NZ552335A - Combinations comprising a selective COX-2 inhibitor and a microtubule interfering agent - Google Patents
Combinations comprising a selective COX-2 inhibitor and a microtubule interfering agentInfo
- Publication number
- NZ552335A NZ552335A NZ552335A NZ55233502A NZ552335A NZ 552335 A NZ552335 A NZ 552335A NZ 552335 A NZ552335 A NZ 552335A NZ 55233502 A NZ55233502 A NZ 55233502A NZ 552335 A NZ552335 A NZ 552335A
- Authority
- NZ
- New Zealand
- Prior art keywords
- fluoro
- methyl
- chloro
- inhibitor
- hydrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34473501P | 2001-10-25 | 2001-10-25 | |
US34473401P | 2001-10-25 | 2001-10-25 | |
US33603301P | 2001-11-15 | 2001-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ552335A true NZ552335A (en) | 2008-11-28 |
Family
ID=27407094
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ532418A NZ532418A (en) | 2001-10-25 | 2002-10-24 | Combinations comprising a selective cyclooxygenase-2 inhibitor and a microtubule interfering agent |
NZ552335A NZ552335A (en) | 2001-10-25 | 2002-10-24 | Combinations comprising a selective COX-2 inhibitor and a microtubule interfering agent |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ532418A NZ532418A (en) | 2001-10-25 | 2002-10-24 | Combinations comprising a selective cyclooxygenase-2 inhibitor and a microtubule interfering agent |
Country Status (23)
Country | Link |
---|---|
US (2) | US20050043409A1 (es) |
EP (1) | EP1441714B1 (es) |
JP (1) | JP2005506366A (es) |
KR (1) | KR100954625B1 (es) |
CN (1) | CN100506224C (es) |
AT (1) | ATE381930T1 (es) |
AU (2) | AU2006252156A1 (es) |
BR (1) | BR0213486A (es) |
CA (1) | CA2464309C (es) |
CY (1) | CY1108045T1 (es) |
DE (1) | DE60224299T2 (es) |
DK (1) | DK1441714T3 (es) |
ES (1) | ES2295428T3 (es) |
HK (1) | HK1068261A1 (es) |
HU (1) | HUP0600235A3 (es) |
IL (1) | IL161462A0 (es) |
MX (1) | MXPA04003878A (es) |
NZ (2) | NZ532418A (es) |
PL (1) | PL369305A1 (es) |
PT (1) | PT1441714E (es) |
RU (1) | RU2333754C2 (es) |
SI (1) | SI1441714T1 (es) |
WO (1) | WO2003035047A2 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0223341D0 (en) * | 2002-10-08 | 2002-11-13 | Groningen Acad Ziekenhuis | Organic compounds |
BRPI0413876A (pt) | 2003-08-29 | 2006-10-24 | Pfizer | tienopiridin-fenilacetamidas e seus derivados úteis como agentes antiangiogênicos |
WO2005027972A2 (en) * | 2003-09-23 | 2005-03-31 | Novartis Ag | Combination of a vegf receptor inhibitor with a chemotherapeutic agent |
JP2007505939A (ja) * | 2003-09-23 | 2007-03-15 | ノバルティス アクチエンゲゼルシャフト | Vegf受容体阻害剤と他の治療剤の組み合わせ |
BRPI0418102A (pt) | 2003-12-23 | 2007-04-27 | Pfizer | derivados de quinolina |
JO2596B1 (en) * | 2004-11-30 | 2011-02-27 | نوفارتيس ايه جي | Compositions include epothelones and tyrosine protein kinase inhibitors and their pharmaceutical uses |
JP5133071B2 (ja) | 2006-02-09 | 2013-01-30 | 第一三共株式会社 | 抗癌医薬組成物 |
EP2065054A1 (en) | 2007-11-29 | 2009-06-03 | Bayer Schering Pharma Aktiengesellschaft | Combinations comprising a prostaglandin and uses thereof |
JO3002B1 (ar) | 2009-08-28 | 2016-09-05 | Irm Llc | مركبات و تركيبات كمثبطات كيناز بروتين |
CN108542906A (zh) | 2011-11-11 | 2018-09-18 | 诺华股份有限公司 | 治疗增生性疾病的方法 |
