MX9709751A - Metodo para medicamentar el sistema de control inflamatorio y reacciones inflamatorias adversas y para fabricar compuestos para el tratamiento de la patologia de reacciones inflamatorias adversas. - Google Patents

Metodo para medicamentar el sistema de control inflamatorio y reacciones inflamatorias adversas y para fabricar compuestos para el tratamiento de la patologia de reacciones inflamatorias adversas.

Info

Publication number
MX9709751A
MX9709751A MX9709751A MX9709751A MX9709751A MX 9709751 A MX9709751 A MX 9709751A MX 9709751 A MX9709751 A MX 9709751A MX 9709751 A MX9709751 A MX 9709751A MX 9709751 A MX9709751 A MX 9709751A
Authority
MX
Mexico
Prior art keywords
diglucosylamine
glucose
composition
inflammatory reactions
glucopyranosylamine
Prior art date
Application number
MX9709751A
Other languages
English (en)
Other versions
MXPA97009751A (es
Inventor
Clairmont G Drube
Original Assignee
Biodynamics Pharmaceuticals In
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biodynamics Pharmaceuticals In filed Critical Biodynamics Pharmaceuticals In
Publication of MX9709751A publication Critical patent/MX9709751A/es
Publication of MXPA97009751A publication Critical patent/MXPA97009751A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Las reacciones inflamatorias adversas se pueden tratar mediante la administracion a un organismo de una composicion que tiene diglucosilamina como el ingrediente activo. El compuesto preferido es di-Beta-D-glucopiranosilamina. Se obtiene un método simple para fabricar diglucosilamina en una alta pureza mediante la reaccion de glucosa, una base que contiene nitrogeno, y ya sea metanol o etanol para formar la diglucosilamina, y luego se recupera la diglucosilamina de preferencia con el uso de carbon. La diglucosilamina preferida, di-Beta-D-glulcopiranosilamina, tiene una extraordinara actividad antiinflamatoria. Se puede formular con un vehículo farmacéuticamente aceptable para hacer composiciones farmacéuticas que son efectivas en el tratamiento de inflamaciones. Esta composicion farmacéutica también se puede utilizar para tratar reacciones inflamatorias adversas que son el resultado de las alteraciones de una red dinámica de los mecanismos celulares de los organismos. En adicion, la aplicacion de esta composicion también sirve para restablecer el equilibrio de la red de defensa celular en un organismo que tiene su red de defensa celular desequilibrada. En este caso de desequilibrio, la composicion sirve para tratar la patología de la inflamacion y activa el sistema de control de inglamcaciones in vivo. Estas reacciones inflamatorias adversas también se pueden tratar mediante la administracion al organismo de glucosa en la presencia de iones de NH3+ y a un pH de aproximadamente 7.0o mayor. La glucosa se puede aplicar de preferencia mediante la administracion iral de y una forma con recubrimiento entérico de glucosa, sola o en combinacion con otros medicamentos.
MXPA/A/1997/009751A 1995-06-06 1997-12-05 Metodo para medicamentar el sistema de control inflamatorio y reacciones inflamatorias adversas y para fabricar compuestos para el tratamiento de la patologia de reacciones inflamatorias adversas MXPA97009751A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/470,501 US5631245A (en) 1995-06-06 1995-06-06 Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions
US08470501 1995-06-06

Publications (2)

Publication Number Publication Date
MX9709751A true MX9709751A (es) 1998-07-31
MXPA97009751A MXPA97009751A (es) 1998-11-09

Family

ID=

Also Published As

Publication number Publication date
EP0831847B1 (en) 2005-03-09
AU721709B2 (en) 2000-07-13
EP0831847A2 (en) 1998-04-01
US6770635B1 (en) 2004-08-03
IL122401A0 (en) 1998-06-15
JPH11506766A (ja) 1999-06-15
ATE290386T1 (de) 2005-03-15
PE18898A1 (es) 1998-04-13
CA2222915A1 (en) 1996-12-12
DE69634434D1 (de) 2005-04-14
AU6035696A (en) 1996-12-24
CN1190891A (zh) 1998-08-19
BR9608435A (pt) 2000-05-09
HUP9802541A2 (hu) 1999-02-01
WO1996039153A2 (en) 1996-12-12
US5631245A (en) 1997-05-20
WO1996039153A3 (en) 1997-03-27

Similar Documents

Publication Publication Date Title
WO1996039153A3 (en) Use of di-beta-d-glucopyranosylamine compounds for controlling inflammatory reactions, and method of synthesis
MY107341A (en) Novel hydroxamic acid and n-hydroxyurea derivatives and their use
CA2258548A1 (en) Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases
TR199900674T2 (xx) Kinazolin t�revleri ve bunlar� i�eren farmas�tik bile�imler.
CA2260777A1 (en) Pentafluorobenzenesulfonamides and analogs
DE69531502D1 (de) Monoamid, diamid, thiol enthaltende metall-chelatierende verbindungen
GEP20053421B (en) Substituted Pyrazoles As P38 Kinase Inhibitors, Method for Their Production and Pharmaceutical Compositions Containing Them
CA2219115A1 (en) N-benzyl-3-indoleacetic acids as cyclooxygenase-2-inhibitors and antiinflammatory drugs
FR2435471A1 (fr) Derives de dihydropyridine, procedes d'obtention et compositions pharmaceutiques en contenant
RU94046411A (ru) Производные витамина д, способ их получения, фармацевтическая композиция на их основе и способ ее получения, способ лечения
GB2075341B (en) Pharmaceutical compositions
IL107287A (en) Heterocyclic derivatives process for their preparation and pharmaceutical compositions containing some of them
IE43693L (en) Androstane derivatives
RU94038256A (ru) Производные пиразолопиримидина, способ их получения, фармацевтические композиции на их основе
MX9403088A (es) Composiciones farmaceuticas que contienen deriva- dos de indol y metodos de uso.
EP0779889A4 (en) PYRAZOLO 3,4-g] QUINOXALINE COMPOUNDS INHIBITING FCDP RECEPTOR PROTEIN TYROSINE KINASE
AU2351095A (en) Benzimidazole derivatives having dopaminergic activity
HU9303000D0 (en) Aryl-morpholine-derivatives and pharmaceutical compositions containing it and process for production thereof
ZA979647B (en) Heterocyclic compounds, compositions and uses.
AU534470B2 (en) Paromomycin derivatives
NZ287551A (en) N-hydroxyureas that inhibit the 5-lipoxygenase enzyme as anti-inflammatory agents
GB1476698A (en) Quinazolinone derivatives and therapeutic compositions containing them
ZA979645B (en) Heterocyclic compounds, compositions and uses.
ZA979650B (en) Heterocyclic compounds, compositions and uses.
FR2384791A1 (fr) Nouveaux derives d'everninomicine, leur procede de preparation et compositions pharmaceutiques contenant lesdits derives