NZ530161A - Positive modulators of nicotinic receptor agonists - Google Patents
Positive modulators of nicotinic receptor agonistsInfo
- Publication number
- NZ530161A NZ530161A NZ530161A NZ53016100A NZ530161A NZ 530161 A NZ530161 A NZ 530161A NZ 530161 A NZ530161 A NZ 530161A NZ 53016100 A NZ53016100 A NZ 53016100A NZ 530161 A NZ530161 A NZ 530161A
- Authority
- NZ
- New Zealand
- Prior art keywords
- hydrogen
- alkyl
- compound
- nicotinic receptor
- compounds
- Prior art date
Links
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- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 title abstract description 25
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- 239000000018 receptor agonist Substances 0.000 title abstract description 16
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- -1 R2 is H Chemical group 0.000 claims abstract description 9
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- 238000000034 method Methods 0.000 claims description 21
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- VONWPEXRCLHKRJ-UHFFFAOYSA-N 2-chloro-n-phenylacetamide Chemical compound ClCC(=O)NC1=CC=CC=C1 VONWPEXRCLHKRJ-UHFFFAOYSA-N 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
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Applications Claiming Priority (1)
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| SE9903997A SE9903997D0 (sv) | 1999-11-03 | 1999-11-03 | New compounds |
Publications (1)
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| NZ530161A true NZ530161A (en) | 2005-08-26 |
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| NZ530161A NZ530161A (en) | 1999-11-03 | 2000-11-01 | Positive modulators of nicotinic receptor agonists |
| NZ518450A NZ518450A (en) | 1999-11-03 | 2000-11-01 | Indole derivatives and their use as positive modulators of nicotinic receptor agonists |
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| Application Number | Title | Priority Date | Filing Date |
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| NZ518450A NZ518450A (en) | 1999-11-03 | 2000-11-01 | Indole derivatives and their use as positive modulators of nicotinic receptor agonists |
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| EP (1) | EP1230216A1 (enExample) |
| JP (1) | JP2003513071A (enExample) |
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| CA (1) | CA2387745A1 (enExample) |
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| SE9903998D0 (sv) * | 1999-11-03 | 1999-11-03 | Astra Ab | New compounds |
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| DE10234424A1 (de) * | 2002-07-29 | 2004-02-12 | Bayer Ag | Benzothiophen-, Benzofuran- und Indolharnstoffe |
| EP2305664A1 (en) | 2002-08-30 | 2011-04-06 | Memory Pharmaceuticals Corporation | Anabaseine derivatives useful in the treatment of neurodegeneratives diseases |
| CA2499128C (en) | 2002-09-25 | 2012-07-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
| CN103724343A (zh) | 2004-03-25 | 2014-04-16 | 记忆药物公司 | 吲唑、苯并噻唑、苯并异噻唑、苯并异噁唑及其制备和用途 |
| CN101247853B (zh) | 2005-04-13 | 2014-11-12 | 轴突公司 | 具有nos抑制活性的取代的吲哚化合物 |
| US20070134169A1 (en) * | 2005-12-11 | 2007-06-14 | Rabinoff Michael D | Methods for smoking cessation or alcohol cessation or other addiction cessation |
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| EA201000808A1 (ru) | 2007-11-16 | 2011-04-29 | Ньюраксон, Инк. | Индольные соединения и способы лечения висцеральной боли |
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| KR930702334A (ko) * | 1990-09-13 | 1993-09-08 | 데이비드 로버트 | 5 하이드록시트립타민 수용체 길항제로서의 인돌우레아 |
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| FR2722686B1 (fr) * | 1994-07-22 | 1996-08-30 | Oreal | Set, procede, dispositif et composition de teinture des fibres keratiniques |
| US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
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- 2000-11-01 BR BR0015195-5A patent/BR0015195A/pt not_active IP Right Cessation
- 2000-11-01 IL IL14909800A patent/IL149098A0/xx unknown
- 2000-11-01 AU AU14264/01A patent/AU783507B2/en not_active Ceased
- 2000-11-01 CO CO00083175A patent/CO5251458A1/es not_active Application Discontinuation
- 2000-11-01 US US10/111,027 patent/US6750242B1/en not_active Expired - Fee Related
- 2000-11-01 NZ NZ530161A patent/NZ530161A/en unknown
- 2000-11-01 WO PCT/SE2000/002148 patent/WO2001032619A1/en not_active Ceased
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- 2000-11-01 JP JP2001534771A patent/JP2003513071A/ja not_active Abandoned
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| CA2387745A1 (en) | 2001-05-10 |
| WO2001032619A1 (en) | 2001-05-10 |
| CO5251458A1 (es) | 2003-02-28 |
| AU1426401A (en) | 2001-05-14 |
| KR20020063176A (ko) | 2002-08-01 |
| NO323076B1 (no) | 2006-12-27 |
| NO20022009D0 (no) | 2002-04-26 |
| US6750242B1 (en) | 2004-06-15 |
| SE9903997D0 (sv) | 1999-11-03 |
| NZ518450A (en) | 2004-04-30 |
| MXPA02004232A (es) | 2002-10-17 |
| JP2003513071A (ja) | 2003-04-08 |
| IL149098A0 (en) | 2002-11-10 |
| ZA200203171B (en) | 2003-09-23 |
| AU783507B2 (en) | 2005-11-03 |
| EP1230216A1 (en) | 2002-08-14 |
| BR0015195A (pt) | 2002-06-18 |
| NO20022009L (no) | 2002-07-02 |
| CN1239482C (zh) | 2006-02-01 |
| CN1387512A (zh) | 2002-12-25 |
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