NZ511408A - Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy - Google Patents
Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapyInfo
- Publication number
- NZ511408A NZ511408A NZ511408A NZ51140899A NZ511408A NZ 511408 A NZ511408 A NZ 511408A NZ 511408 A NZ511408 A NZ 511408A NZ 51140899 A NZ51140899 A NZ 51140899A NZ 511408 A NZ511408 A NZ 511408A
- Authority
- NZ
- New Zealand
- Prior art keywords
- flt4
- compound
- fragment
- polypeptide
- cells
- Prior art date
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US6818220B1 (en) | 1994-11-14 | 2004-11-16 | Licentia Ltd. | Vascular endothelial growth factor C (VEGF-C) protein and gene mutants thereof, and uses thereof |
| US6361946B1 (en) | 1997-02-05 | 2002-03-26 | Licentia Ltd | Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof |
| US7423125B2 (en) | 1995-08-01 | 2008-09-09 | Vegenics Limited | Antibodies to VEGF-C |
| AU710696C (en) | 1995-09-08 | 2002-10-24 | Genentech Inc. | VEGF-related protein |
| US7125714B2 (en) | 1997-02-05 | 2006-10-24 | Licentia Ltd. | Progenitor cell materials and methods |
| CA2345276C (en) * | 1998-10-09 | 2011-03-29 | Ludwig Institute For Cancer Research | Flt4 (vegfr-3) as a target for tumor imaging and anti-tumor therapy |
| US7223724B1 (en) | 1999-02-08 | 2007-05-29 | Human Genome Sciences, Inc. | Use of vascular endothelial growth factor to treat photoreceptor cells |
| EP1553414A1 (en) * | 1999-04-13 | 2005-07-13 | Medarex, Inc. | Methods for the diagnosis and treatment of metastatic prostate tumors |
| EP1259626B1 (en) | 2000-02-25 | 2007-10-31 | Ludwig Institute For Cancer Research | Materials and methods involving hybrid vascular endothelial growth factor dnas and proteins and screening methods for modulators |
| CA2386103A1 (en) | 2000-08-04 | 2002-02-14 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| US7611711B2 (en) | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
| AU2002248372B8 (en) * | 2001-01-19 | 2008-03-20 | Vegenics Limited | FLT4(VEGFR-3) as a target for tumor imaging and anti-tumor therapy |
| DK1385864T3 (da) | 2001-04-13 | 2010-08-16 | Human Genome Sciences Inc | Anti-VEGF-2-antistoffer |
| US9994853B2 (en) | 2001-05-18 | 2018-06-12 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
| US7109165B2 (en) | 2001-05-18 | 2006-09-19 | Sirna Therapeutics, Inc. | Conjugates and compositions for cellular delivery |
| US20040242851A1 (en) * | 2001-06-26 | 2004-12-02 | Zhenping Zhu | Bispecific antibodies that bind to vegf receptors |
| US20030113324A1 (en) * | 2001-10-01 | 2003-06-19 | Kari Alitalo | Neuropilin/VEGF-C/VEGFR-3 materials and methods |
| AU2003207708A1 (en) * | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
| US9657294B2 (en) | 2002-02-20 | 2017-05-23 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
| US9181551B2 (en) | 2002-02-20 | 2015-11-10 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
| US8003613B2 (en) | 2003-11-17 | 2011-08-23 | University Of Florida Research Foundation, Inc. | Methods and compositions for inducing apoptosis |
| CA2554212A1 (en) | 2004-02-10 | 2005-08-25 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional sina) |
| WO2005087177A2 (en) | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same |
| US10508277B2 (en) | 2004-05-24 | 2019-12-17 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
| WO2007022287A2 (en) | 2005-08-15 | 2007-02-22 | Vegenics Limited | Modified vegf and pdgf with improved angiogenic properties |
| US9201063B2 (en) | 2006-11-16 | 2015-12-01 | General Electric Company | Sequential analysis of biological samples |
| US7629125B2 (en) | 2006-11-16 | 2009-12-08 | General Electric Company | Sequential analysis of biological samples |
| US8305579B2 (en) | 2006-11-16 | 2012-11-06 | Thomas Pirrie Treynor | Sequential analysis of biological samples |
| US9677125B2 (en) | 2009-10-21 | 2017-06-13 | General Electric Company | Detection of plurality of targets in biological samples |
| WO2011106697A1 (en) | 2010-02-25 | 2011-09-01 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
| DK2632472T3 (en) | 2010-10-29 | 2018-03-19 | Sirna Therapeutics Inc | RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA) |
