PE100298A1 - Tratamiento de las respuestas alergicas de la vias respiratorias superiores - Google Patents

Tratamiento de las respuestas alergicas de la vias respiratorias superiores

Info

Publication number
PE100298A1
PE100298A1 PE1997000705A PE00070597A PE100298A1 PE 100298 A1 PE100298 A1 PE 100298A1 PE 1997000705 A PE1997000705 A PE 1997000705A PE 00070597 A PE00070597 A PE 00070597A PE 100298 A1 PE100298 A1 PE 100298A1
Authority
PE
Peru
Prior art keywords
histamine
components
antagonist
treatment
entrezos
Prior art date
Application number
PE1997000705A
Other languages
English (en)
Inventor
William Kreutner
John A Hey
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE100298A1 publication Critical patent/PE100298A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION QUE COMPRENDE: A) UNA CANTIDAD ANTIHISTAMINICA EFICAZ DE UN ANTAGONISTA RECEPTOR DE HISTAMINA H1 QUE SE SELECCIONA DEL GRUPO CONFORMADO POR: ASTEMIZOL, AZATADINA, AZELASTINA, ACRIVASTINA, LORATADINA, ENTRE OTROS, Y MEZCLAS DE LOS MISMOS; Y B) UNA CANTIDAD SUFICIENTE DE UN ANTAGONISTA RECEPTOR DE HISTAMINA H3, QUE SE SELECCIONA DEL GRUPO CONFORMADO POR: TIOPERAMIDA, IMPROMIDINA, BURIMAMIDA, IMPENTAMINA, ENTRE OTROS, Y MEZCLAS DE DOS O MAS DE LOS MISMOS, PARA PROVEER UN EFECTO DESCONGESTIVO NASAL; EN UN PORTADOR FARMACEUTICAMENTE ACEPTABLE; DONDE DICHOS COMPONENTES SE PUEDEN COMBINAR EN UNA FORMA DE DOSIFICACION SOLIDA O LIQUIDA. SE REFIERE TAMBIEN A UN METODO PARA ALIVIAR LOS SINTOMAS DE RINITIS EN UN MAMIFERO QUE COMPRENDE MANTENER SIMULTANEAMENTE EN EL SISTEMA CIRCULATORIO: A) UN ANTAGONISTA RECEPTOR DE HISTAMINA H1; Y B) UN ANTAGONISTA RECEPTOR DE HISTAMINA H3; DONDE DICHOS COMPONENTES PUEDEN ADMINISTRARSE EN FORMA DE DOSIFICACION CONJUNTA UNICA, O POR SEPARADO EN FORMAS DE DOSIFICACION IGUALES O DIFERENTES PARA MANTENER LOS NIVELES SISTEMICOS TERAPEUTICOS DE AMBOS COMPONENTES
PE1997000705A 1996-08-16 1997-08-13 Tratamiento de las respuestas alergicas de la vias respiratorias superiores PE100298A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68995196A 1996-08-16 1996-08-16

Publications (1)

Publication Number Publication Date
PE100298A1 true PE100298A1 (es) 1999-01-11

Family

ID=24770500

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1997000705A PE100298A1 (es) 1996-08-16 1997-08-13 Tratamiento de las respuestas alergicas de la vias respiratorias superiores

Country Status (25)

