NZ565012A - Particles comprising a releasable dopant therein - Google Patents
Particles comprising a releasable dopant thereinInfo
- Publication number
- NZ565012A NZ565012A NZ565012A NZ56501206A NZ565012A NZ 565012 A NZ565012 A NZ 565012A NZ 565012 A NZ565012 A NZ 565012A NZ 56501206 A NZ56501206 A NZ 56501206A NZ 565012 A NZ565012 A NZ 565012A
- Authority
- NZ
- New Zealand
- Prior art keywords
- particles
- dopant
- hydrophobic
- particle
- emulsion
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims abstract description 400
- 239000002019 doping agent Substances 0.000 title claims abstract description 157
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 220
- 239000000463 material Substances 0.000 claims abstract description 206
- 239000002243 precursor Substances 0.000 claims abstract description 118
- 238000000034 method Methods 0.000 claims abstract description 104
- 239000000839 emulsion Substances 0.000 claims abstract description 85
- 230000008569 process Effects 0.000 claims abstract description 79
- 239000003054 catalyst Substances 0.000 claims abstract description 67
- 239000004094 surface-active agent Substances 0.000 claims description 66
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- 238000006243 chemical reaction Methods 0.000 claims description 36
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 66
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 55
- ZNOCGWVLWPVKAO-UHFFFAOYSA-N trimethoxy(phenyl)silane Chemical compound CO[Si](OC)(OC)C1=CC=CC=C1 ZNOCGWVLWPVKAO-UHFFFAOYSA-N 0.000 description 53
- NKSJNEHGWDZZQF-UHFFFAOYSA-N ethenyl(trimethoxy)silane Chemical compound CO[Si](OC)(OC)C=C NKSJNEHGWDZZQF-UHFFFAOYSA-N 0.000 description 52
- -1 bleaches Chemical class 0.000 description 47
- WYTZZXDRDKSJID-UHFFFAOYSA-N (3-aminopropyl)triethoxysilane Chemical group CCO[Si](OCC)(OCC)CCCN WYTZZXDRDKSJID-UHFFFAOYSA-N 0.000 description 44
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- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 42
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- 239000000377 silicon dioxide Substances 0.000 description 27
- SBRXLTRZCJVAPH-UHFFFAOYSA-N ethyl(trimethoxy)silane Chemical compound CC[Si](OC)(OC)OC SBRXLTRZCJVAPH-UHFFFAOYSA-N 0.000 description 26
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 22
- 125000004432 carbon atom Chemical group C* 0.000 description 22
- 238000001228 spectrum Methods 0.000 description 22
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 21
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- BOTDANWDWHJENH-UHFFFAOYSA-N Tetraethyl orthosilicate Chemical compound CCO[Si](OCC)(OCC)OCC BOTDANWDWHJENH-UHFFFAOYSA-N 0.000 description 19
- NOKUWSXLHXMAOM-UHFFFAOYSA-N hydroxy(phenyl)silicon Chemical class O[Si]C1=CC=CC=C1 NOKUWSXLHXMAOM-UHFFFAOYSA-N 0.000 description 19
- 238000011068 loading method Methods 0.000 description 19
- 238000005406 washing Methods 0.000 description 19
- XMTQQYYKAHVGBJ-UHFFFAOYSA-N 3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA Chemical compound CN(C)C(=O)NC1=CC=C(Cl)C(Cl)=C1 XMTQQYYKAHVGBJ-UHFFFAOYSA-N 0.000 description 18
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- LFQCEHFDDXELDD-UHFFFAOYSA-N tetramethyl orthosilicate Chemical compound CO[Si](OC)(OC)OC LFQCEHFDDXELDD-UHFFFAOYSA-N 0.000 description 16
- 238000003756 stirring Methods 0.000 description 15
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 description 14
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- 239000007788 liquid Substances 0.000 description 14
- 125000000962 organic group Chemical group 0.000 description 14
- 229910000077 silane Inorganic materials 0.000 description 14
- JBTHDAVBDKKSRW-UHFFFAOYSA-N chembl1552233 Chemical compound CC1=CC(C)=CC=C1N=NC1=C(O)C=CC2=CC=CC=C12 JBTHDAVBDKKSRW-UHFFFAOYSA-N 0.000 description 13
