ATE290386T1 - Verfahren zur herstellung von di-beta-d- glucopyranosylamin-verbindungen zur regulierung von entzündungsprozessen - Google Patents
Verfahren zur herstellung von di-beta-d- glucopyranosylamin-verbindungen zur regulierung von entzündungsprozessenInfo
- Publication number
- ATE290386T1 ATE290386T1 AT96917988T AT96917988T ATE290386T1 AT E290386 T1 ATE290386 T1 AT E290386T1 AT 96917988 T AT96917988 T AT 96917988T AT 96917988 T AT96917988 T AT 96917988T AT E290386 T1 ATE290386 T1 AT E290386T1
- Authority
- AT
- Austria
- Prior art keywords
- diglucosylamine
- glucose
- composition
- beta
- organism
- Prior art date
Links
- 230000004054 inflammatory process Effects 0.000 title abstract 6
- LTZXPZQIBOHOPK-LIZSDCNHSA-N (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]amino]oxane-3,4,5-triol Chemical class O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1N[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 LTZXPZQIBOHOPK-LIZSDCNHSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 abstract 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 4
- 239000008103 glucose Substances 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 230000002411 adverse Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 230000002032 cellular defenses Effects 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000007248 cellular mechanism Effects 0.000 abstract 1
- 239000003610 charcoal Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/470,501 US5631245A (en) | 1995-06-06 | 1995-06-06 | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
| PCT/US1996/008599 WO1996039153A2 (en) | 1995-06-06 | 1996-06-06 | Use of di-beta-d-glucopyranosylamine compounds for controlling inflammatory reactions, and method of synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290386T1 true ATE290386T1 (de) | 2005-03-15 |
Family
ID=23867867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96917988T ATE290386T1 (de) | 1995-06-06 | 1996-06-06 | Verfahren zur herstellung von di-beta-d- glucopyranosylamin-verbindungen zur regulierung von entzündungsprozessen |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5631245A (de) |
| EP (1) | EP0831847B1 (de) |
| JP (1) | JPH11506766A (de) |
| CN (1) | CN1190891A (de) |
| AT (1) | ATE290386T1 (de) |
| AU (1) | AU721709B2 (de) |
| BR (1) | BR9608435A (de) |
| CA (1) | CA2222915A1 (de) |
| DE (1) | DE69634434D1 (de) |
| HU (1) | HUP9802541A2 (de) |
| IL (1) | IL122401A0 (de) |
| PE (1) | PE18898A1 (de) |
| WO (1) | WO1996039153A2 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5631245A (en) * | 1995-06-06 | 1997-05-20 | Biodynamics Pharmaceuticals, Inc. | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
| US8173709B2 (en) * | 1999-09-22 | 2012-05-08 | Quadex Pharmaceuticals, Llc | Anti-infective methods for treating pathogen-induced disordered tissues |
| US6759434B2 (en) | 1999-09-22 | 2004-07-06 | B. Ron Johnson | Anti-infective compositions, methods and systems for treating disordered tissue |
| US6211243B1 (en) | 1999-09-22 | 2001-04-03 | B. Ron Johnson | Methods for treating cold sores with anti-infective compositions |
| US20040037828A1 (en) * | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| US20060258562A1 (en) * | 2000-07-31 | 2006-11-16 | Healor Ltd. | Methods and pharmaceutical compositions for healing wounds |
| US20100129332A1 (en) * | 2000-07-31 | 2010-05-27 | Tamar Tennenbaum | Methods and pharmaceutical compositions for healing wounds |
| US20030148924A1 (en) * | 2002-07-09 | 2003-08-07 | Tamar Tennenbaum | Methods and pharmaceutical compositions of healing wounds |
| CA2359812C (en) | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
| WO2005013885A2 (en) | 2003-08-07 | 2005-02-17 | Healor Ltd. | Pharmaceutical compositions and methods for accelerating wound healing |
| RU2006108865A (ru) * | 2003-08-22 | 2007-09-27 | Шеринг Акциенгезельшафт (De) | Производные пиперазина, которые ингибируют хемокины, и их применение для лечения миокардита |
| EP2452687A3 (de) * | 2005-08-29 | 2012-09-05 | HealOr Ltd. | Verfahren und Zusammensetzungen zur Vorbeugung und Behandlung von diabetischer und alternder Haut |
