NZ563940A - Immunogens for meningitidis-A vaccines comprising oligosaccharides linked by a phosphonate - Google Patents

Immunogens for meningitidis-A vaccines comprising oligosaccharides linked by a phosphonate

Info

Publication number
NZ563940A
NZ563940A NZ563940A NZ56394006A NZ563940A NZ 563940 A NZ563940 A NZ 563940A NZ 563940 A NZ563940 A NZ 563940A NZ 56394006 A NZ56394006 A NZ 56394006A NZ 563940 A NZ563940 A NZ 563940A
Authority
NZ
New Zealand
Prior art keywords
oligosaccharide
mannose
protein
unit
linkage
Prior art date
Application number
NZ563940A
Other languages
English (en)
Inventor
Stefan Oscarson
Peter Teodorovic
Paolo Costantino
Original Assignee
Novartis Vaccines & Diagnostic
Stefan Oscarson
Peter Teodorovic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36942242&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ563940(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines & Diagnostic, Stefan Oscarson, Peter Teodorovic filed Critical Novartis Vaccines & Diagnostic
Publication of NZ563940A publication Critical patent/NZ563940A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
NZ563940A 2005-05-06 2006-05-08 Immunogens for meningitidis-A vaccines comprising oligosaccharides linked by a phosphonate NZ563940A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67828905P 2005-05-06 2005-05-06
PCT/IB2006/001703 WO2006120576A2 (en) 2005-05-06 2006-05-08 Immunogens for meningitidis-a vaccines

Publications (1)

Publication Number Publication Date
NZ563940A true NZ563940A (en) 2010-11-26

Family

ID=36942242

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ563940A NZ563940A (en) 2005-05-06 2006-05-08 Immunogens for meningitidis-A vaccines comprising oligosaccharides linked by a phosphonate

Country Status (15)

Country Link
US (1) US8062641B2 (https=)
EP (1) EP1885734B1 (https=)
JP (2) JP2008540398A (https=)
CN (1) CN101282984B (https=)
AU (1) AU2006245440B2 (https=)
BR (1) BRPI0611447A2 (https=)
CA (1) CA2606890C (https=)
ES (1) ES2533248T3 (https=)
MX (1) MX2007013881A (https=)
NZ (1) NZ563940A (https=)
PL (1) PL1885734T3 (https=)
PT (1) PT1885734E (https=)
RU (1) RU2412944C2 (https=)
WO (1) WO2006120576A2 (https=)
ZA (1) ZA200710558B (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
PE20110072A1 (es) * 2005-06-27 2011-02-04 Glaxosmithkline Biolog Sa Composicion inmunogenica
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
AU2014200640B2 (en) * 2007-01-11 2016-06-16 Glaxosmithkline Biologicals Sa Modified saccharides
GB0700562D0 (en) * 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
KR101646960B1 (ko) 2007-10-16 2016-08-09 프로젠 피지500 시리즈 피티와이 리미티드 신규한 황산화된 올리고사카라이드 유도체
CN107913396B (zh) 2010-08-23 2022-03-08 惠氏有限责任公司 脑膜炎萘瑟氏菌rLP2086抗原的稳定制剂
EP2612148B1 (en) 2010-09-04 2019-06-12 GlaxoSmithKline Biologicals SA Bactericidal antibody assays to assess immunogenicity and potency of meningococcal capsular saccharide vaccines
AU2011300409B2 (en) 2010-09-10 2015-03-26 Wyeth Llc Non-lipidated variants of Neisseria meningitidis ORF2086 antigens
CN102417521B (zh) * 2010-09-28 2014-05-07 中国医学科学院医药生物技术研究所 一种非环核苷类抗病毒药物磷酸单酯化合物的制备方法
WO2012103444A2 (en) * 2011-01-28 2012-08-02 Purdue Research Foundation Immunogenic compositions and reagents for preparing
WO2013009826A1 (en) * 2011-07-12 2013-01-17 The General Hospital Corporation Conjugating amines
RU2476444C1 (ru) * 2011-07-15 2013-02-27 Российская Федерация, от имени которой выступает Министерство промышленности и торговли Российской Федерации (Минпромторг России) СПОСОБ ПОЛУЧЕНИЯ КОНЪЮГАТА НОНА-β-(1→3)-ГЛЮКОЗИДА С БЫЧЬИМ СЫВОРОТОЧНЫМ АЛЬБУМИНОМ СКВАРАТНЫМ МЕТОДОМ
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
MY198910A (en) 2012-03-09 2023-10-02 Pfizer Neisseria meningitidis compositions and methods thereof
WO2014130613A2 (en) * 2013-02-22 2014-08-28 Amgen Inc. Carbohydrate phosphonate derivatives as modulators of glycosylation
WO2014136064A2 (en) 2013-03-08 2014-09-12 Pfizer Inc. Immunogenic fusion polypeptides
MX2016000099A (es) * 2013-07-07 2016-07-07 Max Planck Ges Zur Förderung Der Wissenschaften E V Vacunas sinteticas contra streptococcus pneumoniae tipo 1.
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
CN106061986B (zh) * 2014-02-25 2020-07-07 默沙东和惠康基金会合资的希勒曼实验室私人有限公司 脑膜炎奈瑟菌血清组x的新的合成寡聚体及其制备方法
EA201700177A1 (ru) * 2014-10-09 2017-07-31 Мсд Уэлком Траст Хиллеман Лабораторис Пвт. Лтд. Улучшенный способ конъюгирования и полученные с помощью него новые синтетические конъюгаты олигосахарида с белком
WO2016132294A1 (en) 2015-02-19 2016-08-25 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
BR112019003992A2 (pt) 2016-09-02 2019-05-28 Sanofi Pasteur Inc vacina contra neisseria meningitidis
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
WO2018173068A1 (en) * 2017-03-21 2018-09-27 Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd. A novel synthetic neisseria meningitidis serogroup a oligomer and process for synthesizing thereof
CA3120451A1 (en) 2018-11-22 2020-05-28 Idorsia Pharmaceuticals Ltd Stable vaccine against clostridium difficile with modifications to the ps-ii saccharide
WO2021059181A1 (en) 2019-09-27 2021-04-01 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CN118178643B (zh) * 2024-04-28 2024-11-29 亚培烯科技(上海)有限公司 饱和α烯烃低聚物作为佐剂在动物疫苗中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US6114309A (en) * 1997-11-21 2000-09-05 Incara Research Laboratories Combinatorial library of moenomycin analogs and methods of producing same
JP4774496B2 (ja) * 2001-06-14 2011-09-14 独立行政法人産業技術総合研究所 α−マンノシダーゼ
ES2616180T3 (es) * 2002-03-26 2017-06-09 Glaxosmithkline Biologicals Sa Sacáridos modificados con estabilidad mejorada en agua para su uso como medicamento
GB0220198D0 (en) 2002-08-30 2002-10-09 Chiron Spa Modified saccharides,conjugates thereof and their manufacture
EP2172213B1 (en) * 2003-01-30 2013-04-03 Novartis AG Injectable vaccines against multiple meningococcal serogroups
RU2250113C2 (ru) * 2003-06-04 2005-04-20 Институт биоорганической химии им. академиков М.М.Шемякина и Ю.А.Овчинникова Российской академии наук Способ приготовления бивалентной вакцины для профилактики менингококковой инфекции

