OA08469A - Dérivés de benzazécine. - Google Patents
Dérivés de benzazécine.Info
- Publication number
- OA08469A OA08469A OA59052A OA59052A OA08469A OA 08469 A OA08469 A OA 08469A OA 59052 A OA59052 A OA 59052A OA 59052 A OA59052 A OA 59052A OA 08469 A OA08469 A OA 08469A
- Authority
- OA
- OAPI
- Prior art keywords
- chloro
- cpds
- acetyl
- benzazecine
- methoxybenzoyl
- Prior art date
Links
- LOLJNNQHTPVJJR-UHFFFAOYSA-N 1-benzazecine Chemical class N1=CC=CC=CC=CC2=CC=CC=C21 LOLJNNQHTPVJJR-UHFFFAOYSA-N 0.000 title abstract 2
- -1 chloro benzoyl Chemical group 0.000 abstract 3
- WZJYKHNJTSNBHV-UHFFFAOYSA-N benzo[h]quinoline Chemical compound C1=CN=C2C3=CC=CC=C3C=CC2=C1 WZJYKHNJTSNBHV-UHFFFAOYSA-N 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- NWJFECNBGMVGDV-UHFFFAOYSA-N 4-acetyl-9-chloro-2,5,6,7-tetrahydro-1h-4-benzazecine-3,8-dione Chemical compound C1CC(=O)N(C(=O)C)CCCC(=O)C2=C(Cl)C=CC=C21 NWJFECNBGMVGDV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
- C07D227/02—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D227/06—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D227/08—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH26686 | 1986-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA08469A true OA08469A (fr) | 1988-07-29 |
Family
ID=4183090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA59052A OA08469A (fr) | 1986-01-23 | 1987-01-23 | Dérivés de benzazécine. |
Country Status (30)
| Country | Link |
|---|---|
| US (4) | US4732979A (cs) |
| EP (1) | EP0230967B1 (cs) |
| JP (1) | JPS62169770A (cs) |
| KR (1) | KR910000659B1 (cs) |
| CN (1) | CN1013111B (cs) |
| AT (1) | ATE68790T1 (cs) |
| AU (1) | AU590042B2 (cs) |
| CS (1) | CS258147B2 (cs) |
| DD (1) | DD264431A5 (cs) |
| DE (1) | DE3773950D1 (cs) |
| DK (1) | DK35887A (cs) |
| FI (1) | FI82931C (cs) |
| GB (1) | GB2185744B (cs) |
| HU (1) | HU197883B (cs) |
| IE (1) | IE870167L (cs) |
| IL (1) | IL81317A (cs) |
| IS (1) | IS3190A7 (cs) |
| MC (1) | MC1795A1 (cs) |
| MT (1) | MTP996B (cs) |
| MW (1) | MW187A1 (cs) |
| NO (1) | NO167385C (cs) |
| NZ (1) | NZ218987A (cs) |
| OA (1) | OA08469A (cs) |
| PH (1) | PH22879A (cs) |
| PL (1) | PL263796A1 (cs) |
| PT (1) | PT84181B (cs) |
| TN (1) | TNSN87006A1 (cs) |
| YU (1) | YU7087A (cs) |
| ZA (1) | ZA87407B (cs) |
| ZW (1) | ZW1087A1 (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI82931C (fi) * | 1986-01-23 | 1991-05-10 | Hoffmann La Roche | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensazecinderivat. |
| IN167395B (cs) * | 1987-07-21 | 1990-10-20 | Hoffmann La Roche | |
| EP0591583B1 (en) * | 1991-08-21 | 2001-12-19 | Eli Lilly And Company | Benzo (f) quinolinones as 5-alpha-reductase inhibitors |
| ES2125884T3 (es) * | 1991-08-21 | 1999-03-16 | Lilly Co Eli | Hexahidrobenzo(f)quinolinonas como inhibidores de la 5-alfa-reductasa. |
| US5239075A (en) * | 1991-08-21 | 1993-08-24 | Eli Lilly And Company | Process for the preparation of benzo (f) quinolinones |
| US5250539A (en) * | 1991-08-21 | 1993-10-05 | Eli Lilly And Company | Hexahydrobenzo[f]quinolinones |
| WO1994022444A1 (en) * | 1993-03-29 | 1994-10-13 | Smithkline Beecham Corporation | Tricyclic compounds for inhibiting platelet aggregation |
| GB9317314D0 (en) * | 1993-08-20 | 1993-10-06 | Smithkline Beecham Corp | Compounds |
| KR970706271A (ko) | 1994-09-20 | 1997-11-03 | 스티븐슨 린다 에스. | 시냅스 전달 향상용 약제(drugs to improve synaptic transmission) |
