LU88822I2 - Stavudine et ses dérivés pharmaceutiquement acceptables (Zerit R) - Google Patents

Stavudine et ses dérivés pharmaceutiquement acceptables (Zerit R)

Info

Publication number
LU88822I2
LU88822I2 LU88822C LU88822C LU88822I2 LU 88822 I2 LU88822 I2 LU 88822I2 LU 88822 C LU88822 C LU 88822C LU 88822 C LU88822 C LU 88822C LU 88822 I2 LU88822 I2 LU 88822I2
Authority
LU
Luxembourg
Prior art keywords
zerit
stavudine
pharmaceutically acceptable
acceptable derivatives
derivatives
Prior art date
Application number
LU88822C
Other languages
English (en)
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25478432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU88822(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Yale filed Critical Univ Yale
Publication of LU88822I2 publication Critical patent/LU88822I2/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LU88822C 1986-12-17 1987-12-11 Stavudine et ses dérivés pharmaceutiquement acceptables (Zerit R) LU88822I2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/942,666 US4978655A (en) 1986-12-17 1986-12-17 Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses

Publications (1)

Publication Number Publication Date
LU88822I2 true LU88822I2 (fr) 1997-01-06

Family

ID=25478432

Family Applications (1)

Application Number Title Priority Date Filing Date
LU88822C LU88822I2 (fr) 1986-12-17 1987-12-11 Stavudine et ses dérivés pharmaceutiquement acceptables (Zerit R)

Country Status (22)

Country Link
US (1) US4978655A (fr)
EP (1) EP0273277B1 (fr)
JP (1) JPH07116041B2 (fr)
KR (1) KR960000433B1 (fr)
AT (1) ATE77554T1 (fr)
AU (1) AU593405B2 (fr)
CA (1) CA1293447C (fr)
DE (1) DE3780016T2 (fr)
DK (1) DK174627B1 (fr)
EG (1) EG19157A (fr)
ES (1) ES2038650T3 (fr)
FI (1) FI875544A (fr)
GR (1) GR3005691T3 (fr)
HK (1) HK55896A (fr)
IE (1) IE60866B1 (fr)
IL (1) IL84790A (fr)
LU (1) LU88822I2 (fr)
NL (1) NL960024I2 (fr)
NZ (1) NZ222935A (fr)
PH (1) PH26380A (fr)
PT (1) PT86346B (fr)
ZA (1) ZA877171B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5175292A (en) * 1988-01-20 1992-12-29 Regents Of The University Of Minnesota Intermediates for the preparation of dideoxycarbocyclic nucleosides
FI95269C (fi) * 1989-05-15 1996-01-10 Squibb Bristol Myers Co 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja
US6207650B1 (en) 1989-05-15 2001-03-27 Bristol-Myers Squibb Company Antiviral, highly water soluble, stable, crystalline salts of 2′, 3′-dideoxyinosine, 2′, 3′-dideoxy-2′, 3′-didehydrothymidine and 2′, 3′-dideoxy-2′-fluoroinosine
US5608048A (en) * 1995-06-05 1997-03-04 Bristol-Myers Squibb Company d4 T polymorphic Form 1 process
US5840711A (en) * 1995-06-21 1998-11-24 University Of Kentucky Research Foundation Compositions containing lithium inorganic salts and anti-viral drugs and method of treating viral infections such as acquired immunodeficiency syndrome
CA2189097A1 (fr) 1995-11-15 1997-05-16 Pin-Fang Lin Composition et methode pour le traitement de l'infection retrovirale
US5719132A (en) * 1996-06-27 1998-02-17 Bristol-Myers Squibb Company Compositions and methods of treating HIV with d4T, 5-fluorouracil/tegafur, and uracil
WO2000016625A1 (fr) * 1998-09-23 2000-03-30 University Of Kentucky Research Foundation Compositions medicamenteuses antivirales contenant des sels inorganiques de lithium
CA2404687A1 (fr) 2000-03-30 2001-10-11 Nemichand B. Jain Granules a liberation lente contenant de la stavudine
EP1490090A4 (fr) 2002-02-22 2006-09-20 New River Pharmaceuticals Inc Systemes de distribution d'agents actifs et methodes de protection et d'administration d'agents actifs
WO2005011709A1 (fr) * 2003-02-19 2005-02-10 Yale University Analogues de nucleosides antiviraux et methodes de traitement d'infections virales, notamment d'infections a vih
US20040200730A1 (en) * 2003-04-14 2004-10-14 Kyo Jibiki Hydrometallurgical copper recovery process
EP3539546A1 (fr) 2004-07-27 2019-09-18 Gilead Sciences, Inc. Analogues phosphanate de composés inhibiteurs du vih
KR20080053317A (ko) * 2005-08-31 2008-06-12 씨아이피엘에이 엘티디. 라미부딘, 스타부딘 및 네비라핀을 포함하는 약학적 조합물
SG172060A1 (en) 2008-12-09 2011-07-28 Gilead Sciences Inc Modulators of toll-like receptors
US20110223131A1 (en) 2010-02-24 2011-09-15 Gilead Sciences, Inc. Antiviral compounds
WO2016001907A1 (fr) 2014-07-02 2016-01-07 Prendergast Patrick T Mogroside iv et mogroside v utilisables en tant qu'agonistes/stimulateurs/agents de déblocage des récepteurs toll 4 et adjuvant destiné à être utilisé dans un vaccin humain/animal et pour stimuler l'immunité contre des agents pathologiques
SG11201700070QA (en) 2014-07-11 2017-02-27 Gilead Sciences Inc Modulators of toll-like receptors for the treatment of hiv
CA2997955A1 (fr) 2015-09-15 2017-03-23 Gilead Sciences, Inc. Modulateurs de recepteurs de type toll pour le traitement du vih

