PA8577801A1 - Polipeptido t1249 pegilado - Google Patents
Polipeptido t1249 pegiladoInfo
- Publication number
- PA8577801A1 PA8577801A1 PA20038577801A PA8577801A PA8577801A1 PA 8577801 A1 PA8577801 A1 PA 8577801A1 PA 20038577801 A PA20038577801 A PA 20038577801A PA 8577801 A PA8577801 A PA 8577801A PA 8577801 A1 PA8577801 A1 PA 8577801A1
- Authority
- PA
- Panama
- Prior art keywords
- polypeptide
- pegilated
- composites
- inhibition
- pharmaceutically acceptable
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
- C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
- C07K14/16—HIV-1 ; HIV-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- AIDS & HIV (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
SE PROPORCIONAN COMPUESTOS DEL POLIPEPTIDO T1249 PEGILADO. TAMBIEN SE PROPORCIONAN COMPOSICIONES FARMACEUTICAS QUE CONTIENEN COMPUESTOS DEL POLIPEPTIDO T1249 PEGILADO, Y PROCESOS DE FABRICACION. ADEMAS SE PROPORCIONA EL USO QUE COMPRENDE LA COMPOSICION FARMACEUTICA, EN UNA MEZCLA CON UN EXCIPIENTE FARMACEUTICAMENTE ACEPTABLE, UN COMPUESTO DE FORMULA I, PARA LA PREPARACION DE UN MEDICAMENTO PARA LA INHIBICION DE LA INFECCION POR VIH.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39819002P | 2002-07-24 | 2002-07-24 | |
US43921303P | 2003-01-10 | 2003-01-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8577801A1 true PA8577801A1 (es) | 2004-05-26 |
Family
ID=31498587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20038577801A PA8577801A1 (es) | 2002-07-24 | 2003-07-21 | Polipeptido t1249 pegilado |
Country Status (21)
Country | Link |
---|---|
US (1) | US7084261B2 (es) |
EP (1) | EP1546193A1 (es) |
JP (1) | JP4381302B2 (es) |
KR (1) | KR100630176B1 (es) |
CN (1) | CN100352837C (es) |
AR (1) | AR040650A1 (es) |
AU (1) | AU2003250079B2 (es) |
BR (1) | BR0312841A (es) |
CA (1) | CA2492954C (es) |
HR (1) | HRP20050025A2 (es) |
IL (1) | IL166037A0 (es) |
MX (1) | MXPA05000798A (es) |
NO (1) | NO20050067L (es) |
NZ (1) | NZ537493A (es) |
PA (1) | PA8577801A1 (es) |
PE (1) | PE20040679A1 (es) |
PL (1) | PL375308A1 (es) |
RU (1) | RU2294938C2 (es) |
TW (1) | TW200427697A (es) |
UY (1) | UY27900A1 (es) |
WO (1) | WO2004013165A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2004308952A1 (en) * | 2003-12-23 | 2005-07-14 | Centocor, Inc. | Anti-retroviral agents, compositions, methods and uses |
EP1720899A2 (en) * | 2004-02-23 | 2006-11-15 | Borean Pharma A/S | Multimerised hiv fusion inhibitors |
MXPA06010505A (es) * | 2004-03-15 | 2006-12-19 | Nektar Therapeutics Al Corp | Composiciones y conjugados, basados en polimeros, de inhibidores de ingreso de vih. |
CN100475270C (zh) * | 2006-01-20 | 2009-04-08 | 清华大学 | 一种治疗肿瘤的药物及其应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR850004274A (ko) * | 1983-12-13 | 1985-07-11 | 원본미기재 | 에리트로포이에틴의 제조방법 |
US5252714A (en) * | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
US5464933A (en) * | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
US5795569A (en) * | 1994-03-31 | 1998-08-18 | Amgen Inc. | Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation |
CH690143A5 (de) * | 1995-01-27 | 2000-05-15 | Rieter Automotive Int Ag | Lambda/4-Schallabsorber. |
US5672662A (en) * | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
