OA12597A - Processes and intermediates for preparing benzyl substituted epoxides. - Google Patents
Processes and intermediates for preparing benzyl substituted epoxides. Download PDFInfo
- Publication number
- OA12597A OA12597A OA1200300276A OA1200300276A OA12597A OA 12597 A OA12597 A OA 12597A OA 1200300276 A OA1200300276 A OA 1200300276A OA 1200300276 A OA1200300276 A OA 1200300276A OA 12597 A OA12597 A OA 12597A
- Authority
- OA
- OAPI
- Prior art keywords
- alkyl
- optionally substituted
- halogen
- phenyl
- prot
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/24—Synthesis of the oxirane ring by splitting off HAL—Y from compounds containing the radical HAL—C—C—OY
- C07D301/26—Y being hydrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28577201P | 2001-04-23 | 2001-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA12597A true OA12597A (en) | 2006-06-08 |
Family
ID=23095626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA1200300276A OA12597A (en) | 2001-04-23 | 2002-04-23 | Processes and intermediates for preparing benzyl substituted epoxides. |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US6849750B2 (fr) |
| EP (1) | EP1381597B1 (fr) |
| JP (1) | JP2004529152A (fr) |
| KR (1) | KR20040047750A (fr) |
| CN (1) | CN1612871A (fr) |
| AP (1) | AP2003002897A0 (fr) |
| AR (1) | AR035960A1 (fr) |
| AT (1) | ATE401299T1 (fr) |
| BR (1) | BR0209163A (fr) |
| CA (1) | CA2445163A1 (fr) |
| CO (1) | CO5650163A2 (fr) |
| DE (1) | DE60227652D1 (fr) |
| EA (1) | EA007535B1 (fr) |
| ES (1) | ES2309170T3 (fr) |
| IL (2) | IL158585A0 (fr) |
| MX (1) | MXPA03009723A (fr) |
| NO (1) | NO20034738L (fr) |
| NZ (1) | NZ529169A (fr) |
| OA (1) | OA12597A (fr) |
| PE (1) | PE20021068A1 (fr) |
| PL (1) | PL365058A1 (fr) |
| WO (1) | WO2002085877A2 (fr) |
| ZA (1) | ZA200308261B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0228410D0 (en) * | 2002-12-05 | 2003-01-08 | Glaxo Group Ltd | Novel Compounds |
| JP2007528400A (ja) | 2004-03-09 | 2007-10-11 | エラン ファーマシューティカルズ，インコーポレイテッド | 置換ヒドロキシエチルアミン系のアスパラギン酸プロテアーゼ阻害薬 |
| EP1773756A2 (fr) | 2004-07-09 | 2007-04-18 | Elan Pharmaceuticals, Inc. | Inhibiteurs d'une aspartyl protease de type hydroxyethylamine substituee par un derive d'oxime |
| WO2007047305A1 (fr) | 2005-10-12 | 2007-04-26 | Elan Pharmaceuticals, Inc. | Procedes de traitement de l'amyloïdose en utilisant des derives de cyclopropyle inhibiteurs de l'aspartyle-protease |
| WO2019168874A1 (fr) | 2018-02-27 | 2019-09-06 | The Research Foundation For The State University Of New York | Compositions de difluorométhoxylation et de trifluorométhoxylation et leurs procédés de synthèse |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2788044B2 (ja) | 1989-02-06 | 1998-08-20 | サントリー株式会社 | マレイミド誘導体およびそれを有効成分として含有する農園芸用殺菌剤 |
| US5583238A (en) | 1990-11-19 | 1996-12-10 | G. D. Searle & Co. | Method for making intermediates useful in synthesis of retroviral protease inhibitors |
| US5482947A (en) | 1990-11-19 | 1996-01-09 | Talley; John J. | Retroviral protease inhibitors |
| US5559256A (en) * | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
| RU2146668C1 (ru) | 1992-08-25 | 2000-03-20 | Джи Ди Сирл энд Компани | Сульфонилалканоиламино-гидроксиэтиламино-сульфонамидное соединение, фармацевтические композиции и способы лечения и ингибирования ретровирусных протеаз |
| US5481011A (en) * | 1994-12-13 | 1996-01-02 | Bristol-Myers Squibb Company | Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters |
| US5985911A (en) * | 1997-01-07 | 1999-11-16 | Abbott Laboratories | C-terminal ketone inhibitors of matrix metalloproteinases and TNFα secretion |
| CA2280096A1 (fr) * | 1997-02-04 | 1998-08-06 | The Regents Of The University Of California | Inhibiteurs de cathepsine d nanomolaires et non peptidiques |
| CA2273643A1 (fr) | 1998-06-09 | 1999-12-09 | F. Hoffmann-La Roche Ag | Reduction stereoselective de composes carbonyles |