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3322747A (en) * 1965-04-01 1967-05-30 Merck & Co Inc Thionocarbonate nucleosides
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
JPS5943550B2 (ja) * 1975-08-29 1984-10-23 田辺製薬株式会社 不飽和ヌクレオシドの製法
DE3515870A1 (de) * 1985-05-03 1986-11-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 5-fluortoluol-2,4-disulfochlorid
US4710492A (en) * 1986-06-23 1987-12-01 Yale University 3'-azido-2',3'-dideoxy-5-halouridine and its use in treating patients infected with retroviruses
NL8700089A (nl) * 1987-01-15 1988-08-01 Stichting Rega V Z W Therapeutische toepassing van dideoxythymidine en dideoxythymidineen.
DE3806633A1 (de) * 1987-09-01 1989-03-09 Bayer Ag Antivirales mittel
JP2648329B2 (ja) * 1987-09-18 1997-08-27 エフ・ホフマン−ラ ロシュ アーゲー エイズの予防または治療用医薬組成物
SE8704298D0 (sv) * 1987-11-03 1987-11-03 Astra Ab Compounds for use in therapy
JPH0227782A (ja) * 1988-07-15 1990-01-30 Hikari Gijutsu Kenkyu Kaihatsu Kk 半導体発光素子
JPH0438727A (ja) * 1990-06-04 1992-02-07 Sharp Corp 光学式ピックアップ装置の対物レンズ塵埃付着防止機構

Also Published As

Publication number Publication date
ATE77554T1 (de) 1992-07-15
FI875544A (fi) 1988-06-18
PT86346B (pt) 1990-11-07
EP0273277B1 (fr) 1992-06-24
FI875544A0 (fi) 1987-12-16
IE60866B1 (en) 1994-08-24
JPS63215632A (ja) 1988-09-08
EP0273277A2 (fr) 1988-07-06
IL84790A0 (en) 1988-05-31
ZA877171B (en) 1988-03-24
EG19157A (en) 1994-09-29
IL84790A (en) 1993-03-15
NZ222935A (en) 1990-09-26
KR880007079A (ko) 1988-08-26
ES2038650T3 (es) 1993-08-01
IE873245L (en) 1988-06-17
PT86346A (en) 1988-01-01
DE3780016T2 (de) 1992-12-24
DK557087A (da) 1988-06-18
EP0273277A3 (en) 1989-09-13
PH26380A (en) 1992-06-01
DE3780016D1 (de) 1992-07-30
NL960024I2 (nl) 1997-06-02
CA1293447C (fr) 1991-12-24
US4978655A (en) 1990-12-18
JPH07116041B2 (ja) 1995-12-13
DK557087D0 (da) 1987-10-23
AU593405B2 (en) 1990-02-08
AU8090087A (en) 1988-06-23
NL960024I1 (nl) 1996-12-02
KR960000433B1 (ko) 1996-01-06
DK174627B1 (da) 2003-07-28
HK55896A (en) 1996-04-03
GR3005691T3 (fr) 1993-06-07

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