OA08583A - Naphtyridine aryl-substituée et dérivés de pyridopyrazine. - Google Patents

Naphtyridine aryl-substituée et dérivés de pyridopyrazine.

Info

Publication number
OA08583A
OA08583A OA59104A OA59104A OA08583A OA 08583 A OA08583 A OA 08583A OA 59104 A OA59104 A OA 59104A OA 59104 A OA59104 A OA 59104A OA 08583 A OA08583 A OA 08583A
Authority
OA
OAPI
Prior art keywords
aryl
disclosed
substituted naphthyridine
pyridopyrazine derivatives
substituted
Prior art date
Application number
OA59104A
Other languages
English (en)
Inventor
David John Blythin
Ho-Jane Shue
Marvin Ira Siegel
Sidney Randall Smith
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/921,288 external-priority patent/US4882332A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of OA08583A publication Critical patent/OA08583A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
OA59104A 1986-04-11 1987-04-10 Naphtyridine aryl-substituée et dérivés de pyridopyrazine. OA08583A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85106886A 1986-04-11 1986-04-11
US06/921,288 US4882332A (en) 1986-10-20 1986-10-20 Immune suppression method employing arly-substituted naphthyridine and pyridopyrazine derivatives

Publications (1)

Publication Number Publication Date
OA08583A true OA08583A (fr) 1988-09-30

Family

ID=27126973

Family Applications (1)

Application Number Title Priority Date Filing Date
OA59104A OA08583A (fr) 1986-04-11 1987-04-10 Naphtyridine aryl-substituée et dérivés de pyridopyrazine.

Country Status (16)

Country Link
EP (1) EP0241291B1 (fr)
JP (1) JPH0774215B2 (fr)
KR (1) KR870010049A (fr)
AT (1) ATE90096T1 (fr)
AU (1) AU609389B2 (fr)
CA (1) CA1324381C (fr)
DE (1) DE3786036T2 (fr)
DK (1) DK186487A (fr)
ES (1) ES2054665T3 (fr)
FI (1) FI88033C (fr)
HU (1) HU200768B (fr)
IL (1) IL82150A0 (fr)
NO (1) NO165923C (fr)
NZ (1) NZ219931A (fr)
OA (1) OA08583A (fr)
PT (1) PT84658B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK127086A (da) * 1985-03-25 1986-09-26 Schering Corp Substituerede 1,8-naphthyridoner, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner, der indeholder disse forbindelser
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
AU2009333653B2 (en) * 2008-12-17 2015-09-10 Merck Patent Gmbh C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents
DE3481418D1 (de) * 1983-12-14 1990-04-05 Schering Corp Substituierte spiropyridinderivate, diese enthaltende pharmazeutische zubereitungen, verfahren zu ihrer herstellung und zubereitungen.
DK127086A (da) * 1985-03-25 1986-09-26 Schering Corp Substituerede 1,8-naphthyridoner, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner, der indeholder disse forbindelser
US4596809A (en) * 1985-03-25 1986-06-24 Schering Corporation Substituted 1,8-naphthyridinones, useful as anti-allergic agents

Also Published As

Publication number Publication date
JPS62270582A (ja) 1987-11-24
PT84658A (en) 1987-05-01
DK186487D0 (da) 1987-04-10
FI88033B (fi) 1992-12-15
IL82150A0 (en) 1987-10-30
JPH0774215B2 (ja) 1995-08-09
NO871507D0 (no) 1987-04-10
KR870010049A (ko) 1987-11-30
ES2054665T3 (es) 1994-08-16
DK186487A (da) 1987-10-12
DE3786036T2 (de) 1993-09-09
NZ219931A (en) 1989-10-27
EP0241291A2 (fr) 1987-10-14
HUT43847A (en) 1987-12-28
AU7135887A (en) 1987-10-15
CA1324381C (fr) 1993-11-16
AU609389B2 (en) 1991-05-02
PT84658B (pt) 1989-11-30
EP0241291B1 (fr) 1993-06-02
FI871568A0 (fi) 1987-04-09
FI88033C (fi) 1993-03-25
NO165923C (no) 1991-05-02
FI871568A (fi) 1987-10-12
DE3786036D1 (de) 1993-07-08
EP0241291A3 (en) 1989-05-31
NO165923B (no) 1991-01-21
NO871507L (no) 1987-10-12
HU200768B (en) 1990-08-28
ATE90096T1 (de) 1993-06-15

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