| US7119085B2 (en) | 2000-03-23 | 2006-10-10 | Elan Pharmaceuticals, Inc. | Methods to treat alzheimer's disease |
| US7034182B2 (en) * | 2000-06-30 | 2006-04-25 | Elan Pharmaceuticals, Inc. | Compounds to treat Alzheimer's disease |
| PE20020276A1 (es) | 2000-06-30 | 2002-04-06 | Elan Pharm Inc | COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER |
| US6846813B2 (en) | 2000-06-30 | 2005-01-25 | Pharmacia & Upjohn Company | Compounds to treat alzheimer's disease |
| US20030096864A1 (en) | 2000-06-30 | 2003-05-22 | Fang Lawrence Y. | Compounds to treat alzheimer's disease |
| BR0214736A (pt) | 2001-12-06 | 2004-11-23 | Elan Pharm Inc | Composto e seus sais farmaceuticamente aceitáveis, composição farmacêutica e método de tratar seres humanos ou animais que sofrem de doenças ou condições |
-
2002
- 2002-04-19 AR ARP020101444A patent/AR035960A1/es unknown
- 2002-04-23 EA EA200301133A patent/EA007535B1/ru not_active IP Right Cessation
- 2002-04-23 CN CNA02812636XA patent/CN1612871A/zh active Pending
- 2002-04-23 PE PE2002000343A patent/PE20021068A1/es not_active Application Discontinuation
- 2002-04-23 MX MXPA03009723A patent/MXPA03009723A/es active IP Right Grant
- 2002-04-23 EP EP02728882A patent/EP1381597B1/fr not_active Expired - Lifetime
- 2002-04-23 AT AT02728882T patent/ATE401299T1/de not_active IP Right Cessation
- 2002-04-23 US US10/128,122 patent/US6849750B2/en not_active Expired - Fee Related
- 2002-04-23 AP APAP/P/2003/002897A patent/AP2003002897A0/en unknown
- 2002-04-23 NZ NZ529169A patent/NZ529169A/en unknown
- 2002-04-23 WO PCT/US2002/012591 patent/WO2002085877A2/fr active IP Right Grant
- 2002-04-23 JP JP2002583404A patent/JP2004529152A/ja active Pending
- 2002-04-23 KR KR10-2003-7013902A patent/KR20040047750A/ko not_active Application Discontinuation
- 2002-04-23 DE DE60227652T patent/DE60227652D1/de not_active Expired - Fee Related
- 2002-04-23 OA OA1200300276A patent/OA12597A/en unknown
- 2002-04-23 PL PL02365058A patent/PL365058A1/xx not_active Application Discontinuation
- 2002-04-23 IL IL15858502A patent/IL158585A0/xx unknown
- 2002-04-23 CA CA002445163A patent/CA2445163A1/fr not_active Abandoned
- 2002-04-23 ES ES02728882T patent/ES2309170T3/es not_active Expired - Lifetime
- 2002-04-23 BR BR0209163-1A patent/BR0209163A/pt not_active IP Right Cessation
-
2003
- 2003-10-23 IL IL158585A patent/IL158585A/en not_active IP Right Cessation
- 2003-10-23 NO NO20034738A patent/NO20034738L/no not_active Application Discontinuation
- 2003-10-23 ZA ZA200308261A patent/ZA200308261B/en unknown
- 2003-11-20 CO CO03102567A patent/CO5650163A2/es not_active Application Discontinuation
-
2005
- 2005-02-01 US US11/048,389 patent/US7638646B2/en not_active Expired - Fee Related
-
2009
- 2009-12-23 US US12/646,526 patent/US20100099898A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR035960A1 (es) | 2004-07-28 |
| NO20034738L (no) | 2003-12-04 |
| CN1612871A (zh) | 2005-05-04 |
| US6849750B2 (en) | 2005-02-01 |
| ZA200308261B (en) | 2004-05-24 |
| US20100099898A1 (en) | 2010-04-22 |
| NZ529169A (en) | 2005-06-24 |
| ATE401299T1 (de) | 2008-08-15 |
| PE20021068A1 (es) | 2002-12-11 |
| US20030004360A1 (en) | 2003-01-02 |
| KR20040047750A (ko) | 2004-06-05 |
| AP2003002897A0 (en) | 2003-12-31 |
| WO2002085877A3 (fr) | 2003-03-06 |
| PL365058A1 (en) | 2004-12-27 |
| NO20034738D0 (no) | 2003-10-23 |
| EA200301133A1 (ru) | 2004-04-29 |
| IL158585A (en) | 2009-06-15 |
| EP1381597A2 (fr) | 2004-01-21 |
| ES2309170T3 (es) | 2008-12-16 |
| EA007535B1 (ru) | 2006-10-27 |
| BR0209163A (pt) | 2004-08-24 |
| CA2445163A1 (fr) | 2002-10-31 |
| JP2004529152A (ja) | 2004-09-24 |
| DE60227652D1 (de) | 2008-08-28 |
| IL158585A0 (en) | 2004-05-12 |
| US20050130936A1 (en) | 2005-06-16 |
| WO2002085877A2 (fr) | 2002-10-31 |
| EP1381597B1 (fr) | 2008-07-16 |
| CO5650163A2 (es) | 2006-06-30 |
| MXPA03009723A (es) | 2004-03-16 |
| US7638646B2 (en) | 2009-12-29 |
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