| US20050067341A1 (en) * | 2003-09-25 | 2005-03-31 | Green Dennis H. | Continuous production membrane water treatment plant and method for operating same |
| US7094331B2 (en) * | 2003-11-05 | 2006-08-22 | Marathon Ashland Petroleum Llc | Viscosity modification of heavy hydrocarbons using dihydric alcohols |
| US20090263439A1 (en) * | 2008-04-18 | 2009-10-22 | The Procter & Gamble Company | Antimicrobial Preservative Free Wipe |
| CN106117028B (zh) * | 2016-06-14 | 2019-01-01 | 浙江永太药业有限公司 | 一种制备卤代-3,4-二氢-1h-2-萘酮的工艺方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE442586A (cs) * | 1940-07-31 | |||
| JPS5129710B2 (cs) * | 1972-09-09 | 1976-08-27 | ||
| US4341786A (en) * | 1981-03-02 | 1982-07-27 | Smithkline Corporation | Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds |
| US4521423A (en) * | 1983-10-31 | 1985-06-04 | Ayerst, Mckenna & Harrison, Ltd. | 7,8,9,10-Tetrahydrobenzo[h]quinolin-9-amine derivatives and compositions and methods for treating depression employing them |
| FI82931C (fi) * | 1986-01-23 | 1991-05-10 | Hoffmann La Roche | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensazecinderivat. |
-
1987
- 1987-01-20 FI FI870220A patent/FI82931C/fi not_active IP Right Cessation
- 1987-01-20 IL IL81317A patent/IL81317A/xx unknown
- 1987-01-20 CS CS87418A patent/CS258147B2/cs unknown
- 1987-01-20 NZ NZ218987A patent/NZ218987A/en unknown
- 1987-01-20 MW MW1/87A patent/MW187A1/xx unknown
- 1987-01-20 EP EP87100733A patent/EP0230967B1/de not_active Expired - Lifetime
- 1987-01-20 ZA ZA87407A patent/ZA87407B/xx unknown
- 1987-01-20 DE DE8787100733T patent/DE3773950D1/de not_active Expired - Lifetime
- 1987-01-20 YU YU00070/87A patent/YU7087A/xx unknown
- 1987-01-20 PH PH34744A patent/PH22879A/en unknown
- 1987-01-20 AT AT87100733T patent/ATE68790T1/de not_active IP Right Cessation
- 1987-01-21 US US07/005,712 patent/US4732979A/en not_active Expired - Fee Related
- 1987-01-21 ZW ZW10/87A patent/ZW1087A1/xx unknown
- 1987-01-21 HU HU87163A patent/HU197883B/hu not_active IP Right Cessation
- 1987-01-21 DD DD87299380A patent/DD264431A5/de unknown
- 1987-01-22 IE IE870167A patent/IE870167L/xx unknown
- 1987-01-22 AU AU67911/87A patent/AU590042B2/en not_active Ceased
- 1987-01-22 PT PT84181A patent/PT84181B/pt not_active IP Right Cessation
- 1987-01-22 GB GB8701416A patent/GB2185744B/en not_active Expired
- 1987-01-22 DK DK035887A patent/DK35887A/da not_active Application Discontinuation
- 1987-01-22 MT MT996A patent/MTP996B/xx unknown
- 1987-01-22 MC MC871868A patent/MC1795A1/fr unknown
- 1987-01-22 CN CN87100312A patent/CN1013111B/zh not_active Expired
- 1987-01-22 NO NO870280A patent/NO167385C/no unknown
- 1987-01-22 JP JP62011477A patent/JPS62169770A/ja active Pending
- 1987-01-22 TN TNTNSN87006A patent/TNSN87006A1/fr unknown
- 1987-01-22 IS IS3190A patent/IS3190A7/is unknown
- 1987-01-23 KR KR1019870000533A patent/KR910000659B1/ko not_active Expired
- 1987-01-23 PL PL1987263796A patent/PL263796A1/xx unknown
- 1987-01-23 OA OA59052A patent/OA08469A/xx unknown
- 1987-11-18 US US07/121,987 patent/US4749791A/en not_active Expired - Fee Related
-
1988
- 1988-02-11 US US07/154,760 patent/US4876340A/en not_active Expired - Fee Related
-
1989
- 1989-08-17 US US07/395,380 patent/US4957911A/en not_active Expired - Fee Related
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