MD565Z (ro) * | 2012-05-23 | 2013-07-31 | Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы | Procedeu de tratare a seminţelor de sfeclă de zahăr |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1479385E (pt) * | 1996-10-15 | 2008-09-02 | Searle Llc | Utilização de inibidores de ciclo-oxigenase 2 no tratamento e na prevenção de neoplasias |
US6380394B1 (en) * | 1996-12-13 | 2002-04-30 | The Scripps Research Institute | Epothilone analogs |
CO4950519A1 (es) * | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
US6034256A (en) * | 1997-04-21 | 2000-03-07 | G.D. Searle & Co. | Substituted benzopyran derivatives for the treatment of inflammation |
CO4960662A1 (es) * | 1997-08-28 | 2000-09-25 | Novartis Ag | Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados |
US6025353A (en) * | 1997-11-19 | 2000-02-15 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents |
NZ333399A (en) * | 1997-12-24 | 2000-05-26 | Sankyo Co | Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis |
IL143901A0 (en) * | 1998-12-23 | 2002-04-21 | Searle & Co | Use of cyclooxygenase-2- inhibitor, a matrix metallaproteinase inhibitor, an antineoplastic agent and optionally radiation as a combination treatment of neoplasia |
KR20020018201A (ko) * | 1999-08-12 | 2002-03-07 | 윌리암 에이취 캘넌, 에곤 이 버그 | 결장 폴립 및 결장직장암의 치료 또는 억제용엔에스에이아이디 및 이지에프알 키나제 억제제 함유 조성물 |
JP2003517475A (ja) * | 1999-12-03 | 2003-05-27 | ファイザー・プロダクツ・インク | 抗炎症/鎮痛薬としてのヘテロシクロ−アルキルスルホニルピラゾール誘導体 |
ITMI992711A1 (it) * | 1999-12-27 | 2001-06-27 | Novartis Ag | Composti organici |
EP1259237A4 (en) * | 2000-02-17 | 2004-07-28 | Merck & Co Inc | TREATMENT OR PREVENTION OF PROSTATE CANCER USING A SELECTIVE COX-2 INHIBITOR MEDICINE |
WO2001062252A1 (en) * | 2000-02-25 | 2001-08-30 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
AU2001232175B2 (en) * | 2000-03-03 | 2005-07-07 | Pfizer Products Inc. | Pyrazole ether derivatives as anti-inflammatory/analgesic agents |
TWI310684B (en) * | 2000-03-27 | 2009-06-11 | Bristol Myers Squibb Co | Synergistic pharmaceutical kits for treating cancer |
-
2002
- 2002-10-24 CN CNB028211375A patent/CN100506224C/zh not_active Expired - Fee Related
- 2002-10-24 MX MXPA04003878A patent/MXPA04003878A/es active IP Right Grant
- 2002-10-24 EP EP02787507A patent/EP1441714B1/en not_active Expired - Lifetime
- 2002-10-24 NZ NZ532418A patent/NZ532418A/en not_active IP Right Cessation
- 2002-10-24 BR BR0213486-1A patent/BR0213486A/pt active Search and Examination
- 2002-10-24 AT AT02787507T patent/ATE381930T1/de active
- 2002-10-24 US US10/493,297 patent/US20050043409A1/en not_active Abandoned
- 2002-10-24 IL IL16146202A patent/IL161462A0/xx unknown
- 2002-10-24 RU RU2004116069/15A patent/RU2333754C2/ru not_active IP Right Cessation
- 2002-10-24 PT PT02787507T patent/PT1441714E/pt unknown
- 2002-10-24 CA CA2464309A patent/CA2464309C/en not_active Expired - Fee Related
- 2002-10-24 PL PL02369305A patent/PL369305A1/xx not_active Application Discontinuation
- 2002-10-24 WO PCT/EP2002/011924 patent/WO2003035047A2/en active IP Right Grant
- 2002-10-24 SI SI200230672T patent/SI1441714T1/sl unknown
- 2002-10-24 NZ NZ552335A patent/NZ552335A/en not_active IP Right Cessation
- 2002-10-24 JP JP2003537614A patent/JP2005506366A/ja active Pending
- 2002-10-24 DK DK02787507T patent/DK1441714T3/da active
- 2002-10-24 HU HU0600235A patent/HUP0600235A3/hu unknown
- 2002-10-24 ES ES02787507T patent/ES2295428T3/es not_active Expired - Lifetime
- 2002-10-24 KR KR1020047006101A patent/KR100954625B1/ko not_active IP Right Cessation
