PT84181A - Process for the preparation of benzazecine derivatives and of pharmaceutical compositions containing the same - Google Patents

Process for the preparation of benzazecine derivatives and of pharmaceutical compositions containing the same

Info

Publication number
PT84181A
PT84181A PT84181A PT8418187A PT84181A PT 84181 A PT84181 A PT 84181A PT 84181 A PT84181 A PT 84181A PT 8418187 A PT8418187 A PT 8418187A PT 84181 A PT84181 A PT 84181A
Authority
PT
Portugal
Prior art keywords
chloro
preparation
same
benzazecine
pharmaceutical compositions
Prior art date
Application number
PT84181A
Other languages
English (en)
Other versions
PT84181B (pt
Inventor
Werner Aschwanden
Rene Inhof
Roland Jakob
Emilio Kyburz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT84181A publication Critical patent/PT84181A/pt
Publication of PT84181B publication Critical patent/PT84181B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D227/00Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
    • C07D227/02Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D227/06Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D227/08Oxygen atoms
PT84181A 1986-01-23 1987-01-22 Processo para a preparacao de derivados de benzazecina e de composicoes farmaceuticas que os comtem PT84181B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH26686 1986-01-23

Publications (2)

Publication Number Publication Date
PT84181A true PT84181A (pt) 1987-02-01
PT84181B PT84181B (pt) 1989-09-14

Family

ID=4183090

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84181A PT84181B (pt) 1986-01-23 1987-01-22 Processo para a preparacao de derivados de benzazecina e de composicoes farmaceuticas que os comtem

Country Status (30)

Country Link
US (4) US4732979A (pt)
EP (1) EP0230967B1 (pt)
JP (1) JPS62169770A (pt)
KR (1) KR910000659B1 (pt)
CN (1) CN1013111B (pt)
AT (1) ATE68790T1 (pt)
AU (1) AU590042B2 (pt)
CS (1) CS258147B2 (pt)
DD (1) DD264431A5 (pt)
DE (1) DE3773950D1 (pt)
DK (1) DK35887A (pt)
FI (1) FI82931C (pt)
GB (1) GB2185744B (pt)
HU (1) HU197883B (pt)
IE (1) IE870167L (pt)
IL (1) IL81317A (pt)
IS (1) IS3190A7 (pt)
MC (1) MC1795A1 (pt)
MT (1) MTP996B (pt)
MW (1) MW187A1 (pt)
NO (1) NO167385C (pt)
NZ (1) NZ218987A (pt)
OA (1) OA08469A (pt)
PH (1) PH22879A (pt)
PL (1) PL263796A1 (pt)
PT (1) PT84181B (pt)
TN (1) TNSN87006A1 (pt)
YU (1) YU7087A (pt)
ZA (1) ZA87407B (pt)
ZW (1) ZW1087A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI82931C (fi) * 1986-01-23 1991-05-10 Hoffmann La Roche Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensazecinderivat.
IN167395B (pt) * 1987-07-21 1990-10-20 Hoffmann La Roche
EP0591583B1 (en) * 1991-08-21 2001-12-19 Eli Lilly And Company Benzo (f) quinolinones as 5-alpha-reductase inhibitors
US5250539A (en) * 1991-08-21 1993-10-05 Eli Lilly And Company Hexahydrobenzo[f]quinolinones
ES2125884T3 (es) * 1991-08-21 1999-03-16 Lilly Co Eli Hexahidrobenzo(f)quinolinonas como inhibidores de la 5-alfa-reductasa.
US5239075A (en) * 1991-08-21 1993-08-24 Eli Lilly And Company Process for the preparation of benzo (f) quinolinones
WO1994022444A1 (en) * 1993-03-29 1994-10-13 Smithkline Beecham Corporation Tricyclic compounds for inhibiting platelet aggregation
GB9317314D0 (en) * 1993-08-20 1993-10-06 Smithkline Beecham Corp Compounds
ES2143068T3 (es) 1994-09-20 2000-05-01 Univ California Brefeldina a y analogos para la transmision sinaptica mejorada.
US20050067341A1 (en) * 2003-09-25 2005-03-31 Green Dennis H. Continuous production membrane water treatment plant and method for operating same
US7094331B2 (en) * 2003-11-05 2006-08-22 Marathon Ashland Petroleum Llc Viscosity modification of heavy hydrocarbons using dihydric alcohols
US20090263439A1 (en) * 2008-04-18 2009-10-22 The Procter & Gamble Company Antimicrobial Preservative Free Wipe
CN106117028B (zh) * 2016-06-14 2019-01-01 浙江永太药业有限公司 一种制备卤代-3,4-二氢-1h-2-萘酮的工艺方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE442586A (pt) * 1940-07-31
JPS5129710B2 (pt) * 1972-09-09 1976-08-27
US4341786A (en) * 1981-03-02 1982-07-27 Smithkline Corporation Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds
US4521423A (en) * 1983-10-31 1985-06-04 Ayerst, Mckenna & Harrison, Ltd. 7,8,9,10-Tetrahydrobenzo[h]quinolin-9-amine derivatives and compositions and methods for treating depression employing them
FI82931C (fi) * 1986-01-23 1991-05-10 Hoffmann La Roche Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensazecinderivat.

Also Published As

Publication number Publication date
MTP996B (en) 1987-08-21
GB2185744B (en) 1989-12-06
PL263796A1 (en) 1988-10-27
FI82931B (fi) 1991-01-31
OA08469A (fr) 1988-07-29
DD264431A5 (de) 1989-02-01
US4749791A (en) 1988-06-07
TNSN87006A1 (fr) 1990-01-01
KR910000659B1 (ko) 1991-01-31
DE3773950D1 (de) 1991-11-28
IL81317A (en) 1991-06-30
NO167385C (no) 1991-10-30
HU197883B (en) 1989-06-28
AU6791187A (en) 1987-07-30
US4732979A (en) 1988-03-22
CN1013111B (zh) 1991-07-10
EP0230967A3 (en) 1988-08-31
US4876340A (en) 1989-10-24
ZW1087A1 (en) 1987-08-12
GB8701416D0 (en) 1987-02-25
PT84181B (pt) 1989-09-14
ATE68790T1 (de) 1991-11-15
DK35887A (da) 1987-07-24
FI870220A0 (fi) 1987-01-20
GB2185744A (en) 1987-07-29
CS41887A2 (en) 1987-11-12
YU7087A (en) 1988-06-30
NO870280D0 (no) 1987-01-22
PH22879A (en) 1989-01-19
US4957911A (en) 1990-09-18
AU590042B2 (en) 1989-10-26
NO167385B (no) 1991-07-22
MW187A1 (en) 1987-10-14
IE870167L (en) 1987-07-23
NO870280L (no) 1987-07-24
NZ218987A (en) 1990-04-26
MC1795A1 (fr) 1987-10-22
FI870220A (fi) 1987-07-24
IL81317A0 (en) 1987-08-31
CN87100312A (zh) 1987-09-09
CS258147B2 (en) 1988-07-15
HUT44519A (en) 1988-03-28
DK35887D0 (da) 1987-01-22
FI82931C (fi) 1991-05-10
KR870007132A (ko) 1987-08-17
JPS62169770A (ja) 1987-07-25
EP0230967B1 (de) 1991-10-23
ZA87407B (en) 1987-09-30
EP0230967A2 (de) 1987-08-05
IS3190A7 (is) 1987-07-24

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19920831