US5830879A (en) * | 1995-10-02 | 1998-11-03 | St. Elizabeth's Medical Center Of Boston, Inc. | Treatment of vascular injury using vascular endothelial growth factor |
US5990237A (en) * | 1997-05-21 | 1999-11-23 | Shearwater Polymers, Inc. | Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines |
US6281331B1 (en) * | 1998-03-23 | 2001-08-28 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
US6258782B1 (en) * | 1998-05-20 | 2001-07-10 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
PE20010288A1 (es) * | 1999-07-02 | 2001-03-07 | Hoffmann La Roche | Derivados de eritropoyetina |
US6469136B1 (en) * | 1999-07-07 | 2002-10-22 | Trimeris, Inc. | Methods and composition for peptide synthesis |
-
2003
- 2003-07-16 EP EP03766191A patent/EP1546193A1/en not_active Withdrawn
- 2003-07-16 JP JP2004525220A patent/JP4381302B2/ja not_active Expired - Lifetime
- 2003-07-16 WO PCT/EP2003/007711 patent/WO2004013165A1/en active Application Filing
- 2003-07-16 IL IL16603703A patent/IL166037A0/xx unknown
- 2003-07-16 CA CA002492954A patent/CA2492954C/en not_active Expired - Fee Related
- 2003-07-16 CN CNB038176793A patent/CN100352837C/zh not_active Expired - Fee Related
- 2003-07-16 KR KR1020057001145A patent/KR100630176B1/ko not_active IP Right Cessation
- 2003-07-16 AU AU2003250079A patent/AU2003250079B2/en not_active Ceased
- 2003-07-16 PL PL03375308A patent/PL375308A1/xx not_active Application Discontinuation
- 2003-07-16 RU RU2005105578/04A patent/RU2294938C2/ru not_active IP Right Cessation
- 2003-07-16 MX MXPA05000798A patent/MXPA05000798A/es active IP Right Grant
- 2003-07-16 NZ NZ537493A patent/NZ537493A/en unknown
- 2003-07-16 BR BR0312841-5A patent/BR0312841A/pt not_active IP Right Cessation
- 2003-07-18 TW TW092119718A patent/TW200427697A/zh unknown
- 2003-07-21 PA PA20038577801A patent/PA8577801A1/es unknown
- 2003-07-21 PE PE2003000723A patent/PE20040679A1/es not_active Application Discontinuation
- 2003-07-22 US US10/625,103 patent/US7084261B2/en not_active Expired - Fee Related
- 2003-07-22 UY UY27900A patent/UY27900A1/es not_active Application Discontinuation
- 2003-07-22 AR AR20030102620A patent/AR040650A1/es unknown
-
2005
- 2005-01-06 NO NO20050067A patent/NO20050067L/no not_active Application Discontinuation
- 2005-01-11 HR HR20050025A patent/HRP20050025A2/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2006515272A (ja) | 2006-05-25 |
UY27900A1 (es) | 2003-12-31 |
NO20050067L (no) | 2005-04-22 |
AU2003250079B2 (en) | 2006-07-27 |
AU2003250079A1 (en) | 2004-02-23 |
HRP20050025A2 (en) | 2006-02-28 |
MXPA05000798A (es) | 2005-04-19 |
RU2005105578A (ru) | 2005-10-27 |
CA2492954A1 (en) | 2004-02-12 |
CN100352837C (zh) | 2007-12-05 |
KR100630176B1 (ko) | 2006-10-02 |
EP1546193A1 (en) | 2005-06-29 |
WO2004013165A1 (en) | 2004-02-12 |
BR0312841A (pt) | 2005-12-06 |
AR040650A1 (es) | 2005-04-13 |
TW200427697A (en) | 2004-12-16 |
PL375308A1 (en) | 2005-11-28 |
CA2492954C (en) | 2009-12-22 |
JP4381302B2 (ja) | 2009-12-09 |
IL166037A0 (en) | 2006-01-15 |
CN1671735A (zh) | 2005-09-21 |
PE20040679A1 (es) | 2004-10-06 |
US20040171542A1 (en) | 2004-09-02 |
KR20050027255A (ko) | 2005-03-18 |
RU2294938C2 (ru) | 2007-03-10 |
US7084261B2 (en) | 2006-08-01 |
NZ537493A (en) | 2007-05-31 |
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