Also Published As

Publication number Publication date
JP2008540398A (ja) 2008-11-20
AU2006245440A1 (en) 2006-11-16
US20090304734A1 (en) 2009-12-10
EP1885734B1 (en) 2015-01-14
WO2006120576A2 (en) 2006-11-16
ZA200710558B (en) 2010-04-28
EP1885734A2 (en) 2008-02-13
CA2606890C (en) 2014-02-04
MX2007013881A (es) 2008-10-22
PL1885734T3 (pl) 2015-08-31
US8062641B2 (en) 2011-11-22
PT1885734E (pt) 2015-03-04
CA2606890A1 (en) 2006-11-16
RU2007145219A (ru) 2009-06-20
AU2006245440B2 (en) 2012-04-19
CN101282984B (zh) 2013-05-08
CN101282984A (zh) 2008-10-08
ES2533248T3 (es) 2015-04-08
BRPI0611447A2 (pt) 2010-09-08
WO2006120576A3 (en) 2007-07-12
JP5699174B2 (ja) 2015-04-08
RU2412944C2 (ru) 2011-02-27
JP2013136639A (ja) 2013-07-11

Similar Documents

Publication Publication Date Title
CA2606890C (en) Immunogens for meningitidis-a vaccines
EP0276516B1 (en) New oligosaccharides, immunogens and vaccines, and methods for preparing such oligosaccharides, immunogens and vaccines
US20240024489A1 (en) Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
JP6526692B2 (ja) 髄膜炎菌（Ｎｅｉｓｓｅｒｉａ ｍｅｎｉｎｇｉｔｉｄｉｓ）血清型Ｘの新規の合成オリゴマー及びその調製方法
KR100818163B1 (ko) 리보즈-리비톨-인산염의 올리고당 유도체 및 이를포함하는 백신
US20230346905A1 (en) Pentavalent vaccine against neisseria meningitidis comprising a synthetic men a antigen
Auberger Synthesis of Neisseria meningitidis serogroup A carba analogues as hydrolytically stable antigens for antimeningococcal glycoconjugate vaccines
WO2018173068A1 (en) A novel synthetic neisseria meningitidis serogroup a oligomer and process for synthesizing thereof

Legal Events

Date Code Title Description
S881 Correction of error according section 88(1) (mistake in register by reason of an error or omission on the part of the patent office)

Free format text: THE APPLICANTS (71) AND INVENTORS (72) HAVE BEEN CORRECTED

PSEA Patent sealed
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 08 MAY 2016 BY CPA GLOBAL

Effective date: 20130405

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 08 MAY 2017 BY THOMSON REUTERS

Effective date: 20160415

LAPS Patent lapsed