NZ531516A - Aminopeptidase - Google Patents

Aminopeptidase

Info

Publication number
NZ531516A
NZ531516A NZ531516A NZ53151602A NZ531516A NZ 531516 A NZ531516 A NZ 531516A NZ 531516 A NZ531516 A NZ 531516A NZ 53151602 A NZ53151602 A NZ 53151602A NZ 531516 A NZ531516 A NZ 531516A
Authority
NZ
New Zealand
Prior art keywords
aminopeptidase
sequence
dna molecule
encoding
complement
Prior art date
Application number
NZ531516A
Other languages
English (en)
Inventor
John C Joly
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to NZ544964A priority Critical patent/NZ544964A/en
Publication of NZ531516A publication Critical patent/NZ531516A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Peptides Or Proteins (AREA)
NZ531516A 2001-09-13 2002-09-12 Aminopeptidase NZ531516A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ544964A NZ544964A (en) 2001-09-13 2002-09-12 Aminopeptidase

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32235001P 2001-09-13 2001-09-13
PCT/US2002/029015 WO2003023030A2 (en) 2001-09-13 2002-09-12 Aminopeptidase

Publications (1)

Publication Number Publication Date
NZ531516A true NZ531516A (en) 2006-03-31

Family

ID=23254494

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ531516A NZ531516A (en) 2001-09-13 2002-09-12 Aminopeptidase
NZ544964A NZ544964A (en) 2001-09-13 2002-09-12 Aminopeptidase

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ544964A NZ544964A (en) 2001-09-13 2002-09-12 Aminopeptidase

Country Status (21)

Country Link
US (3) US6921659B2 (https=)
EP (1) EP1432793B1 (https=)
JP (2) JP4831932B2 (https=)
KR (2) KR100954641B1 (https=)
CN (1) CN100552023C (https=)
AT (1) ATE440134T1 (https=)
AU (1) AU2002326884B2 (https=)
BR (1) BR0212886A (https=)
CA (1) CA2460309C (https=)
CY (1) CY1109903T1 (https=)
DE (1) DE60233417D1 (https=)
DK (1) DK1432793T3 (https=)
ES (1) ES2329880T3 (https=)
HU (3) HU225346B1 (https=)
IL (2) IL160658A0 (https=)
MX (1) MXPA04002326A (https=)
NZ (2) NZ531516A (https=)
PL (1) PL206286B1 (https=)
PT (1) PT1432793E (https=)
WO (1) WO2003023030A2 (https=)
ZA (1) ZA200401752B (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60233417D1 (en) 2001-09-13 2009-10-01 Genentech Inc Aminopeptidase b2324
BRPI0507233B8 (pt) * 2004-03-11 2021-05-25 Genentech Inc processo para a produção de um polipeptídeo heterólogo em e. coli
US9637746B2 (en) 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
CN105132387A (zh) * 2008-12-22 2015-12-09 绿光生物科学公司 用于制造化合物的组合物和方法
EP2566953B1 (en) 2010-05-07 2019-01-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
EP2611922A1 (en) 2010-08-31 2013-07-10 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
CN104093848A (zh) 2011-09-09 2014-10-08 绿光生物科学公司 碳青霉烯(carbapenem)的无细胞制备
AU2014306074B2 (en) 2013-08-05 2018-08-30 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
BR112017020690A2 (pt) 2015-03-30 2018-06-26 Greenlight Biosciences Inc produção livre de células de ácido ribonucleico
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CA3020312A1 (en) 2016-04-06 2017-10-12 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN106967658B (zh) * 2017-02-23 2020-09-15 郑州大学 一种提高Fab抗体表达量的方法
KR102894284B1 (ko) 2017-10-11 2025-12-03 그린라이트 바이오사이언시스, 아이엔씨. 뉴클레오시드 트리포스페이트 및 리보핵산 생산을 위한 방법 및 조성물
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001229A1 (en) 1984-08-16 1986-02-27 Bio-Technology General Corp. Method of removing n-terminal amino acid residues from eucaryotic polypetide analogs and polypeptides produced thereby
WO1986007380A1 (fr) * 1985-06-04 1986-12-18 Takeda Chemical Industries, Ltd. Procede de preparation de polypeptides
US4865974A (en) * 1985-09-20 1989-09-12 Cetus Corporation Bacterial methionine N-terminal peptidase
ATE122391T1 (de) 1987-01-30 1995-05-15 Harvard College Periplasmische protease-mutanten von escherichia coli.
US4946783A (en) * 1987-01-30 1990-08-07 President And Fellows Of Harvard College Periplasmic protease mutants of Escherichia coli
JPH01181796A (ja) * 1988-01-14 1989-07-19 Ajinomoto Co Inc 組換えｄｎａ法を用いたポリペプチドの製造法
JP2844870B2 (ja) * 1989-07-21 1999-01-13 味の素株式会社 組み替えｄｎａ法によるポリペプチドの製造法
US5508192A (en) * 1990-11-09 1996-04-16 Board Of Regents, The University Of Texas System Bacterial host strains for producing proteolytically sensitive polypeptides
US5304472A (en) * 1992-11-20 1994-04-19 Genentech, Inc. Method of controlling polypeptide production in bacterial cells
US5573923A (en) * 1993-12-22 1996-11-12 Eli Lilly And Company Method for removing N-terminal dipeptides from precursor polypeptides with immobilized dipeptidylaminopeptidase from dictyostelium discoideum
US6127144A (en) * 1993-12-23 2000-10-03 Cangene Corporation Method for expression of proteins in bacterial host cells
US5789199A (en) * 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5639635A (en) * 1994-11-03 1997-06-17 Genentech, Inc. Process for bacterial production of polypeptides
KR100369839B1 (ko) * 1997-02-28 2003-06-12 주식회사 엘지생명과학 바실러스리케니포미스균주에서유래한아미노펩티다제,그의제조방법및이를이용한천연형단백질의제조방법
WO2000034452A1 (en) * 1998-12-07 2000-06-15 Novozymes A/S Glucoamylases with n-terminal extensions
KR20020011399A (ko) * 1999-04-30 2002-02-08 파마시아 코포레이션 에어로모나스 아미노펩티다제로 ν-말단 알라닌 잔기를폴리펩티드로부터 제거하는 방법
KR100400638B1 (ko) 2000-12-06 2003-10-08 주식회사 엘지생명과학 재조합 인간 성장호르몬 유사체의 분리방법
DE60233417D1 (en) 2001-09-13 2009-10-01 Genentech Inc Aminopeptidase b2324