| HUE036180T2 (hu) * | 2006-09-26 | 2018-06-28 | Infectious Disease Res Inst | Szintetikus adjuvánst tartalmazó vakcina készítmény |
| GB0622688D0 (en) | 2006-11-14 | 2006-12-27 | Diosamine Dev Corp | Novel compounds |
| GB2450088A (en) * | 2007-06-11 | 2008-12-17 | Diosamine Dev Corp | Optionally modified monosaccharides with imine/iminium or glycosidic amine/ammonium group for use in modifying the level of cytokines & in therapy |
| CN101835486B (zh) * | 2007-07-30 | 2012-12-12 | 希尔洛有限公司 | 用于治疗创伤的药物组合物以及相关方法 |
| KR101098581B1 (ko) * | 2009-01-09 | 2011-12-26 | 서울대학교산학협력단 | Ａｂｈ 항원을 이용한 염증질환 개선용 조성물 |
| GB201000196D0 (en) * | 2010-01-07 | 2010-02-24 | Galvez Julian M | Novel combination |
| JP2013516500A (ja) | 2010-01-11 | 2013-05-13 | ヒールオア・リミテッド | 炎症性疾患および障害を治療するための方法 |
| US8846725B2 (en) | 2011-01-24 | 2014-09-30 | Quadex Pharmaceuticals, Llc | Highly penetrating compositions and methods for treating pathogen-induced disordered tissues |
| CA2878866C (en) * | 2011-07-14 | 2021-02-23 | Able Cerebral, Llc | A composition, device and method for delayed and sustained release of brain energy molecules |
| US10953025B2 (en) * | 2011-07-14 | 2021-03-23 | Able Cerebral, Llc | Composition, device and method for delayed and sustained release of brain energy molecules |
| US9549930B2 (en) | 2013-03-14 | 2017-01-24 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered and/or prodromal stage tissue |
| US9463180B2 (en) | 2013-03-14 | 2016-10-11 | Quadex Pharmaceuticals, Llc | Treatment of molluscum contagiosum |
| US9125911B2 (en) | 2013-03-14 | 2015-09-08 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered tissues |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE446299B (sv) * | 1978-04-11 | 1986-09-01 | Kureha Chemical Ind Co Ltd | Medicinsk komposition innehallande ett derivat av para-aminobensoesyra som aktiv bestandsdel |
| JPS56142211A (en) * | 1980-04-09 | 1981-11-06 | Riken Vitamin Co Ltd | Production of enteric preparation |
| DE3346623A1 (de) * | 1983-12-14 | 1985-07-04 | Bayer Ag, 5090 Leverkusen | N-glycosylierte harnstoffe, carbamate und thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung |
| DE3347522A1 (de) * | 1983-12-30 | 1985-07-11 | Troponwerke GmbH & Co KG, 5000 Köln | N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises |
| US4647453A (en) * | 1984-10-18 | 1987-03-03 | Peritain, Ltd. | Treatment for tissue degenerative inflammatory disease |
| US4772591A (en) * | 1985-09-25 | 1988-09-20 | Peritain, Ltd. | Method for accelerated wound healing |
| DE3602670A1 (de) * | 1986-01-29 | 1987-07-30 | Speck Ulrich | Verwendung von n-acetylglucosamin zur therapie degenerativer gelenkprozesse und verwandter erkrankungen |
| US4695590A (en) * | 1986-05-05 | 1987-09-22 | California Health Technologies | Method for retarding aging |
| US5219843A (en) * | 1987-09-23 | 1993-06-15 | Sandoz Ltd. | Saccharide derivatives |
| US5177062A (en) * | 1988-08-09 | 1993-01-05 | Mect Corporation | Method for treating immune complex diseases with n-acetylneuraminic acid |
| US5248668A (en) * | 1991-05-16 | 1993-09-28 | Wintek Consulting Ltd. | Use of purpurogallin and glycosides thereof in treating ischemia in mammals |
| ATE156707T1 (de) * | 1991-06-21 | 1997-08-15 | Ilsan Ilac Ve Hammaddeleri San | Neues galenisches verfahren für omeprazol enthaltende pellets |
| US5160742A (en) * | 1991-12-31 | 1992-11-03 | Abbott Laboratories | System for delivering an active substance for sustained release |
| US5362480A (en) * | 1991-12-31 | 1994-11-08 | Lever Brothers Company, Division Of Conopco, Inc. | Oral hygiene compositions containing amino sugars as antiplaque agents |
| US5631245A (en) * | 1995-06-06 | 1997-05-20 | Biodynamics Pharmaceuticals, Inc. | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
| US5872111A (en) * | 1997-05-19 | 1999-02-16 | Lever Brothers Company, Division Of Conopco, Inc. | Compositions comprising glycosylamide surfactants |
-
1995
- 1995-06-06 US US08/470,501 patent/US5631245A/en not_active Expired - Lifetime
-
1996
- 1996-06-06 AU AU60356/96A patent/AU721709B2/en not_active Ceased