| WO2014064203A1 (en) | 2012-10-26 | 2014-05-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Lyve-1 antagonists for preventing or treating a pathological condition associated with lymphangiogenesis |
| WO2014124487A1 (en) | 2013-02-18 | 2014-08-21 | Vegenics Pty Limited | Ligand binding molecules and uses thereof |
| EP2994758B1 (en) | 2013-05-08 | 2017-12-20 | Opthea Limited | Biomarkers for age-related macular degeneration (amd) |
| KR102131370B1 (ko) | 2013-10-18 | 2020-07-08 | 삼성전자주식회사 | Vegf-c에 특이적으로 결합하는 폴리펩타이드 및 그의 용도 |
| CN114262683B (zh) * | 2022-03-01 | 2022-06-17 | 中国科学院动物研究所 | 一种表达vegfr3 d2多肽的细菌制剂及其构建方法和应用 |
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| US5231001A (en) * | 1991-03-14 | 1993-07-27 | The United States Of America As Represented By The Department Of Health And Human Services | Trk tyrosine kinase receptor is the physiological receptor for nerve growth factor |
| US5185438A (en) * | 1991-04-02 | 1993-02-09 | The Trustees Of Princeton University | Nucleic acids encoding hencatoporetic stem cell receptor flk-2 |
| US5367057A (en) * | 1991-04-02 | 1994-11-22 | The Trustees Of Princeton University | Tyrosine kinase receptor flk-2 and fragments thereof |
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| CA2078539C (en) * | 1991-09-18 | 2005-08-02 | Kenya Shitara | Process for producing humanized chimera antibody |
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| WO1998033917A1 (en) | 1994-11-14 | 1998-08-06 | The Ludwig Institute For Cancer Research | Vascular endothelial growth factor c (vegf-c) protein and gene, mutants thereof, and uses thereof |
| AU710696C (en) * | 1995-09-08 | 2002-10-24 | Genentech Inc. | VEGF-related protein |
| US6100071A (en) * | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
| WO1998005293A2 (en) * | 1996-08-02 | 1998-02-12 | The Children's Medical Center Corporation | Method of regulating the female reproductive system through angiogenesis inhibitors |
| DK2107109T3 (da) | 1996-08-23 | 2012-09-24 | Vegenics Pty Ltd | Rekombinant vaskulær endotelcelle-vækstfaktor D (VEGF-D) |
| EP1054687B8 (en) | 1997-12-24 | 2008-07-16 | Vegenics Limited | Expression vectors and cell lines expressing vascular endothelial growth factor d, and method of treating melanomas |
| CA2345276C (en) * | 1998-10-09 | 2011-03-29 | Ludwig Institute For Cancer Research | Flt4 (vegfr-3) as a target for tumor imaging and anti-tumor therapy |
| KR101681886B1 (ko) | 2015-04-06 | 2016-12-12 | 서울대학교산학협력단 | 지르코니아 결합능을 가지는 펩타이드 |
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- 1999-10-08 AT AT99956525T patent/ATE489108T1/de active
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- 1999-10-08 JP JP2000575533A patent/JP4841724B2/ja not_active Expired - Fee Related
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- 1999-10-08 DK DK99956525.2T patent/DK1119371T3/da active
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Also Published As
| Publication number | Publication date |
|---|---|
| AU774266B2 (en) | 2004-06-24 |
| CN1329504A (zh) | 2002-01-02 |
| JP2011121957A (ja) | 2011-06-23 |
| JP2012019790A (ja) | 2012-02-02 |
| ES2357406T3 (es) | 2011-04-26 |
| WO2000021560A9 (en) | 2000-09-21 |
| NO20011759L (no) | 2001-06-11 |
| JP5784310B2 (ja) | 2015-09-24 |
| AU2004208675A1 (en) | 2004-09-30 |
| US20150158928A1 (en) | 2015-06-11 |
| DK1119371T3 (da) | 2011-03-07 |
| JP2013209382A (ja) | 2013-10-10 |
| AU1312100A (en) | 2000-05-01 |
| AU2004208675B2 (en) | 2006-03-02 |
| ATE489108T1 (de) | 2010-12-15 |
| JP5642637B2 (ja) | 2014-12-17 |
| CA2345276C (en) | 2011-03-29 |
| NZ529063A (en) | 2005-07-29 |
| JP2002527404A (ja) | 2002-08-27 |
| JP2015157829A (ja) | 2015-09-03 |
| DE69942981D1 (de) | 2011-01-05 |
| EP1119371B1 (en) | 2010-11-24 |
| EP1119371A1 (en) | 2001-08-01 |
| NO20011759D0 (no) | 2001-04-06 |
| WO2000021560A1 (en) | 2000-04-20 |
| US8444957B2 (en) | 2013-05-21 |
| US20100278736A1 (en) | 2010-11-04 |
| US20140072511A1 (en) | 2014-03-13 |
| JP4841724B2 (ja) | 2011-12-21 |
| CA2345276A1 (en) | 2000-04-20 |
| CN100340291C (zh) | 2007-10-03 |
| US20160184405A1 (en) | 2016-06-30 |
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