ATE381930T1 - Kombinationsmedikationen mit einem selektiven cyclooxygenase-2-inhibitor - Google Patents

Kombinationsmedikationen mit einem selektiven cyclooxygenase-2-inhibitor

Info

Publication number
ATE381930T1
ATE381930T1 AT02787507T AT02787507T ATE381930T1 AT E381930 T1 ATE381930 T1 AT E381930T1 AT 02787507 T AT02787507 T AT 02787507T AT 02787507 T AT02787507 T AT 02787507T AT E381930 T1 ATE381930 T1 AT E381930T1
Authority
AT
Austria
Prior art keywords
inhibitor
growth factor
selective cyclooxygenase
factor receptor
receptor tyrosine
Prior art date
Application number
AT02787507T
Other languages
English (en)
Inventor
Ying-Nan Chen
Peter Lassota
Alexander Wood
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE381930T1 publication Critical patent/ATE381930T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02787507T 2001-10-25 2002-10-24 Kombinationsmedikationen mit einem selektiven cyclooxygenase-2-inhibitor ATE381930T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34473501P 2001-10-25 2001-10-25
US34473401P 2001-10-25 2001-10-25
US33603301P 2001-11-15 2001-11-15

Publications (1)

Publication Number Publication Date
ATE381930T1 true ATE381930T1 (de) 2008-01-15

Family

ID=27407094

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02787507T ATE381930T1 (de) 2001-10-25 2002-10-24 Kombinationsmedikationen mit einem selektiven cyclooxygenase-2-inhibitor

Country Status (23)

Country Link
US (2) US20050043409A1 (de)
EP (1) EP1441714B1 (de)
JP (1) JP2005506366A (de)
KR (1) KR100954625B1 (de)
CN (1) CN100506224C (de)
AT (1) ATE381930T1 (de)
AU (2) AU2006252156A1 (de)
BR (1) BR0213486A (de)
CA (1) CA2464309C (de)
CY (1) CY1108045T1 (de)
DE (1) DE60224299T2 (de)
DK (1) DK1441714T3 (de)
ES (1) ES2295428T3 (de)
HK (1) HK1068261A1 (de)
HU (1) HUP0600235A3 (de)
IL (1) IL161462A0 (de)
MX (1) MXPA04003878A (de)
NZ (2) NZ552335A (de)
PL (1) PL369305A1 (de)
PT (1) PT1441714E (de)
RU (1) RU2333754C2 (de)
SI (1) SI1441714T1 (de)
WO (1) WO2003035047A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0223341D0 (en) * 2002-10-08 2002-11-13 Groningen Acad Ziekenhuis Organic compounds
MXPA06002296A (es) 2003-08-29 2006-05-22 Pfizer Tienopiridina-fenilacetamidas y sus derivados utiles como nuevos agentes antiangiogenicos.
US20080085902A1 (en) * 2003-09-23 2008-04-10 Guido Bold Combination Of A Vegf Receptor Inhibitor Or With A Chemotherapeutic Agent
WO2005027973A2 (en) * 2003-09-23 2005-03-31 Novartis Ag Combinations of a vegf receptor inhibitor with other therapeutic agents
MXPA06007242A (es) 2003-12-23 2006-08-18 Pfizer Nuevos derivados de quinolina.
JO2596B1 (en) * 2004-11-30 2011-02-27 نوفارتيس ايه جي Compositions include epothelones and tyrosine protein kinase inhibitors and their pharmaceutical uses
TW200800181A (en) * 2006-02-09 2008-01-01 Sankyo Co Pharmaceutical composition for anticancer
EP2065054A1 (de) 2007-11-29 2009-06-03 Bayer Schering Pharma Aktiengesellschaft Kombinationen mit einem Prostaglandin und Verwendungen davon
JO3002B1 (ar) 2009-08-28 2016-09-05 Irm Llc مركبات و تركيبات كمثبطات كيناز بروتين
CN108542906A (zh) 2011-11-11 2018-09-18 诺华股份有限公司 治疗增生性疾病的方法
MD565Z (ro) * 2012-05-23 2013-07-31 Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы Procedeu de tratare a seminţelor de sfeclă de zahăr

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0932402T3 (da) * 1996-10-15 2004-11-08 Searle Llc Metode til anvendelse af cyclooxygenase-2-inhibitorer ved behandling og forebyggelse af neoplasi
US6380394B1 (en) * 1996-12-13 2002-04-30 The Scripps Research Institute Epothilone analogs
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
US6034256A (en) * 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
CO4960662A1 (es) * 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
US6025353A (en) * 1997-11-19 2000-02-15 G.D. Searle & Co. Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents
NZ333399A (en) * 1997-12-24 2000-05-26 Sankyo Co Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis
CZ20012320A3 (cs) * 1998-12-23 2002-10-16 G. D. Searle & Co. Léčivo s obsahem inhibitoru cyklooxygenázy-2 a jednoho nebo více antineoplastických činidel pro kombinační terapii při léčení neoplasie
NZ517120A (en) * 1999-08-12 2004-10-29 Wyeth Corp NSAID and EFGR kinase inhibitor containing composition for the treatment or inhibition of colonic polyps and colorectal cancer
BR0016031A (pt) * 1999-12-03 2002-07-23 Pfizer Prod Inc Derivados de heterociclo-alquilsulfonil pirazol como agentes antiinflamatórios/analgésicos
ITMI992711A1 (it) * 1999-12-27 2001-06-27 Novartis Ag Composti organici
JP2003522790A (ja) * 2000-02-17 2003-07-29 メルク エンド カムパニー インコーポレーテッド Ｃｏｘ−２選択的阻害薬を用いた前立腺癌の治療または予防
EP1259236A4 (de) * 2000-02-25 2004-11-03 Merck & Co Inc Tyrosinkinase-inhibitoren
AU3217501A (en) * 2000-03-03 2001-09-12 Pfizer Prod Inc Pyrazole ether derivatives as anti-inflammatory/analgesic agents
TWI310684B (en) * 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer

Also Published As

Publication number Publication date
RU2333754C2 (ru) 2008-09-20
CA2464309C (en) 2012-01-03
IL161462A0 (en) 2004-09-27
CY1108045T1 (el) 2013-09-04
WO2003035047A3 (en) 2003-10-23
HUP0600235A2 (en) 2007-02-28
MXPA04003878A (es) 2004-07-08
KR100954625B1 (ko) 2010-04-27
US20110046190A1 (en) 2011-02-24
HUP0600235A3 (en) 2008-04-28
RU2004116069A (ru) 2005-06-10
BR0213486A (pt) 2005-05-10
NZ532418A (en) 2007-02-23
DK1441714T3 (da) 2008-03-31
WO2003035047A2 (en) 2003-05-01
ES2295428T3 (es) 2008-04-16
SI1441714T1 (sl) 2008-06-30
CN1575168A (zh) 2005-02-02
US20050043409A1 (en) 2005-02-24
JP2005506366A (ja) 2005-03-03
AU2006252156A1 (en) 2007-01-18
EP1441714A2 (de) 2004-08-04
NZ552335A (en) 2008-11-28
CN100506224C (zh) 2009-07-01
KR20040048992A (ko) 2004-06-10
EP1441714B1 (de) 2007-12-26
PL369305A1 (en) 2005-04-18
DE60224299T2 (de) 2008-12-11
AU2010200433A1 (en) 2010-02-25
PT1441714E (pt) 2008-03-10
HK1068261A1 (en) 2005-04-29
CA2464309A1 (en) 2003-05-01
DE60224299D1 (de) 2008-02-07

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