- 2002-10-24 DE DE60224299T patent/DE60224299T2/de not_active Expired - Lifetime
-
2005
- 2005-01-14 HK HK05100398A patent/HK1068261A1/xx not_active IP Right Cessation
-
2006
- 2006-12-20 AU AU2006252156A patent/AU2006252156A1/en not_active Abandoned
-
2008
- 2008-02-18 CY CY20081100197T patent/CY1108045T1/el unknown
-
2010
- 2010-02-08 AU AU2010200433A patent/AU2010200433A1/en not_active Abandoned
- 2010-11-03 US US12/938,868 patent/US20110046190A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NZ532418A (en) | 2007-02-23 |
PT1441714E (pt) | 2008-03-10 |
KR20040048992A (ko) | 2004-06-10 |
DK1441714T3 (da) | 2008-03-31 |
HUP0600235A2 (en) | 2007-02-28 |
SI1441714T1 (sl) | 2008-06-30 |
HUP0600235A3 (en) | 2008-04-28 |
AU2010200433A1 (en) | 2010-02-25 |
DE60224299D1 (de) | 2008-02-07 |
RU2333754C2 (ru) | 2008-09-20 |
EP1441714B1 (en) | 2007-12-26 |
ATE381930T1 (de) | 2008-01-15 |
PL369305A1 (en) | 2005-04-18 |
EP1441714A2 (en) | 2004-08-04 |
ES2295428T3 (es) | 2008-04-16 |
JP2005506366A (ja) | 2005-03-03 |
DE60224299T2 (de) | 2008-12-11 |
AU2006252156A1 (en) | 2007-01-18 |
BR0213486A (pt) | 2005-05-10 |
CN100506224C (zh) | 2009-07-01 |
WO2003035047A3 (en) | 2003-10-23 |
KR100954625B1 (ko) | 2010-04-27 |
MXPA04003878A (es) | 2004-07-08 |
CN1575168A (zh) | 2005-02-02 |
RU2004116069A (ru) | 2005-06-10 |
US20050043409A1 (en) | 2005-02-24 |
WO2003035047A2 (en) | 2003-05-01 |
CA2464309C (en) | 2012-01-03 |
HK1068261A1 (en) | 2005-04-29 |
US20110046190A1 (en) | 2011-02-24 |
CA2464309A1 (en) | 2003-05-01 |
CY1108045T1 (el) | 2013-09-04 |
IL161462A0 (en) | 2004-09-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20110046190A1 (en) | Combinations comprising a selective cyclooxygenase-2 inhibitor | |
JP6798890B2 (ja) | グルタミナーゼ阻害剤との併用療法 | |
US20060270665A1 (en) | Combination comprising an agent decreasing VEGF activity and an agent decreasing EGF activity | |
RU2660354C2 (ru) | Комбинированные продукты, содержащие ингибиторы тирозинкиназ, и их применение | |
CN106456635A (zh) | Mdm2抑制剂的间歇给药 | |
MX2008016125A (es) | Compuestos organicos. | |
US7723339B2 (en) | Combination comprising a signal transduction inhibitor and an epothilone derivative | |
RU2469721C2 (ru) | Комбинация, включающая комплексон железа и противоопухолевый агент, и ее применение | |
AU2002308218A1 (en) | Combination comprising a signal transduction inhibitor and an epothilone derivative | |
ZA200402939B (en) | Combinations comprising a selective cyclooxygenase-2 inhibitor. | |
AU2002351784A1 (en) | Combinations comprising a selective cyclooxygenase-2 inhibitor | |
MX2012015040A (es) | Agente terapeutico de liberacion sostenida para la hipertension y la disfuncion renal. | |
TW200950789A (en) | Antitumor agent, kit and method of treating cancer | |
TWI343258B (en) | Combination comprising an active ingredient which decreases the activity of the epidermal growth factor (egf) and an epothilone derivative | |
CN117377492A (zh) | 包含蛋白激酶抑制剂的药物组合物及其医药用途 | |
NZ615005A (en) | Combinations comprising macitentan for the treatment of glioblastoma multiforme | |
NZ615005B2 (en) | Combinations comprising macitentan for the treatment of glioblastoma multiforme |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RENW | Renewal (renewal fees accepted) | ||
RENW | Renewal (renewal fees accepted) | ||
RENW | Renewal (renewal fees accepted) | ||
LAPS | Patent lapsed |