NZ539675A - Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer - Google Patents

Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer

Info

Publication number
NZ539675A
NZ539675A NZ539675A NZ53967503A NZ539675A NZ 539675 A NZ539675 A NZ 539675A NZ 539675 A NZ539675 A NZ 539675A NZ 53967503 A NZ53967503 A NZ 53967503A NZ 539675 A NZ539675 A NZ 539675A
Authority
NZ
New Zealand
Prior art keywords
alkyl
compound
cancer
tumor
cell
Prior art date
Application number
NZ539675A
Other languages
English (en)
Inventor
Glenn Friedman
Jeffrey Mickie
Jonathan Wright
Original Assignee
Signal Pharm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signal Pharm Llc filed Critical Signal Pharm Llc
Publication of NZ539675A publication Critical patent/NZ539675A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
NZ539675A 2002-10-15 2003-10-15 Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer NZ539675A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41846902P 2002-10-15 2002-10-15
US10/685,722 US7091235B2 (en) 2002-10-15 2003-10-14 Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer
PCT/US2003/032932 WO2004035002A2 (en) 2002-10-15 2003-10-15 Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer

Publications (1)

Publication Number Publication Date
NZ539675A true NZ539675A (en) 2006-10-27

Family

ID=32110155

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ539675A NZ539675A (en) 2002-10-15 2003-10-15 Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer

Country Status (13)

Country Link
US (3) US7091235B2 (enExample)
EP (1) EP1556374A4 (enExample)
JP (1) JP2006515275A (enExample)
KR (1) KR20050072764A (enExample)
CN (1) CN100457751C (enExample)
AU (1) AU2003286441A1 (enExample)
BR (1) BR0315400A (enExample)
CA (1) CA2502064A1 (enExample)
IL (1) IL168059A0 (enExample)
MX (1) MXPA05003909A (enExample)
NZ (1) NZ539675A (enExample)
WO (1) WO2004035002A2 (enExample)
ZA (1) ZA200503026B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091235B2 (en) * 2002-10-15 2006-08-15 Signal Pharmaceuticals, Llc Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer
EP1654225A4 (en) * 2003-08-13 2007-11-28 Amgen Inc HORMONE RECEPTOR ANTAGONISTS CONCENTRATING MELANIN
WO2005019167A2 (en) * 2003-08-13 2005-03-03 Amgen, Inc. Melanin concentrating hormone receptor antagonist
WO2005028472A1 (en) * 2003-09-15 2005-03-31 Signal Pharmaceuticals, Llc Benzopyranone compounds, compositions thereof, and methods of treatment therewith
WO2006078833A2 (en) * 2005-01-21 2006-07-27 Janssen Pharmaceutica N.V. Novel coumarin derivatives as ion channel openers
AU2006262190A1 (en) * 2005-06-24 2007-01-04 Signal Pharmaceuticals, Llc. Benzopyranone compounds for treating cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US633155A (en) 1898-02-23 1899-09-19 William W Ramsay Fence-repairing tool.
US5633155A (en) * 1992-08-19 1997-05-27 Jinro Limited Expression vector for phytolacca antiviral protein and process for preparing transgenic plant transformed therewith
US6444688B1 (en) * 1995-06-07 2002-09-03 Eli Lilly And Company Compounds and compositions with nitrogen-containing non-basic side chains
US6331562B1 (en) * 1998-12-30 2001-12-18 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
US6291456B1 (en) * 1998-12-30 2001-09-18 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
IL144003A0 (en) * 1998-12-30 2002-04-21 Signal Pharm Inc Compounds and methods for modulation of estrogen receptors
KR20020075388A (ko) 1999-12-30 2002-10-04 시그널 파머슈티컬스 인크 에스트로겐 수용체의 조절 화합물 및 조절 방법
US7148252B2 (en) * 2001-10-03 2006-12-12 Signal Pharmaceuticals, Llc Use of benzopyranones for treating or preventing a primary brain cancer or a brain metastasis
US6620838B1 (en) * 2002-04-19 2003-09-16 Signal Pharmaceuticals, Inc. Benzopyrazone compounds, compositions thereof, and methods of treatment therewith
WO2003089422A1 (en) * 2002-04-19 2003-10-30 Signal Pharmaceuticals, Inc. Benzopyranone compounds, compositions thereof, and methods of treatment therewith
US7091235B2 (en) * 2002-10-15 2006-08-15 Signal Pharmaceuticals, Llc Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer

Also Published As

Publication number Publication date
US7091235B2 (en) 2006-08-15
WO2004035002A2 (en) 2004-04-29
US20080146648A1 (en) 2008-06-19
CN1717405A (zh) 2006-01-04
CN100457751C (zh) 2009-02-04
WO2004035002A3 (en) 2004-08-26
EP1556374A2 (en) 2005-07-27
EP1556374A4 (en) 2007-12-19
KR20050072764A (ko) 2005-07-12
US20060194866A1 (en) 2006-08-31
ZA200503026B (en) 2006-11-29
JP2006515275A (ja) 2006-05-25
BR0315400A (pt) 2005-08-16
IL168059A0 (en) 2009-02-11
MXPA05003909A (es) 2005-09-30
US7358274B2 (en) 2008-04-15
US7589119B2 (en) 2009-09-15
AU2003286441A1 (en) 2004-05-04
US20040225005A1 (en) 2004-11-11
CA2502064A1 (en) 2004-04-29

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
ERR Error or correction

Free format text: THE OWNER HAS BEEN CORRECTED TO 3148433, SIGNAL PHARMACEUTICALS, LLC, 10300 CAMPUS POINT DRIVE, SUITE 100SAN DIEGO, CA 92121, US

Effective date: 20150806