NZ595364A - TISSUE KALLIKREIN FOR THE TREATMENT OF PANCREATIC beta-CELL DYSFUNCTION - Google Patents

TISSUE KALLIKREIN FOR THE TREATMENT OF PANCREATIC beta-CELL DYSFUNCTION

Info

Publication number
NZ595364A
NZ595364A NZ595364A NZ59536410A NZ595364A NZ 595364 A NZ595364 A NZ 595364A NZ 595364 A NZ595364 A NZ 595364A NZ 59536410 A NZ59536410 A NZ 59536410A NZ 595364 A NZ595364 A NZ 595364A
Authority
NZ
New Zealand
Prior art keywords
treatment
cell dysfunction
pancreatic beta
tissue kallikrein
kallikrein
Prior art date
Application number
NZ595364A
Other languages
English (en)
Inventor
Mark Williams
Kevin Richardson
Original Assignee
Diamedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diamedica Inc filed Critical Diamedica Inc
Publication of NZ595364A publication Critical patent/NZ595364A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4853—Kallikrein (3.4.21.34 or 3.4.21.35)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NZ595364A 2009-03-25 2010-03-25 TISSUE KALLIKREIN FOR THE TREATMENT OF PANCREATIC beta-CELL DYSFUNCTION NZ595364A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16317309P 2009-03-25 2009-03-25
PCT/CA2010/000413 WO2010108262A1 (en) 2009-03-25 2010-03-25 TISSUE KALLIKREIN FOR THE TREATMENT OF PANCREATIC β-CELL DYSFUNCTION

Publications (1)

Publication Number Publication Date
NZ595364A true NZ595364A (en) 2013-09-27

Family

ID=42780097

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ595364A NZ595364A (en) 2009-03-25 2010-03-25 TISSUE KALLIKREIN FOR THE TREATMENT OF PANCREATIC beta-CELL DYSFUNCTION

Country Status (8)

Country Link
US (1) US20120070425A1 (enExample)
EP (1) EP2411042A4 (enExample)
JP (1) JP2012521366A (enExample)
CN (1) CN102438648A (enExample)
AU (1) AU2010228068A1 (enExample)
CA (1) CA2756801A1 (enExample)
NZ (1) NZ595364A (enExample)
WO (1) WO2010108262A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ582930A (en) 2007-07-20 2012-11-30 Diamedica Inc Tissue kallikrein for the treatment of diseases associated with amyloid protein
JP2014520119A (ja) * 2011-06-17 2014-08-21 ザ・ジョンズ・ホプキンス・ユニバーシティー インスリン感受性を増大させる方法および糖尿病を処置するための方法
WO2013173923A1 (en) 2012-05-25 2013-11-28 Diamedica, Inc. Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
PT2854841T (pt) 2012-06-04 2017-05-15 Diamedica Inc Isoformas de glicosilação da calicreína 1 em tecido humano
CN104073482A (zh) 2013-12-30 2014-10-01 江苏众红生物工程创药研究院有限公司 聚乙二醇化的组织激肽释放酶及其制备方法和应用
US11857608B2 (en) 2017-03-09 2024-01-02 Diamedica Inc. Dosage forms of tissue kallikrein 1
CN112481268B (zh) * 2021-01-25 2024-01-30 河南大学 一种棉花启动子PGhPGF及其重组载体和应用
CN116135973A (zh) * 2021-11-16 2023-05-19 江苏众红生物工程创药研究院有限公司 低糖基化修饰的激肽原酶及其聚乙二醇修饰物和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5534615A (en) 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
JP2002516261A (ja) * 1998-05-22 2002-06-04 エンターメッド インコーポレイテッド セリンプロテアーゼを利用して内皮細胞増殖を阻害し血管新生を調節するための組成物と方法
CN1228447C (zh) * 2001-02-20 2005-11-23 深圳市人民医院 一种含有人胰腺组织激肽释放酶成熟蛋白基因的重组表达载体
CN100338212C (zh) * 2003-01-29 2007-09-19 中国科学院大连化学物理研究所 人组织激肽释放酶的微囊化细胞及其微囊化方法和应用
JP2008515774A (ja) * 2004-08-03 2008-05-15 ダイアックス コーポレイション ｈＫ１結合タンパク質
CN101094869A (zh) * 2004-08-03 2007-12-26 戴埃克斯有限公司 Hk1结合蛋白
EP2051732A4 (en) * 2006-07-26 2009-10-21 Diamedica Inc DIAGNOSIS AND TREATMENT OF METABOLIC DISORDERS AND METHODS THEREFOR
JP5322935B2 (ja) * 2006-07-31 2013-10-23 アクティベサイト ファーマシューティカルズ インコーポレイティッド 血漿カリクレインの阻害薬
CN101134953B (zh) * 2007-07-02 2011-02-09 广东天普生化医药股份有限公司 重组人胰激肽原酶
CN101255438B (zh) * 2008-04-11 2012-01-25 深圳大学 表达人组织激肽释放酶的转基因莱茵衣藻的构建方法

Also Published As

Publication number Publication date
JP2012521366A (ja) 2012-09-13
WO2010108262A1 (en) 2010-09-30
AU2010228068A1 (en) 2011-10-20
US20120070425A1 (en) 2012-03-22
EP2411042A1 (en) 2012-02-01
CN102438648A (zh) 2012-05-02
CA2756801A1 (en) 2010-09-30
EP2411042A4 (en) 2012-12-12

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 25 MAR 2017 BY COMPUTER PACKAGES INC

Effective date: 20140328

LAPS Patent lapsed