NO20043370L - N-pyrazinylfenylsulfonamider og deres anvendelse ved behandling av kemokinmedierte sykdommer - Google Patents
N-pyrazinylfenylsulfonamider og deres anvendelse ved behandling av kemokinmedierte sykdommerInfo
- Publication number
- NO20043370L NO20043370L NO20043370A NO20043370A NO20043370L NO 20043370 L NO20043370 L NO 20043370L NO 20043370 A NO20043370 A NO 20043370A NO 20043370 A NO20043370 A NO 20043370A NO 20043370 L NO20043370 L NO 20043370L
- Authority
- NO
- Norway
- Prior art keywords
- pyrazinylphenylsulfonamides
- chemokine
- treatment
- mediated diseases
- mediated
- Prior art date
Links
- 102000019034 Chemokines Human genes 0.000 title 1
- 108010012236 Chemokines Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- KAPFAVLCJMCLFV-UHFFFAOYSA-N n-pyrazin-2-ylbenzenesulfonamide Chemical class C=1C=CC=CC=1S(=O)(=O)NC1=CN=CC=N1 KAPFAVLCJMCLFV-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
- C07D241/22—Benzenesulfonamido pyrazines
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- C—CHEMISTRY; METALLURGY
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- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
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- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
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- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Otolaryngology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0200119A SE0200119D0 (sv) | 2002-01-16 | 2002-01-16 | Novel compounds |
SE0201857A SE0201857D0 (sv) | 2002-06-17 | 2002-06-17 | Novel compounds |
PCT/SE2003/000041 WO2003059893A1 (en) | 2002-01-16 | 2003-01-14 | N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20043370L true NO20043370L (no) | 2004-09-28 |
Family
ID=26655657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20043370A NO20043370L (no) | 2002-01-16 | 2004-08-13 | N-pyrazinylfenylsulfonamider og deres anvendelse ved behandling av kemokinmedierte sykdommer |
Country Status (22)
Country | Link |
---|---|
US (2) | US7662825B2 (no) |
EP (1) | EP1467976B1 (no) |
JP (1) | JP4504021B2 (no) |
KR (1) | KR20040073566A (no) |
CN (1) | CN100357275C (no) |
AR (1) | AR038179A1 (no) |
AT (1) | ATE534635T1 (no) |
AU (1) | AU2003201802A1 (no) |
BR (1) | BR0306922A (no) |
CA (1) | CA2472204A1 (no) |
CO (1) | CO5640137A2 (no) |
ES (1) | ES2375107T3 (no) |
HK (1) | HK1068885A1 (no) |
IL (1) | IL162678A0 (no) |
IS (1) | IS7348A (no) |
MX (1) | MXPA04006806A (no) |
NO (1) | NO20043370L (no) |
NZ (1) | NZ533750A (no) |
PL (1) | PL371432A1 (no) |
RU (1) | RU2312105C9 (no) |
TW (1) | TWI328007B (no) |
WO (1) | WO2003059893A1 (no) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2004007472A1 (ja) * | 2002-07-10 | 2005-11-17 | 小野薬品工業株式会社 | Ccr4アンタゴニストおよびその医薬用途 |
GB0217431D0 (en) | 2002-07-27 | 2002-09-04 | Astrazeneca Ab | Novel compounds |
DE60318219T2 (de) | 2002-08-24 | 2009-01-15 | Astrazeneca Ab | PYRIMIDINDERIVATE ALS MODULATOREN DER AKTIVITuT VON CHEMOKINREZEPTOREN |
SE0301653D0 (sv) * | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
SE0302304D0 (sv) * | 2003-08-27 | 2003-08-27 | Astrazeneca Ab | Novel compounds |
EP1661889A4 (en) * | 2003-09-05 | 2009-08-05 | Ono Pharmaceutical Co | ANTAGONIST OF THE CHEMOKINE RECEPTOR AND ITS USE FOR MEDICAL PURPOSES |
GB0401269D0 (en) * | 2004-01-21 | 2004-02-25 | Astrazeneca Ab | Compounds |
CA2576993C (en) | 2004-08-12 | 2013-09-24 | Amgen Inc. | Bisaryl-sulfonamides |
SI1809624T1 (sl) | 2004-08-28 | 2014-02-28 | Astrazeneca Ab | Derivati pirimidinsulfonamida kot modulatorji receptorja kemokina |
TW200800921A (en) * | 2005-09-19 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
WO2007063934A1 (ja) * | 2005-12-02 | 2007-06-07 | Mitsubishi Tanabe Pharma Corporation | 脂環式複素環化合物 |
WO2007063935A1 (ja) * | 2005-12-02 | 2007-06-07 | Mitsubishi Tanabe Pharma Corporation | 芳香族化合物 |
TW200730512A (en) * | 2005-12-12 | 2007-08-16 | Astrazeneca Ab | Novel compounds |
GB0526255D0 (en) | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
AU2008269516B2 (en) | 2007-06-27 | 2011-11-17 | Astrazeneca Ab | Pyrazinone derivatives and their use in the treatment of lung diseases |
