NZ528478A - N-acetylocysteine compositions and methods for the treatment and prevention of drug toxicity - Google Patents
N-acetylocysteine compositions and methods for the treatment and prevention of drug toxicityInfo
- Publication number
- NZ528478A NZ528478A NZ528478A NZ52847802A NZ528478A NZ 528478 A NZ528478 A NZ 528478A NZ 528478 A NZ528478 A NZ 528478A NZ 52847802 A NZ52847802 A NZ 52847802A NZ 528478 A NZ528478 A NZ 528478A
- Authority
- NZ
- New Zealand
- Prior art keywords
- acetylcysteine
- therapeutic
- acetaminophen
- pharmaceutically acceptable
- combination
- Prior art date
Links
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- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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Landscapes
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| PCT/US2002/009442 WO2002078627A2 (en) | 2001-03-30 | 2002-03-28 | N-acetylcysteine compositions and methods for the treatment and prevention of drug toxicity |
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| US8778979B2 (en) | 2005-04-05 | 2014-07-15 | Yale University | Glutamate agents in the treatment of mental disorders |
| US8993627B2 (en) | 2005-04-21 | 2015-03-31 | Sentient Lifesciences, Inc. | N-acetylcysteine amide (NAC amide) for the treatment of diseases and conditions associated with oxidative stress |
| US8148356B2 (en) | 2005-08-24 | 2012-04-03 | Cumberland Pharmaceuticals, Inc. | Acetylcysteine composition and uses therefor |
| RU2302236C2 (ru) * | 2005-09-09 | 2007-07-10 | Государственное учреждение научно-исследовательский институт Гриппа Российской академии медицинских наук (ГУ НИИ Гриппа РАМН) | Средство, обладающее антигипоксической и цитопротекторной активностями, используемое для снижения токсичности ремантадина при лечении гриппозной инфекции |
| US20070098790A1 (en) * | 2005-10-31 | 2007-05-03 | David Jiang | Nutritional supplement for the enhancement of the health of the liver |
| US20080139654A1 (en) * | 2006-12-09 | 2008-06-12 | Eric Mott Soderling | Acetaminophen compositions having minimized side effects including reduced hepatotoxicity |
| EP2291182A1 (en) * | 2008-05-13 | 2011-03-09 | Genmedica Therapeutics SL | Salicylate conjugates useful for treating metabolic disorders |
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| CN102421424A (zh) * | 2009-03-16 | 2012-04-18 | 根梅迪卡治疗公司 | 用于治疗代谢性疾病的组合疗法 |
| WO2010132864A1 (en) * | 2009-05-15 | 2010-11-18 | Intermune, Inc. | Methods of treating hiv patients with anti-fibrotics |
| US20120122787A1 (en) * | 2009-07-10 | 2012-05-17 | Rong Li | Methods for treating polycystic kidney disease (pkd) or other cyst forming diseases |
| EP2453743B1 (en) | 2009-07-15 | 2017-04-12 | The Board of Trustees of The Leland Stanford Junior University | N-acetyl cysteine compositions and their use in improving the therapeutic efficacy of acetaminophen |
| DE102011006425A1 (de) | 2010-03-31 | 2011-10-06 | Awd.Pharma Gmbh & Co. Kg | Pharmazeutische Zubereitung und deren Verwendung |
| US8466197B2 (en) | 2010-12-14 | 2013-06-18 | Genmedica Therapeutics Sl | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders |
| US20140135396A1 (en) * | 2011-07-05 | 2014-05-15 | Beth Israel Deaconess Medical Center, Inc. | Treatment of Acetaminophen-Induced Liver Damage by the Administration of Modulators of Nitric Oxide |
| US8747894B2 (en) | 2012-05-08 | 2014-06-10 | Alpex Pharma S.A. | Effervescent compositions containing N-acetylcysteine |
| EP2854798A4 (en) | 2012-05-24 | 2016-05-11 | Mograbi Josef | COMPOSITIONS WITH ISOSILYBIN B FOR THE TREATMENT AND PREVENTION OF ACTIVE-INDUCED TOXICITY |
| PL3639828T3 (pl) | 2013-12-24 | 2022-05-02 | Virginia Commonwealth University | Zastosowanie utlenowanych siarczanów cholesterolu (ocs) w leczeniu ostrej niewydolności wątroby |
| WO2016123223A1 (en) * | 2015-01-27 | 2016-08-04 | Florengale, Llc | Healing topical composition |
| HK1249035A1 (zh) * | 2015-05-27 | 2018-10-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | 降低成像後胰腺炎风险的组合物和方法 |
| BR112017025499A2 (pt) | 2015-05-28 | 2018-08-07 | Baylor College Medicine | benefícios da suplementação com n-acetil cisteína e glicina para melhorar os níveis de glutationa |
| EP3402475B1 (en) * | 2016-01-11 | 2021-10-20 | Egetis Therapeutics AB | Methods and formulations for treatment of and/or protection against acute liver failure and other hepatotoxic conditions |
| CA3012837A1 (en) | 2016-02-04 | 2017-08-10 | Czap Research And Development, Llc | Controlled-release and stratified cyclodextrin inclusion complex vehicles |
| DK3554491T3 (en) | 2016-12-15 | 2023-05-15 | Zambon Spa | N-acetylcystein til anvendelse som antibakterielt middel |