Also Published As

Publication number Publication date
JP2005502359A (ja) 2005-01-27
KR20090018142A (ko) 2009-02-19
US20080160572A1 (en) 2008-07-03
CN100552023C (zh) 2009-10-21
EP1432793B1 (en) 2009-08-19
KR100954641B1 (ko) 2010-04-27
DK1432793T3 (da) 2009-12-07
US20030124664A1 (en) 2003-07-03
ATE440134T1 (de) 2009-09-15
PL368463A1 (en) 2005-04-04
AU2002326884B2 (en) 2007-10-18
KR100956907B1 (ko) 2010-05-11
NZ544964A (en) 2007-08-31
EP1432793A4 (en) 2006-05-24
ES2329880T3 (es) 2009-12-02
US20060019341A1 (en) 2006-01-26
IL160658A0 (en) 2004-08-31
HU225243B1 (en) 2006-08-28
HU0600310D0 (en) 2006-06-28
CA2460309A1 (en) 2003-03-20
BR0212886A (pt) 2004-10-13
HU225346B1 (en) 2006-10-28
US7229787B2 (en) 2007-06-12
JP2011177189A (ja) 2011-09-15
KR20040041611A (ko) 2004-05-17
CN1555412A (zh) 2004-12-15
US7632658B2 (en) 2009-12-15
JP4831932B2 (ja) 2011-12-07
US6921659B2 (en) 2005-07-26
HUP0401869A2 (hu) 2004-12-28
CY1109903T1 (el) 2014-09-10
WO2003023030A2 (en) 2003-03-20
PL206286B1 (pl) 2010-07-30
IL160658A (en) 2009-05-04
CA2460309C (en) 2012-07-10
ZA200401752B (en) 2005-05-25
WO2003023030A3 (en) 2003-07-10
PT1432793E (pt) 2009-11-24
HU225430B1 (en) 2006-11-28
DE60233417D1 (en) 2009-10-01
HU0600309D0 (en) 2006-06-28
JP5372061B2 (ja) 2013-12-18
MXPA04002326A (es) 2004-06-29
HK1062695A1 (en) 2004-11-19
HUP0401869A3 (en) 2005-06-28
EP1432793A2 (en) 2004-06-30

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