NZ277946A - Apoptosis modulating protein and nucleotide sequence compositions using bcl-2 homologs termed cdn-1, cdn-2 and cdn3 - Google Patents

Apoptosis modulating protein and nucleotide sequence compositions using bcl-2 homologs termed cdn-1, cdn-2 and cdn3

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Publication number
NZ277946A
NZ277946A NZ277946A NZ27794694A NZ277946A NZ 277946 A NZ277946 A NZ 277946A NZ 277946 A NZ277946 A NZ 277946A NZ 27794694 A NZ27794694 A NZ 27794694A NZ 277946 A NZ277946 A NZ 277946A
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NZ
New Zealand
Prior art keywords
cdn
composition according
nucleotide sequence
cell
depicted
Prior art date
Application number
NZ277946A
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English (en)
Inventor
Michael C Kiefer
Philip J Barr
Original Assignee
Lxr Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Publication of NZ277946A publication Critical patent/NZ277946A/en

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747Apoptosis related proteins
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2267/02Animal zootechnically ameliorated
    • A01K2267/025Animal producing cells or organs for transplantation
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    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
NZ277946A 1993-11-30 1994-11-30 Apoptosis modulating protein and nucleotide sequence compositions using bcl-2 homologs termed cdn-1, cdn-2 and cdn3 NZ277946A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16006793A 1993-11-30 1993-11-30
US32015794A 1994-10-07 1994-10-07
PCT/US1994/013930 WO1995015084A1 (en) 1993-11-30 1994-11-30 Novel apoptosis-modulating proteins, dna encoding the proteins and methods of use thereof

Publications (1)

Publication Number Publication Date
NZ277946A true NZ277946A (en) 1998-03-25

Family

ID=26856568

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ277946A NZ277946A (en) 1993-11-30 1994-11-30 Apoptosis modulating protein and nucleotide sequence compositions using bcl-2 homologs termed cdn-1, cdn-2 and cdn3

Country Status (14)

Country Link
US (7) US6586395B1 (de)
EP (1) EP0731636B1 (de)
JP (4) JP4129055B2 (de)
CN (1) CN1139871A (de)
AT (1) ATE315643T1 (de)
AU (1) AU688839B2 (de)
CA (1) CA2177827C (de)
DE (1) DE69434614T2 (de)
ES (1) ES2256843T3 (de)
FI (1) FI962247A (de)
HU (1) HUT74276A (de)
NO (1) NO962188L (de)
NZ (1) NZ277946A (de)
WO (1) WO1995015084A1 (de)

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EP0731636B1 (de) 1993-11-30 2006-01-11 Tanox, Inc. Cdn apoptosis modulierende proteine, sie kodierende dns und verfahren zu ihrer verwendung
US5998131A (en) * 1994-10-07 1999-12-07 Lxr Biotechnology, Inc. Screening methods for the identification of compounds capable of abrogating BaK-BHRF-1 protein interactions
JPH1189573A (ja) * 1994-10-14 1999-04-06 Yutaka Shindo アポトーシス関与遺伝子
WO1996033416A1 (en) * 1995-04-20 1996-10-24 Lxr Biotechnology Inc. Methods of screening for therapeutic agents using novel apoptosis-modulating proteins
AU6165598A (en) * 1997-02-18 1998-09-08 Lxr Biotechnology Inc. Bak promotor expression system
US6441135B1 (en) * 1997-03-20 2002-08-27 Tanox, Inc. Bak binding protein, DNA encoding the protein, and methods of use thereof
US20030215445A1 (en) 1997-05-23 2003-11-20 Ginette Serrero Methods and compositions for inhibiting the growth of hematopoietic malignant cells
US20100111928A1 (en) * 1997-05-23 2010-05-06 A & G Pharmaceutical, Inc. Methods and kits for diagnosis tumorgenicity
US6218144B1 (en) * 1997-06-30 2001-04-17 The Board Of Trustees Of The Leland Stanford Junior University Costal2 genes and their uses
US6641998B2 (en) * 1997-10-10 2003-11-04 Stratagene Methods and kits to enrich for desired nucleic acid sequences
DE69937835T2 (de) * 1998-09-24 2009-01-02 Promega Corp., Madison Antikörper für apoptosemarker und anwendungsverfahren
US6570002B1 (en) 1999-02-26 2003-05-27 The Johns Hopkins University Inhibitor of programmed cell death
US6737511B1 (en) * 1999-08-16 2004-05-18 The United States Of America As Represented By The Department Of Health And Human Services Receptor-mediated uptake of an extracellular BCL-xL fusion protein inhibits apoptosis
US20010053769A1 (en) 2000-01-21 2001-12-20 Christiane Ferran Use of pro-apoptotic factors in treatment of atherosclerosis
EP1349929A2 (de) * 2000-07-14 2003-10-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Apoptose-induzierende dna-sequenzen
WO2002074908A2 (en) * 2001-03-02 2002-09-26 Mds Proteomics, Inc. Methods and reagents for regulating apoptosis
EP1253200A1 (de) * 2001-04-25 2002-10-30 Société des Produits Nestlé S.A. Kakao-Polypeptide und ihre Anwendung zur Herstellung von Kakao- und Schokoladenaroma
CN100352510C (zh) * 2001-10-03 2007-12-05 拜奥尼茨生命科学公司 可用于治疗的三甘醇胆甾烯基寡核苷酸
US7411045B2 (en) * 2002-11-19 2008-08-12 A&G Pharmaceutical, Inc. Autocrine growth factor receptor antibodies and methods
WO2004050858A2 (en) * 2002-12-04 2004-06-17 Diadexus, Inc. Compositions, splice variants and methods relating to colon specific genes and proteins
WO2004072225A2 (en) * 2003-02-12 2004-08-26 Ramot At Tel Aviv University Ltd. Transgenic fungi expressing bcl-2 and methods of using bcl-2 or portions thereof for improving biomass production, survival, longevity, stress resistance and pathogenicity of fungi
KR20060070491A (ko) * 2003-06-23 2006-06-23 에이 앤드 지 파마슈티컬즈, 인코포레이티드 항종양 요법에 대한 종양 세포의 감수성 회복 및 세포 사멸유도를 위한 조성물 및 방법
WO2005011590A2 (en) * 2003-08-01 2005-02-10 A & G Pharmaceutical, Inc. Compositions and methods for restoring sensitivity to treatment with her2 antagonists
HUE031122T2 (en) * 2005-10-31 2017-07-28 Oncomed Pharm Inc Preparations and methods for the treatment of cancer based on human FZD receptors
WO2011056886A2 (en) * 2009-11-03 2011-05-12 The Johns Hopkins University Method and composition for generating programmed cell death resistant algal cells
EP2418286A1 (de) * 2010-08-10 2012-02-15 QIAGEN GmbH Verbessertes Verfahren zur isothermalen Amplifikation von Nukleinsäuren
US20130166458A1 (en) * 2011-12-22 2013-06-27 Embraer S.A. System and method for remote and automatic assessment of structural damage and repair
US20230392166A1 (en) * 2020-10-21 2023-12-07 Wisconsin Alumni Research Foundation Anti-apoptotic vector and method of using the same

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AU2515992A (en) * 1991-08-20 1993-03-16 Genpharm International, Inc. Gene targeting in animal cells using isogenic dna constructs
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5395767A (en) 1992-06-22 1995-03-07 Regents Of The University Of California Gene for ataxia-telangiectasia complementation group D (ATDC)
US5646008A (en) * 1993-06-22 1997-07-08 The Regent Of The University Of Michigan Vertebrate apoptosis gene: compositions and methods
JPH08511690A (ja) 1993-06-24 1996-12-10 ザ・ジェネラル・ホスピタル・コーポレーション プログラムされた細胞死遺伝子及びタンパク質
WO1995005738A1 (en) * 1993-08-20 1995-03-02 Massachusetts Institute Of Technology Anticancer agents and apoptosis
US5700638A (en) * 1993-08-26 1997-12-23 Washington University Cell death regulator
EP0731636B1 (de) * 1993-11-30 2006-01-11 Tanox, Inc. Cdn apoptosis modulierende proteine, sie kodierende dns und verfahren zu ihrer verwendung
US5672686A (en) * 1994-08-09 1997-09-30 Immunogen, Inc. Bcl-Y - specific antibodies
WO1996033416A1 (en) * 1995-04-20 1996-10-24 Lxr Biotechnology Inc. Methods of screening for therapeutic agents using novel apoptosis-modulating proteins
US5656725A (en) * 1995-05-12 1997-08-12 Apoptosis Technology, Inc. Peptides and compositions which modulate apoptosis
CA2427858A1 (en) * 2000-11-03 2002-05-10 University Of Vermont And State Agricultural College Compositions for inhibiting grb7

Also Published As

Publication number Publication date
HUT74276A (en) 1996-11-28
DE69434614T2 (de) 2006-10-05
AU1335195A (en) 1995-06-19
FI962247A0 (fi) 1996-05-29
NO962188D0 (no) 1996-05-29
US6015687A (en) 2000-01-18
CA2177827A1 (en) 1995-06-08
JPH09509567A (ja) 1997-09-30
EP0731636A4 (de) 1998-04-15
CN1139871A (zh) 1997-01-08
US7754418B2 (en) 2010-07-13
US6903195B1 (en) 2005-06-07
NO962188L (no) 1996-07-23
JP2006061159A (ja) 2006-03-09
JP2009189377A (ja) 2009-08-27
HU9601448D0 (en) 1996-07-29
US5770443A (en) 1998-06-23
US20030008837A1 (en) 2003-01-09
CA2177827C (en) 2007-08-28
FI962247A (fi) 1996-07-22
ATE315643T1 (de) 2006-02-15
US7108989B2 (en) 2006-09-19
WO1995015084A1 (en) 1995-06-08
EP0731636A1 (de) 1996-09-18
US20050164284A1 (en) 2005-07-28
US20070117748A1 (en) 2007-05-24
US6586395B1 (en) 2003-07-01
JP4129055B2 (ja) 2008-07-30
ES2256843T3 (es) 2006-07-16
JP2007252391A (ja) 2007-10-04
AU688839B2 (en) 1998-03-19
DE69434614D1 (de) 2006-04-06
EP0731636B1 (de) 2006-01-11

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