US8586748B2 (en) * | 2008-04-09 | 2013-11-19 | Boehringer Ingelheim International Gmbh | 2-sulfonylamino-4-heteroaryl butyramide antagonists of CCR10 |
US8673908B2 (en) | 2008-11-10 | 2014-03-18 | Kyowa Hakko Kirin Co., Ltd. | Kynurenine production inhibitor |
UA108073C2 (ru) * | 2009-04-22 | 2015-03-25 | Аксікін Фармасьютікалз, Інк. | 2,5-дизамещенные арилсульфонамидные антагонисты ccr3 |
TWI535442B (zh) | 2010-05-10 | 2016-06-01 | Kyowa Hakko Kirin Co Ltd | A nitrogen-containing heterocyclic compound having an action of inhibiting the production of canine erythritine |
EP2651901B1 (en) * | 2010-12-16 | 2015-05-27 | Allergan, Inc. | Novel 1,2- bis-sulfonamide derivatives as chemokine receptor modulators |
EP3312173B1 (en) | 2011-11-09 | 2021-12-22 | Kyowa Kirin Co., Ltd. | Nitrogen-containing heterocyclic compounds |
JP6327803B2 (ja) * | 2013-07-09 | 2018-05-23 | 久慶 ▲ふく▼楊 | 大出力高効率単相多極発電機 |
CN106008418A (zh) * | 2016-05-20 | 2016-10-12 | 厦门大学 | 一种5-氨甲基-2-呋喃甲醇的合成方法 |
CN113069446B (zh) * | 2021-03-01 | 2022-12-02 | 中山亿维迪科技有限公司 | El102在制备治疗新型冠状病毒所致疾病的药物中的应用 |
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US143024A (en) * | 1873-09-23 | Improvement in clothes-pins | ||
US5962490A (en) | 1987-09-25 | 1999-10-05 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
GB9504854D0 (en) * | 1994-03-31 | 1995-04-26 | Zeneca Ltd | Nitrogen derivatives |
CA2162630C (en) | 1994-11-25 | 2007-05-01 | Volker Breu | Sulfonamides |
GB2295616A (en) * | 1994-12-01 | 1996-06-05 | Zeneca Ltd | N-Diazine-benzenesulphonamide derivatives as endothelin receptor antagonists |
GB9512697D0 (en) | 1995-06-22 | 1995-08-23 | Zeneca Ltd | Heterocyclic compounds |
CA2336714A1 (en) * | 1998-07-06 | 2000-01-13 | Bristol-Myers Squibb Company | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
EP1237888B1 (en) * | 1999-12-15 | 2006-09-13 | Bristol-Myers Squibb Company | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
AU2002358390A1 (en) | 2001-12-18 | 2003-06-30 | Astrazeneca Ab | Novel compounds |
JPWO2004007472A1 (ja) | 2002-07-10 | 2005-11-17 | 小野薬品工業株式会社 | Ccr4アンタゴニストおよびその医薬用途 |
SE0301650D0 (sv) | 2003-06-04 | 2003-06-04 | Astrazeneca Ab | Novel compounds |
SE0301653D0 (sv) | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
SE0301654D0 (sv) | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
SE0302304D0 (sv) | 2003-08-27 | 2003-08-27 | Astrazeneca Ab | Novel compounds |
TW200800921A (en) | 2005-09-19 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
TW200730512A (en) | 2005-12-12 | 2007-08-16 | Astrazeneca Ab | Novel compounds |
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- 2003-01-14 KR KR10-2004-7010982A patent/KR20040073566A/ko not_active Application Discontinuation
- 2003-01-14 EP EP03700655A patent/EP1467976B1/en not_active Expired - Lifetime
- 2003-01-14 CN CNB038044811A patent/CN100357275C/zh not_active Expired - Fee Related
- 2003-01-14 AT AT03700655T patent/ATE534635T1/de active
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- 2003-01-14 AU AU2003201802A patent/AU2003201802A1/en not_active Abandoned
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Also Published As
Publication number | Publication date |
---|---|
IL162678A0 (en) | 2005-11-20 |
RU2312105C9 (ru) | 2008-06-10 |
CN1639132A (zh) | 2005-07-13 |
BR0306922A (pt) | 2004-11-09 |
WO2003059893A1 (en) | 2003-07-24 |
AR038179A1 (es) | 2005-01-05 |
US20060025423A1 (en) | 2006-02-02 |
RU2004119966A (ru) | 2005-06-10 |
EP1467976B1 (en) | 2011-11-23 |
CA2472204A1 (en) | 2003-07-24 |
ATE534635T1 (de) | 2011-12-15 |
CN100357275C (zh) | 2007-12-26 |
CO5640137A2 (es) | 2006-05-31 |
JP4504021B2 (ja) | 2010-07-14 |
HK1068885A1 (en) | 2005-05-06 |
EP1467976A1 (en) | 2004-10-20 |
AU2003201802A1 (en) | 2003-07-30 |
ES2375107T3 (es) | 2012-02-24 |
KR20040073566A (ko) | 2004-08-19 |
TWI328007B (en) | 2010-08-01 |
NZ533750A (en) | 2006-03-31 |
JP2005521650A (ja) | 2005-07-21 |
TW200303308A (en) | 2003-09-01 |
US7662825B2 (en) | 2010-02-16 |
PL371432A1 (en) | 2005-06-13 |
MXPA04006806A (es) | 2004-12-06 |
US20100081670A1 (en) | 2010-04-01 |
RU2312105C2 (ru) | 2007-12-10 |
IS7348A (is) | 2004-07-08 |
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