| US11040007B2 (en) * | 2017-01-24 | 2021-06-22 | Woosung Pharmaceutical Co., Ltd. | Injection composition containing acetaminophen |
| EP3901620A4 (en) * | 2018-12-21 | 2022-02-16 | FUJIFILM Corporation | PHOTOTOXICITY OR PHOTOALLERGY MEASUREMENT PROCEDURE AND REAGENT FOR USE IN THAT MEASUREMENT |
| US11590090B2 (en) | 2019-09-14 | 2023-02-28 | Anzen Pharmaceuticals, LLC | Acetaminophen formulation with protection against toxic effects of overdose |
| GB2588172B (en) * | 2019-10-11 | 2023-05-24 | Blackhawk Partners Ltd | A pharmaceutical composition comprising cannabinoid |
| CN113288890B (zh) * | 2021-06-21 | 2022-02-22 | 南方医科大学南方医院 | N-乙酰-l-半胱氨酸在制备预防和/或治疗运动损伤的药物中的应用 |
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| DE3616923A1 (de) | 1986-05-20 | 1987-11-26 | Nattermann A & Cie | Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on |
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| IT1248995B (it) * | 1990-06-26 | 1995-02-11 | Italfarmaco Spa | Composizioni farmaceutiche a base di sali ferrosi |
| US5474757A (en) * | 1992-10-16 | 1995-12-12 | Rutgers University | Prevention of acetaminophen overdose toxicity with organosulfur compounds |
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| US5475757A (en) * | 1994-06-07 | 1995-12-12 | At&T Corp. | Secure data transmission method |
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| US5750493A (en) * | 1995-08-30 | 1998-05-12 | Raymond F. Schinazi | Method to improve the biological and antiviral activity of protease inhibitors |
| FR2744917B1 (fr) | 1996-02-16 | 1998-04-10 | Kouchner Gerard | Composition therapeutique a base d'acetaminophene |
| US5837729A (en) * | 1996-04-26 | 1998-11-17 | Metatron, Inc. | Methods for treating and preventing HIV infection using acetaminophen and derivatives thereof |
| US5962421A (en) * | 1996-05-16 | 1999-10-05 | Zambon, S.A. | Pharmacological association between N-acetylcysteine and levulose for preventing cellular death and related diseases |
| CA2294247C (en) * | 1997-07-01 | 2004-10-26 | Atherogenics, Inc. | Antioxidant enhancement of therapy for hyperproliferative conditions |
| CA2355859A1 (en) * | 1999-01-04 | 2000-07-13 | Ml Laboratories Plc | Gene therapy-1 |
| IT1312086B1 (it) * | 1999-04-21 | 2002-04-04 | Zambon Spa | Uso della nac per la preparazione di un medicamento adatto allasomministrazione endovenosa per la prevenzione dello stress |
| DE10112325A1 (de) | 2001-03-13 | 2002-10-02 | Fresenius Kabi De Gmbh | Lagerstabile Fertiginfusionslösungen des Paracetamols |
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2001
- 2001-04-11 US US09/833,228 patent/US6566401B2/en not_active Expired - Lifetime
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2002
- 2002-03-28 RU RU2003131876/15A patent/RU2291689C2/ru not_active IP Right Cessation
- 2002-03-28 NZ NZ528478A patent/NZ528478A/en not_active IP Right Cessation
- 2002-03-28 WO PCT/US2002/009442 patent/WO2002078627A2/en not_active Ceased
- 2002-03-28 CN CNB028077334A patent/CN100464743C/zh not_active Expired - Fee Related
- 2002-03-28 IL IL15818102A patent/IL158181A0/xx unknown
- 2002-03-28 CA CA2442168A patent/CA2442168C/en not_active Expired - Lifetime
- 2002-03-28 ES ES02725376.4T patent/ES2550094T3/es not_active Expired - Lifetime
- 2002-03-28 EP EP02725376.4A patent/EP1379232B1/en not_active Revoked
- 2002-03-28 BR BRPI0208563-1A patent/BR0208563A/pt not_active IP Right Cessation
- 2002-03-28 JP JP2002576895A patent/JP2005508840A/ja active Pending
- 2002-03-28 MX MXPA03008904A patent/MXPA03008904A/es active IP Right Grant
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Also Published As
| Publication number | Publication date |
|---|---|
| US7723389B2 (en) | 2010-05-25 |
| JP2015078185A (ja) | 2015-04-23 |
| CA2442168C (en) | 2012-05-29 |
| WO2002078627A3 (en) | 2003-09-18 |
| CA2442168A1 (en) | 2002-10-10 |
| CN1507350A (zh) | 2004-06-23 |
| RU2003131876A (ru) | 2005-04-10 |
| AU2002255942B2 (en) | 2007-07-05 |
| IL158181A0 (en) | 2004-03-28 |
| RU2291689C2 (ru) | 2007-01-20 |
| US6566401B2 (en) | 2003-05-20 |
| CN100464743C (zh) | 2009-03-04 |
| JP2011225610A (ja) | 2011-11-10 |
| WO2002078627A2 (en) | 2002-10-10 |
| IL158181A (en) | 2012-04-30 |
| US20020142991A1 (en) | 2002-10-03 |
| EP1379232B1 (en) | 2015-07-29 |
| JP2005508840A (ja) | 2005-04-07 |
| EP1379232A4 (en) | 2008-04-23 |
| ES2550094T3 (es) | 2015-11-04 |
| US20030069311A1 (en) | 2003-04-10 |
| BR0208563A (pt) | 2006-02-21 |
| EP1379232A2 (en) | 2004-01-14 |
| MXPA03008904A (es) | 2005-03-07 |
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