- 1996-06-06 WO PCT/US1996/008599 patent/WO1996039153A2/en not_active Ceased
- 1996-06-06 DE DE69634434T patent/DE69634434D1/de not_active Expired - Lifetime
- 1996-06-06 CN CN96195548A patent/CN1190891A/zh active Pending
- 1996-06-06 EP EP96917988A patent/EP0831847B1/de not_active Expired - Lifetime
- 1996-06-06 BR BR9608435-9A patent/BR9608435A/pt not_active Application Discontinuation
- 1996-06-06 JP JP9501138A patent/JPH11506766A/ja not_active Ceased
- 1996-06-06 HU HU9802541A patent/HUP9802541A2/hu unknown
- 1996-06-06 AT AT96917988T patent/ATE290386T1/de not_active IP Right Cessation
- 1996-06-06 IL IL12240196A patent/IL122401A0/xx unknown
- 1996-06-06 CA CA002222915A patent/CA2222915A1/en not_active Abandoned
- 1996-11-20 PE PE1996000832A patent/PE18898A1/es not_active Application Discontinuation
-
1997
- 1997-12-04 US US08/984,947 patent/US6770635B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69634434D1 (de) | 2005-04-14 |
| WO1996039153A2 (en) | 1996-12-12 |
| AU721709B2 (en) | 2000-07-13 |
| CA2222915A1 (en) | 1996-12-12 |
| US6770635B1 (en) | 2004-08-03 |
| JPH11506766A (ja) | 1999-06-15 |
| AU6035696A (en) | 1996-12-24 |
| BR9608435A (pt) | 2000-05-09 |
| PE18898A1 (es) | 1998-04-13 |
| EP0831847A2 (de) | 1998-04-01 |
| IL122401A0 (en) | 1998-06-15 |
| WO1996039153A3 (en) | 1997-03-27 |
| MX9709751A (es) | 1998-07-31 |
| HUP9802541A2 (hu) | 1999-02-01 |
| EP0831847B1 (de) | 2005-03-09 |
| CN1190891A (zh) | 1998-08-19 |
| US5631245A (en) | 1997-05-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE290386T1 (de) | Verfahren zur herstellung von di-beta-d- glucopyranosylamin-verbindungen zur regulierung von entzündungsprozessen | |
| EG20001A (en) | Process for preparing of novel hydrox-amic acid and N-hydroxyurea derivatives and their use | |
| HUP9600448A2 (hu) | Naftilvegyületek, e vegyületeket tartalmazó gyógyszerkészítmények, eljárás előállításukra, intermedierjeik és alkalmazásuk | |
| CA2258548A1 (en) | Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases | |
| CA2260777A1 (en) | Pentafluorobenzenesulfonamides and analogs | |
| GEP20053421B (en) | Substituted Pyrazoles As P38 Kinase Inhibitors, Method for Their Production and Pharmaceutical Compositions Containing Them | |
| RU95110938A (ru) | Производные 1-(2-оксоацетил)пиперидин-2-карбоновых кислот, фармацевтическая композиция, способ лечения, способ получения | |
| BG101727A (bg) | 1,2,4-тризаместени имидазоли, полезни като цитокини | |
| DE69531502D1 (de) | Monoamid, diamid, thiol enthaltende metall-chelatierende verbindungen | |
| BE853086A (fr) | Compositions pharmaceutiques contenant comme ingredients actifs des derives de triazolo-pyrimidines utiles pour le traitement de psoriasis | |
| DE3172298D1 (en) | Pharmaceutical compositions | |
| TNSN90021A1 (fr) | Procede de preparation de tetrahydroimidazo (1,4) benzodiazepin -2- thiones antivirales | |
| RU94038256A (ru) | Производные пиразолопиримидина, способ их получения, фармацевтические композиции на их основе | |
| FI854926A0 (fi) | Foerfarande foer framstaellning av farmakologiskt aktiva pyrrolobensimidazoler. | |
| IE43693L (en) | Androstane derivatives | |
| HU9303000D0 (en) | Aryl-morpholine-derivatives and pharmaceutical compositions containing it and process for production thereof | |
| CA2031897A1 (en) | Carbamoyl derivatives | |
| RU94031479A (ru) | Новое применение производных аминокислот, способ лечения, фармацевтическая композиция | |
| FI974444A0 (fi) | N-hydroksiureayhdisteitä anti-inflammatorisina aineina | |
| DE69103773D1 (de) | Derivate von hydroxaminsäure die lipoxygenase hemmen. | |
| FR2384791A1 (fr) | Nouveaux derives d'everninomicine, leur procede de preparation et compositions pharmaceutiques contenant lesdits derives | |
| AR004353A1 (es) | Metodo para medicamentar el sistema de control inflamatorio y reacciones inflamatorias adversas y para fabricar compuestos para el tratamiento de lapatologia de reacciones inflamatorias adversas. | |
| RU94035756A (ru) | Производные имидазола, являющиеся ингибиторами питокинов, способы их получения, фармацевтическая композиция |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |