NZ533750A - N-Pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases - Google Patents
N-Pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseasesInfo
- Publication number
- NZ533750A NZ533750A NZ533750A NZ53375003A NZ533750A NZ 533750 A NZ533750 A NZ 533750A NZ 533750 A NZ533750 A NZ 533750A NZ 53375003 A NZ53375003 A NZ 53375003A NZ 533750 A NZ533750 A NZ 533750A
- Authority
- NZ
- New Zealand
- Prior art keywords
- alkyl
- treatment
- mediated diseases
- phenylsulphonamides
- pyrazinyl
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000001404 mediated effect Effects 0.000 title abstract 2
- 102000019034 Chemokines Human genes 0.000 title 1
- 108010012236 Chemokines Proteins 0.000 title 1
- KAPFAVLCJMCLFV-UHFFFAOYSA-N n-pyrazin-2-ylbenzenesulfonamide Chemical class C=1C=CC=CC=1S(=O)(=O)NC1=CN=CC=N1 KAPFAVLCJMCLFV-UHFFFAOYSA-N 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- -1 CO2R12 Chemical group 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
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- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
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- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
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- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
- C07D241/22—Benzenesulfonamido pyrazines
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- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
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- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- AIDS & HIV (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0200119A SE0200119D0 (sv) | 2002-01-16 | 2002-01-16 | Novel compounds |
| SE0201857A SE0201857D0 (sv) | 2002-06-17 | 2002-06-17 | Novel compounds |
| PCT/SE2003/000041 WO2003059893A1 (en) | 2002-01-16 | 2003-01-14 | N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ533750A true NZ533750A (en) | 2006-03-31 |
Family
ID=26655657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ533750A NZ533750A (en) | 2002-01-16 | 2003-01-14 | N-Pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7662825B2 (enExample) |
| EP (1) | EP1467976B1 (enExample) |
| JP (1) | JP4504021B2 (enExample) |
| KR (1) | KR20040073566A (enExample) |
| CN (1) | CN100357275C (enExample) |
| AR (1) | AR038179A1 (enExample) |
| AT (1) | ATE534635T1 (enExample) |
| AU (1) | AU2003201802A1 (enExample) |
| BR (1) | BR0306922A (enExample) |
| CA (1) | CA2472204A1 (enExample) |
| CO (1) | CO5640137A2 (enExample) |
| ES (1) | ES2375107T3 (enExample) |
| IL (1) | IL162678A0 (enExample) |
| IS (1) | IS7348A (enExample) |
| MX (1) | MXPA04006806A (enExample) |
| NO (1) | NO20043370L (enExample) |
| NZ (1) | NZ533750A (enExample) |
| PL (1) | PL371432A1 (enExample) |
| RU (1) | RU2312105C9 (enExample) |
| TW (1) | TWI328007B (enExample) |
| WO (1) | WO2003059893A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004007472A1 (ja) * | 2002-07-10 | 2004-01-22 | Ono Pharmaceutical Co., Ltd. | Ccr4アンタゴニストおよびその医薬用途 |
| GB0217431D0 (en) | 2002-07-27 | 2002-09-04 | Astrazeneca Ab | Novel compounds |
| AU2003255819A1 (en) | 2002-08-24 | 2004-03-11 | Astrazeneca Ab | Pyrimidine derivatives as modulators of chemokine receptor activity |
| SE0301653D0 (sv) * | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
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| GB0526255D0 (en) | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| UA98961C2 (uk) | 2007-06-27 | 2012-07-10 | Астразенека Аб | Похідні піразинону та їх застосування у лікуванні легеневих захворювань |
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| WO2012082633A1 (en) * | 2010-12-16 | 2012-06-21 | Allergan, Inc. | Novel 1,2- bis-sulfonamide derivatives as chemokine receptor modulators |
| ES2903205T3 (es) | 2011-11-09 | 2022-03-31 | Kyowa Kirin Co Ltd | Compuestos heterocíclicos que contienen nitrógeno |
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| US143024A (en) * | 1873-09-23 | Improvement in clothes-pins | ||
| US5962490A (en) | 1987-09-25 | 1999-10-05 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
| GB9504854D0 (en) * | 1994-03-31 | 1995-04-26 | Zeneca Ltd | Nitrogen derivatives |
| CA2162630C (en) | 1994-11-25 | 2007-05-01 | Volker Breu | Sulfonamides |
| GB2295616A (en) * | 1994-12-01 | 1996-06-05 | Zeneca Ltd | N-Diazine-benzenesulphonamide derivatives as endothelin receptor antagonists |
| GB9512697D0 (en) | 1995-06-22 | 1995-08-23 | Zeneca Ltd | Heterocyclic compounds |
| ID26984A (id) * | 1998-07-06 | 2001-02-22 | Bristol Myers Squibb Co | Senyawa-senyawa sulfonamida sebagai antagonis reseptor angiotensin endotelin ganda |
| US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| WO2001044239A2 (en) * | 1999-12-15 | 2001-06-21 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| AU2002358390A1 (en) | 2001-12-18 | 2003-06-30 | Astrazeneca Ab | Novel compounds |
| WO2004007472A1 (ja) | 2002-07-10 | 2004-01-22 | Ono Pharmaceutical Co., Ltd. | Ccr4アンタゴニストおよびその医薬用途 |
| SE0301650D0 (sv) | 2003-06-04 | 2003-06-04 | Astrazeneca Ab | Novel compounds |
| SE0301653D0 (sv) | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
| SE0301654D0 (sv) | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
| SE0302304D0 (sv) | 2003-08-27 | 2003-08-27 | Astrazeneca Ab | Novel compounds |
| TW200800921A (en) | 2005-09-19 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
| TW200730512A (en) | 2005-12-12 | 2007-08-16 | Astrazeneca Ab | Novel compounds |
-
2003
- 2003-01-07 TW TW092100237A patent/TWI328007B/zh active
- 2003-01-14 WO PCT/SE2003/000041 patent/WO2003059893A1/en not_active Ceased
- 2003-01-14 EP EP03700655A patent/EP1467976B1/en not_active Expired - Lifetime
- 2003-01-14 CN CNB038044811A patent/CN100357275C/zh not_active Expired - Fee Related
- 2003-01-14 ES ES03700655T patent/ES2375107T3/es not_active Expired - Lifetime
- 2003-01-14 AT AT03700655T patent/ATE534635T1/de active
- 2003-01-14 AU AU2003201802A patent/AU2003201802A1/en not_active Abandoned
- 2003-01-14 PL PL03371432A patent/PL371432A1/xx not_active Application Discontinuation
- 2003-01-14 BR BR0306922-2A patent/BR0306922A/pt not_active IP Right Cessation
- 2003-01-14 RU RU2004119966/04A patent/RU2312105C9/ru not_active IP Right Cessation
- 2003-01-14 MX MXPA04006806A patent/MXPA04006806A/es active IP Right Grant
- 2003-01-14 US US10/501,510 patent/US7662825B2/en not_active Expired - Fee Related
- 2003-01-14 KR KR10-2004-7010982A patent/KR20040073566A/ko not_active Ceased
- 2003-01-14 NZ NZ533750A patent/NZ533750A/xx unknown
- 2003-01-14 CA CA002472204A patent/CA2472204A1/en not_active Abandoned
- 2003-01-14 IL IL16267803A patent/IL162678A0/xx unknown
- 2003-01-14 JP JP2003559997A patent/JP4504021B2/ja not_active Expired - Fee Related
- 2003-01-16 AR ARP030100126A patent/AR038179A1/es unknown
-
2004
- 2004-07-08 IS IS7348A patent/IS7348A/is unknown
- 2004-07-15 CO CO04067437A patent/CO5640137A2/es not_active Application Discontinuation
- 2004-08-13 NO NO20043370A patent/NO20043370L/no not_active Application Discontinuation
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- 2009-05-05 US US12/435,864 patent/US20100081670A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CO5640137A2 (es) | 2006-05-31 |
| RU2312105C2 (ru) | 2007-12-10 |
| TWI328007B (en) | 2010-08-01 |
| BR0306922A (pt) | 2004-11-09 |
| ATE534635T1 (de) | 2011-12-15 |
| RU2004119966A (ru) | 2005-06-10 |
| IL162678A0 (en) | 2005-11-20 |
| TW200303308A (en) | 2003-09-01 |
| JP4504021B2 (ja) | 2010-07-14 |
| WO2003059893A1 (en) | 2003-07-24 |
| CA2472204A1 (en) | 2003-07-24 |
| US20100081670A1 (en) | 2010-04-01 |
| KR20040073566A (ko) | 2004-08-19 |
| ES2375107T3 (es) | 2012-02-24 |
| IS7348A (is) | 2004-07-08 |
| JP2005521650A (ja) | 2005-07-21 |
| US20060025423A1 (en) | 2006-02-02 |
| MXPA04006806A (es) | 2004-12-06 |
| US7662825B2 (en) | 2010-02-16 |
| EP1467976B1 (en) | 2011-11-23 |
| PL371432A1 (en) | 2005-06-13 |
| CN100357275C (zh) | 2007-12-26 |
| EP1467976A1 (en) | 2004-10-20 |
| CN1639132A (zh) | 2005-07-13 |
| HK1068885A1 (en) | 2005-05-06 |
| RU2312105C9 (ru) | 2008-06-10 |
| AU2003201802A1 (en) | 2003-07-30 |
| NO20043370L (no) | 2004-09-28 |
| AR038179A1 (es) | 2005-01-05 |
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