Country Link
EP (1) EP0920315B1 (es)
JP (2) JP3638289B2 (es)
KR (1) KR20000029975A (es)
CN (1) CN1152682C (es)
AR (1) AR008293A1 (es)
AT (1) ATE314071T1 (es)
AU (1) AU722040B2 (es)
BR (1) BR9711149A (es)
CA (1) CA2263163A1 (es)
CO (1) CO4910138A1 (es)
CZ (1) CZ43299A3 (es)
DE (1) DE69734984D1 (es)
HU (1) HUP9904362A3 (es)
ID (1) ID17871A (es)
IL (1) IL128573A0 (es)
MY (1) MY116130A (es)
NO (1) NO990706D0 (es)
NZ (1) NZ334063A (es)
PE (1) PE100298A1 (es)
PL (1) PL191073B1 (es)
SK (1) SK20099A3 (es)
TR (1) TR199900326T2 (es)
TW (2) TWI221768B (es)
WO (1) WO1998006394A1 (es)
ZA (1) ZA977263B (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ527201A (en) * 1997-03-26 2004-12-24 Sepracor Inc Stable norastemizole formulations comprising coated norastemizole particles
NZ501248A (en) * 1997-08-26 2001-06-29 Aventis Pharma Inc Pharmaceutical composition for combination of piperidinoalkanol-decongestant
US6034251A (en) * 1997-11-07 2000-03-07 Schering Corporation Phenyl-alkyl-imidazoles
US5990147A (en) * 1997-11-07 1999-11-23 Schering Corporation H3 receptor ligands of the phenyl-alkyl-imidazoles type
ES2188029T3 (es) * 1997-11-07 2003-06-16 Schering Corp Fenil-alquil-imidazoles como antagonistas del receptor h3.
CN1130349C (zh) * 1997-11-07 2003-12-10 先灵公司 苯基-烷基-咪唑类型的h3受体配体
HUP0102662A3 (en) * 1997-11-07 2003-01-28 Schering Corp Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom
US6384038B1 (en) * 1998-04-14 2002-05-07 Sepracor Inc. Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants
EP1117405A2 (en) * 1998-10-09 2001-07-25 Schering Corporation Composition and method for treating allergic diseases
US6100279A (en) * 1998-11-05 2000-08-08 Schering Corporation Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom
EP1214071A2 (en) * 1999-09-22 2002-06-19 Schering Corporation Treating allergic and inflammatory conditions using desloratadine
HUP0204048A3 (en) 2000-02-03 2004-07-28 Schering Corp Use of desloratadine for treating allergic and inflammatory conditions
PE20020507A1 (es) 2000-10-17 2002-06-25 Schering Corp Compuestos no-imidazoles como antagonistas del receptor histamina h3
GB2373186A (en) * 2001-02-23 2002-09-18 Astrazeneca Ab Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation
CN1298715C (zh) 2001-03-13 2007-02-07 先灵公司 作为组胺h3拮抗剂的非咪唑化合物
JP4563800B2 (ja) 2002-04-18 2010-10-13 シェーリング コーポレイション ヒスタミンh3アンタゴニストとしての1−(4−ピペリジニル)ベンズイミダゾロン
US7105505B2 (en) 2002-04-18 2006-09-12 Schering Corporation Benzimidazole derivatives useful as histamine H3 antagonists
DE60309598T2 (de) 2002-06-24 2007-09-13 Schering Corp. Als histamin-h3-antagonisten geeignete indolderivate
US20050090527A1 (en) * 2003-01-28 2005-04-28 Schering Corporation Combination of H1, H3 and H4 receptor antagonists for treatment of allergic and non-allergic pulmonary inflammation, congestion and allergic rhinitis
AU2006262441A1 (en) 2005-06-20 2007-01-04 Schering Corporation Piperidine derivatives useful as histamine H3 antagonists
EP2318388A2 (en) 2008-07-23 2011-05-11 Schering Corporation Tricyclic spirocycle derivatives and methods of use thereof
CA2739491A1 (en) 2008-10-16 2010-04-22 Schering Corporation Azine derivatives and methods of use thereof
WO2010071822A1 (en) 2008-12-19 2010-06-24 Schering Corporation Piperidine and piperazine derivatives and methods of use thereof
WO2010071819A1 (en) 2008-12-19 2010-06-24 Schering Corporation Bicyclic heterocyclic derivatives and methods of use thereof
US9254286B2 (en) 2009-03-17 2016-02-09 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
US8569273B2 (en) 2009-03-17 2013-10-29 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
CN107582551A (zh) * 2009-05-14 2018-01-16 总医院公司 治疗退化性及缺血性疾病的方法和组合物
EP2485735B1 (en) 2009-10-08 2015-07-29 Merck Sharp & Dohme Corp. Inhibitors of fatty acid binding protein (fabp)
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
RU2685277C1 (ru) * 2018-05-24 2019-04-17 Общество с ограниченной ответственностью "Фарминтерпрайсез Аллерджи" Применение бисамидного производного малоновой кислоты для лечения аллергических и других заболеваний человека и животных

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201683B (en) * 1987-08-04 1990-12-28 Biogal Gyogyszergyar Process for producing pharmaceutical compositions for promoting healing of wounds
US5019591A (en) * 1989-02-17 1991-05-28 Pennsylvania Research Corporation Method for treating retinopathy and other small vessel disorders associated with diabetes
GB9303210D0 (en) * 1993-02-17 1993-03-31 Univ Manitoba Cancer treatment

Also Published As

Publication number Publication date
NZ334063A (en) 2000-09-29
AU722040B2 (en) 2000-07-20
NO990706L (no) 1999-02-15
WO1998006394A1 (en) 1998-02-19
SK20099A3 (en) 2000-08-14
ATE314071T1 (de) 2006-01-15
HUP9904362A2 (hu) 2000-11-28
EP0920315A1 (en) 1999-06-09
DE69734984D1 (de) 2006-02-02
BR9711149A (pt) 1999-08-17
NO990706D0 (no) 1999-02-15
KR20000029975A (ko) 2000-05-25
TR199900326T2 (xx) 1999-05-21
CO4910138A1 (es) 2000-04-24
JP3638289B2 (ja) 2005-04-13
CA2263163A1 (en) 1998-02-19
ZA977263B (en) 1998-02-16
AR008293A1 (es) 1999-12-29
IL128573A0 (en) 2000-01-31
JP2003095979A (ja) 2003-04-03
PL331617A1 (en) 1999-08-02
TW200427450A (en) 2004-12-16
HUP9904362A3 (en) 2000-12-28
JP2000505094A (ja) 2000-04-25
CZ43299A3 (cs) 1999-07-14
CN1233179A (zh) 1999-10-27
TWI221768B (en) 2004-10-11
EP0920315B1 (en) 2005-12-28
CN1152682C (zh) 2004-06-09
PL191073B1 (pl) 2006-03-31
MY116130A (en) 2003-11-28
ID17871A (id) 1998-02-05
AU3973397A (en) 1998-03-06

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