ltd | Production of enteric preparation |
| DE3346623A1 (de) * | 1983-12-14 | 1985-07-04 | Bayer Ag, 5090 Leverkusen | N-glycosylierte harnstoffe, carbamate und thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung |
| DE3347522A1 (de) * | 1983-12-30 | 1985-07-11 | Troponwerke GmbH & Co KG, 5000 Köln | N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises |
| US4647453A (en) * | 1984-10-18 | 1987-03-03 | Peritain, Ltd. | Treatment for tissue degenerative inflammatory disease |
| US4772591A (en) * | 1985-09-25 | 1988-09-20 | Peritain, Ltd. | Method for accelerated wound healing |
| DE3602670A1 (de) * | 1986-01-29 | 1987-07-30 | Speck Ulrich | Verwendung von n-acetylglucosamin zur therapie degenerativer gelenkprozesse und verwandter erkrankungen |
| US4695590A (en) * | 1986-05-05 | 1987-09-22 | California Health Technologies | Method for retarding aging |
| US5219843A (en) * | 1987-09-23 | 1993-06-15 | Sandoz Ltd. | Saccharide derivatives |
| US5177062A (en) * | 1988-08-09 | 1993-01-05 | Mect Corporation | Method for treating immune complex diseases with n-acetylneuraminic acid |
| US5248668A (en) * | 1991-05-16 | 1993-09-28 | Wintek Consulting Ltd. | Use of purpurogallin and glycosides thereof in treating ischemia in mammals |
| ATE156707T1 (de) * | 1991-06-21 | 1997-08-15 | Ilsan Ilac Ve Hammaddeleri San | Neues galenisches verfahren für omeprazol enthaltende pellets |
| US5160742A (en) * | 1991-12-31 | 1992-11-03 | Abbott Laboratories | System for delivering an active substance for sustained release |
| US5362480A (en) * | 1991-12-31 | 1994-11-08 | Lever Brothers Company, Division Of Conopco, Inc. | Oral hygiene compositions containing amino sugars as antiplaque agents |
| US5631245A (en) * | 1995-06-06 | 1997-05-20 | Biodynamics Pharmaceuticals, Inc. | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
| US5872111A (en) * | 1997-05-19 | 1999-02-16 | Lever Brothers Company, Division Of Conopco, Inc. | Compositions comprising glycosylamide surfactants |
-
1995
- 1995-06-06 US US08/470,501 patent/US5631245A/en not_active Expired - Lifetime
-
1996
- 1996-06-06 BR BR9608435-9A patent/BR9608435A/pt not_active Application Discontinuation
- 1996-06-06 HU HU9802541A patent/HUP9802541A2/hu unknown
- 1996-06-06 AT AT96917988T patent/ATE290386T1/de not_active IP Right Cessation
- 1996-06-06 IL IL12240196A patent/IL122401A0/xx unknown
- 1996-06-06 EP EP96917988A patent/EP0831847B1/en not_active Expired - Lifetime
- 1996-06-06 CA CA002222915A patent/CA2222915A1/en not_active Abandoned
- 1996-06-06 WO PCT/US1996/008599 patent/WO1996039153A2/en active IP Right Grant
- 1996-06-06 JP JP9501138A patent/JPH11506766A/ja not_active Ceased
- 1996-06-06 DE DE69634434T patent/DE69634434D1/de not_active Expired - Lifetime
- 1996-06-06 CN CN96195548A patent/CN1190891A/zh active Pending
- 1996-06-06 AU AU60356/96A patent/AU721709B2/en not_active Ceased
- 1996-11-20 PE PE1996000832A patent/PE18898A1/es not_active Application Discontinuation
-
1997
- 1997-12-04 US US08/984,947 patent/US6770635B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9802541A2 (hu) | 1999-02-01 |
| AU6035696A (en) | 1996-12-24 |
| CN1190891A (zh) | 1998-08-19 |
| CA2222915A1 (en) | 1996-12-12 |
| BR9608435A (pt) | 2000-05-09 |
| IL122401A0 (en) | 1998-06-15 |
| US5631245A (en) | 1997-05-20 |
| EP0831847B1 (en) | 2005-03-09 |
| AU721709B2 (en) | 2000-07-13 |
| ATE290386T1 (de) | 2005-03-15 |
| EP0831847A2 (en) | 1998-04-01 |
| DE69634434D1 (de) | 2005-04-14 |
| MX9709751A (es) | 1998-07-31 |
| JPH11506766A (ja) | 1999-06-15 |
| US6770635B1 (en) | 2004-08-03 |
| WO1996039153A2 (en) | 1996-12-12 |
| WO1996039153A3 (en) | 1997-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |