NZ310344A - Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders - Google Patents

Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders

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Publication number
NZ310344A
NZ310344A NZ310344A NZ31034496A NZ310344A NZ 310344 A NZ310344 A NZ 310344A NZ 310344 A NZ310344 A NZ 310344A NZ 31034496 A NZ31034496 A NZ 31034496A NZ 310344 A NZ310344 A NZ 310344A
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NZ
New Zealand
Prior art keywords
compound
comoound
nhj
oct
received
Prior art date
Application number
NZ310344A
Other languages
English (en)
Inventor
Alan L Mueller
Scott T Moe
Manuel F Balandrin
Eric G Delmar
Bradford C Vanwagenen
Linda D Artman
Robert M Barmore
Daryl L Smith
Original Assignee
Npc Pharmaceuticals Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23926692&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ310344(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Npc Pharmaceuticals Inc filed Critical Npc Pharmaceuticals Inc
Publication of NZ310344A publication Critical patent/NZ310344A/en

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
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NZ310344A 1995-06-07 1996-06-07 Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders NZ310344A (en)

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DK0831799T3 (da) 2003-08-11
DE69627852D1 (de) 2003-06-05
BR9609019A (pt) 1999-07-06
CN1192679A (zh) 1998-09-09
AU716122B2 (en) 2000-02-17
US6051610A (en) 2000-04-18
JPH11506469A (ja) 1999-06-08
PL323871A1 (en) 1998-04-27
DE69627852T2 (de) 2004-02-26
KR100430022B1 (ko) 2004-07-16
EP0831799B1 (en) 2003-05-02
ATE238782T1 (de) 2003-05-15
WO1996040097A1 (en) 1996-12-19
ES2197945T3 (es) 2004-01-16
PT831799E (pt) 2003-09-30
CN1153568C (zh) 2004-06-16
HK1008980A1 (en) 1999-05-21
RU2246300C2 (ru) 2005-02-20
AU6112596A (en) 1996-12-30
EP0831799A1 (en) 1998-04-01
KR19990022588A (ko) 1999-03-25
US6071970A (en) 2000-06-06
CA2223978A1 (en) 1996-12-19
PL185492B1 (pl) 2003-05-30

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