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 13
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- 150000004703 alkoxides Chemical class 0.000 description 10
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 9
- 238000003917 TEM image Methods 0.000 description 9
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 9
- 239000002775 capsule Substances 0.000 description 9
- 239000001044 red dye Substances 0.000 description 9
- 125000001424 substituent group Chemical group 0.000 description 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 8
- 238000013270 controlled release Methods 0.000 description 8
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- 238000006460 hydrolysis reaction Methods 0.000 description 8
- 125000003118 aryl group Chemical group 0.000 description 7
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 7
- 238000001035 drying Methods 0.000 description 7
- XWRLQRLQUKZEEU-UHFFFAOYSA-N ethyl(hydroxy)silicon Chemical class CC[Si]O XWRLQRLQUKZEEU-UHFFFAOYSA-N 0.000 description 7
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- 230000035484 reaction time Effects 0.000 description 7
- 150000003839 salts Chemical class 0.000 description 7
- OCQDPIXQTSYZJL-UHFFFAOYSA-N 1,4-bis(butylamino)anthracene-9,10-dione Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C(NCCCC)=CC=C2NCCCC OCQDPIXQTSYZJL-UHFFFAOYSA-N 0.000 description 6
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 6
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- LIVNPJMFVYWSIS-UHFFFAOYSA-N silicon monoxide Inorganic materials [Si-]#[O+] LIVNPJMFVYWSIS-UHFFFAOYSA-N 0.000 description 5
- KBPLFHHGFOOTCA-UHFFFAOYSA-N 1-Octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 description 4
- 102100024406 60S ribosomal protein L15 Human genes 0.000 description 4
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- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 101001117935 Homo sapiens 60S ribosomal protein L15 Proteins 0.000 description 4
- 241000124008 Mammalia Species 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
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- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 4
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- IDOQDZANRZQBTP-UHFFFAOYSA-N 2-[2-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=CC=C1OCCO IDOQDZANRZQBTP-UHFFFAOYSA-N 0.000 description 3
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- SJECZPVISLOESU-UHFFFAOYSA-N 3-trimethoxysilylpropan-1-amine Chemical compound CO[Si](OC)(OC)CCCN SJECZPVISLOESU-UHFFFAOYSA-N 0.000 description 3
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- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
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- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 2
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- 238000001000 micrograph Methods 0.000 description 2
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- NHBRUUFBSBSTHM-UHFFFAOYSA-N n'-[2-(3-trimethoxysilylpropylamino)ethyl]ethane-1,2-diamine Chemical compound CO[Si](OC)(OC)CCCNCCNCCN NHBRUUFBSBSTHM-UHFFFAOYSA-N 0.000 description 2
- 125000001624 naphthyl group Chemical group 0.000 description 2
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- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 238000002428 photodynamic therapy Methods 0.000 description 2
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- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical compound CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 description 2
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- 239000011780 sodium chloride Substances 0.000 description 2
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AU2005903192A AU2005903192A0 (en) | 2005-06-17 | Solid particles comprising a hydrophobic material therein | |
PCT/AU2006/000853 WO2006133519A1 (en) | 2005-06-17 | 2006-06-19 | Particles comprising a releasable dopant therein |
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NZ565012A NZ565012A (en) | 2005-06-17 | 2006-06-19 | Particles comprising a releasable dopant therein |
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WO (1) | WO2006133519A1 (ja) |
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US8883038B2 (en) * | 2006-07-05 | 2014-11-11 | Clarkson University | Syntheses of ultra-bright fluorescent silica particles |
JP5259621B2 (ja) | 2006-12-28 | 2013-08-07 | ダウ・コーニング・コーポレイション | 多核マイクロカプセル |
FR2952368B1 (fr) * | 2009-11-10 | 2012-01-13 | Commissariat Energie Atomique | Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations. |
BR112012014722A2 (pt) | 2009-12-15 | 2015-09-22 | Fmc Corp | "microcápsulas de sílica de liberação sustentada" |
US8889044B2 (en) | 2009-12-18 | 2014-11-18 | Kao Corporation | Method for producing mesoporous silica particles |
JP5603063B2 (ja) * | 2009-12-21 | 2014-10-08 | 花王株式会社 | 複合シリカ粒子の製造方法 |
US9822010B2 (en) * | 2010-01-21 | 2017-11-21 | CoLabs International Corporation | Ceramic encapsulation by use of one or more specialized silanes to template oil in an oil in water emulsion |
US9676620B1 (en) | 2010-03-11 | 2017-06-13 | Clarkson University | Synthesis of ultrabright fluorescent silica particles |
US9192548B2 (en) * | 2010-06-25 | 2015-11-24 | CoLabs International Corporation | Ceramic encapsulation with controlled layering by use of functionalized silanes |
NZ606493A (en) * | 2010-08-16 | 2015-09-25 | Australian Nuclear Science Tec | Particulate substances comprising ceramic particles for delivery of biomolecules |
CN104093754B (zh) | 2011-11-21 | 2017-06-23 | 3M创新有限公司 | 用于储存并递送活性剂的聚合物粒子 |
FR2984755B1 (fr) * | 2011-12-21 | 2014-01-10 | Ge Energy Products France Snc | Procede de rupture en continu d'une emulsion eau dans huile et dispositif correspondant |
AU2013264767A1 (en) * | 2012-05-22 | 2014-11-27 | Laila Pharmaceuticals Pvt. Ltd. | Novel highly bioavailable, water soluble and sustained release nanoformulations of hydrophobic plant derived compounds and extracts |
FR2991990B1 (fr) * | 2012-06-15 | 2015-05-15 | Oreal | Pigment organique enrobe et composition cosmetique |
US9701900B2 (en) | 2012-08-17 | 2017-07-11 | Clarkson University | Methods and systems for the synthesis of ultrabright fluorescent silica particles capable of measuring temperature |
WO2014135443A1 (en) * | 2013-03-07 | 2014-09-12 | Oce-Technologies B.V. | Ink composition |
MY173993A (en) * | 2013-03-15 | 2020-03-03 | Arch Chem Inc | Encapsulation of active ingredients and method of making |
CN105228820B (zh) | 2013-05-17 | 2017-08-29 | 3M创新有限公司 | 反应混合物、多孔粒子以及制备方法 |
WO2014186336A1 (en) | 2013-05-17 | 2014-11-20 | 3M Innovative Properties Company | Release of biologically active agents from polymeric composite particles |
US20160168385A1 (en) * | 2013-07-29 | 2016-06-16 | Sg Ventures Pty Limited | Coated Particles and Method of Coating Particles |
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JP2017503881A (ja) | 2013-12-18 | 2017-02-02 | スリーエム イノベイティブ プロパティズ カンパニー | 分離用の多孔質物品 |
KR101750398B1 (ko) * | 2014-01-02 | 2017-06-23 | 삼성전자주식회사 | 광산란층 제조 방법 |
JP6532949B2 (ja) | 2015-02-17 | 2019-06-19 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 単層歯ホワイトニングシステム |
WO2017015617A1 (en) * | 2015-07-23 | 2017-01-26 | New York University | Self-inflating microcapsules |
BR112018009644A2 (pt) | 2015-11-12 | 2018-11-06 | Graybug Vision Inc | micropartículas agregantes sólidas modificadas na superfície, material injetável, processo para preparação de micropartículas agregantes sólidas modificadas na superfície, método para tratamento de um distúrbio ocular, e, uso de micropartículas agregantes sólidas modificadas na superfície |
EP3440252A4 (en) * | 2016-04-05 | 2019-11-27 | Nanopharma A.S. | NANOFIBREUX MATERIAL CONTAINING CERAMIC PARTICLES COMPRISING A RELEASABLE DOPANT |
EP3535359B1 (en) | 2016-11-03 | 2020-05-13 | Unilever PLC | Laundry treatment compositions comprising perfume and silica microparticles |
US11191745B2 (en) * | 2017-02-03 | 2021-12-07 | City Of Hope | Silica nanoparticle with an insoluble drug |
RU2019133337A (ru) | 2017-03-23 | 2021-04-23 | Грейбуг Вижн, Инк. | Лекарственные средства и композиции для лечения глазных нарушений |
AU2018265415A1 (en) | 2017-05-10 | 2019-10-31 | Graybug Vision, Inc. | Extended release microparticles and suspensions thereof for medical therapy |
CN109911910A (zh) * | 2018-03-27 | 2019-06-21 | 广东工业大学 | 一种可用于乳液稳定的高岭土片及其剥离方法 |
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WO2021138710A1 (en) * | 2020-01-09 | 2021-07-15 | Sg Ventures Pty Limited | Substrate for use in a transdermal patch or dressing |
TWI737303B (zh) * | 2020-05-18 | 2021-08-21 | 國立臺灣大學 | 製造多顆氧化矽顆粒之方法 |
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FR2767064B1 (fr) * | 1997-08-07 | 1999-11-12 | Centre Nat Rech Scient | Procede de liberation d'un principe actif contenu dans une emulsion multiple |
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US6239211B1 (en) * | 2000-01-24 | 2001-05-29 | Dow Corning Corporation | Emulsions containing silicone polymers |
AUPQ573300A0 (en) | 2000-02-21 | 2000-03-16 | Australian Nuclear Science & Technology Organisation | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use |
US6548264B1 (en) | 2000-05-17 | 2003-04-15 | University Of Florida | Coated nanoparticles |
JP2001354820A (ja) | 2000-06-14 | 2001-12-25 | Shiseido Co Ltd | 複合エマルジョン及びこれを配合した化粧料 |
DE10035930A1 (de) | 2000-07-21 | 2002-01-31 | Clariant Gmbh | Feinemulsionen |
DE10044635A1 (de) | 2000-09-08 | 2002-04-04 | Henkel Kgaa | Transparente Wirkstoffkapseln |
DE10102006A1 (de) | 2001-01-18 | 2002-10-02 | Cognis Deutschland Gmbh | Tensidgemisch |
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US20060003012A9 (en) * | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
GB0202853D0 (en) * | 2002-02-07 | 2002-03-27 | Dow Corning | Encapsulation process and encapsulated compositions |
GB0215832D0 (en) * | 2002-07-09 | 2002-08-14 | Akay Galip | Preparation of composite high internal phase emulsion polymerised microporous polymers and their applications |
US7059924B2 (en) | 2002-10-26 | 2006-06-13 | Float Tech Inc. | Personal flotation device |
KR100709015B1 (ko) | 2002-11-13 | 2007-04-18 | (주)아모레퍼시픽 | 지속적 약물방출이 가능한 고분자 미립구 및 그 제조방법 |
US7364754B2 (en) | 2003-01-24 | 2008-04-29 | Research Foundation Of The State University Of New York | Ceramic based nanoparticles for entrapping therapeutic agents for photodynamic therapy and method of using same |
MX2007005775A (es) | 2004-11-15 | 2007-08-15 | Australian Nuclear Science Tec | Particulas solidas provenientes de la desestabilizacion controlada de microemulsiones. |
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CN101242814A (zh) | 2008-08-13 |
KR101340494B1 (ko) | 2013-12-11 |
JP2013199481A (ja) | 2013-10-03 |
JP5605593B2 (ja) | 2014-10-15 |
KR101205481B1 (ko) | 2012-11-27 |
EP1906911A1 (en) | 2008-04-09 |
US9131681B2 (en) | 2015-09-15 |
BRPI0611886B1 (pt) | 2019-05-21 |
US20140322326A1 (en) | 2014-10-30 |
BRPI0611886A2 (pt) | 2010-10-05 |
CA2611606A1 (en) | 2006-12-21 |
WO2006133519A1 (en) | 2006-12-21 |
US9017643B2 (en) | 2015-04-28 |
US8815291B2 (en) | 2014-08-26 |
EP1906911B1 (en) | 2019-09-25 |
CA2611606C (en) | 2016-03-29 |
US20080199523A1 (en) | 2008-08-21 |
BRPI0611886B8 (pt) | 2021-05-25 |
MX2007016050A (es) | 2008-03-10 |
KR20120118075A (ko) | 2012-10-25 |
JP2008546649A (ja) | 2008-12-25 |
JP5388005B2 (ja) | 2014-01-15 |
EP1906911A4 (en) | 2011-06-29 |
US20150004095A1 (en) | 2015-01-01 |
KR20080032084A (ko) | 2008-04-14 |
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