NZ261541A - Method of detecting autoantibodies to glutamic acid decarboxylase and its use in diagnosing a diabetic or prediabetic condition - Google Patents
Method of detecting autoantibodies to glutamic acid decarboxylase and its use in diagnosing a diabetic or prediabetic conditionInfo
- Publication number
- NZ261541A NZ261541A NZ261541A NZ26154194A NZ261541A NZ 261541 A NZ261541 A NZ 261541A NZ 261541 A NZ261541 A NZ 261541A NZ 26154194 A NZ26154194 A NZ 26154194A NZ 261541 A NZ261541 A NZ 261541A
- Authority
- NZ
- New Zealand
- Prior art keywords
- gad
- iddm
- antigen
- serum
- sera
- Prior art date
Links
- 108091022930 Glutamate decarboxylase Proteins 0.000 title claims abstract description 317
- 238000000034 method Methods 0.000 title claims abstract description 47
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Rehabilitation Therapy (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPL716893 | 1993-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ261541A true NZ261541A (en) | 1996-09-25 |
Family
ID=3776693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ261541A NZ261541A (en) | 1993-02-09 | 1994-02-09 | Method of detecting autoantibodies to glutamic acid decarboxylase and its use in diagnosing a diabetic or prediabetic condition |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5770381A (enExample) |
| EP (1) | EP0686262B1 (enExample) |
| JP (1) | JP3510889B2 (enExample) |
| AT (1) | ATE229650T1 (enExample) |
| CA (1) | CA2155677A1 (enExample) |
| DE (1) | DE69431874D1 (enExample) |
| IL (1) | IL108587A (enExample) |
| NZ (1) | NZ261541A (enExample) |
| SG (1) | SG45161A1 (enExample) |
| TW (1) | TW305936B (enExample) |
| WO (1) | WO1994018568A1 (enExample) |
| ZA (1) | ZA94845B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5821334A (en) * | 1996-01-26 | 1998-10-13 | Vanderbilt University | Insulin-dependent diabetes mellitus-specific chimeric polypeptides |
| FR2759701B1 (fr) * | 1997-02-19 | 1999-06-04 | Inst Nat Sante Rech Med | Utilisation des proteines ulip dans le diagnostic et la therapie des cancers et des syndromes neurologiques paraneoplasiques |
| AU3958999A (en) * | 1999-06-01 | 2000-12-18 | Kyokuto Pharmaceutical Industrial Co., Ltd. | Method for assaying anti-gad antibody and kit |
| ES2684976T3 (es) | 2012-04-13 | 2018-10-05 | Diabetomics, Inc. | Biomarcadores maternos para diabetes gestacional |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6682906B1 (en) * | 1990-09-21 | 2004-01-27 | The Regents Of The University Of California | Cloned glutamic acid decarboxylase |
| DE69233507T2 (de) * | 1991-02-22 | 2009-09-10 | The Walter And Eliza Hall Institute Of Medical Research, Parkville | Hbgad und higad polypeptide und nukleinsäuren und deren verwendung zur diagnose und behandlung von gad autoantigen assoziierten krankheiten |
| WO1992019972A1 (en) * | 1991-05-03 | 1992-11-12 | Novo Nordisk A/S | Islet cell autoantigen (gad) for the detection of preclinical diabetes |
-
1994
- 1994-02-08 TW TW083101065A patent/TW305936B/zh active
- 1994-02-08 ZA ZA94845A patent/ZA94845B/xx unknown
- 1994-02-08 IL IL108587A patent/IL108587A/en not_active IP Right Cessation
- 1994-02-09 WO PCT/AU1994/000056 patent/WO1994018568A1/en not_active Ceased
- 1994-02-09 US US08/495,584 patent/US5770381A/en not_active Expired - Fee Related
- 1994-02-09 EP EP94906796A patent/EP0686262B1/en not_active Expired - Lifetime
- 1994-02-09 CA CA002155677A patent/CA2155677A1/en not_active Abandoned
- 1994-02-09 JP JP51744894A patent/JP3510889B2/ja not_active Expired - Fee Related
- 1994-02-09 SG SG1996000807A patent/SG45161A1/en unknown
- 1994-02-09 AT AT94906796T patent/ATE229650T1/de not_active IP Right Cessation
- 1994-02-09 NZ NZ261541A patent/NZ261541A/en unknown
- 1994-02-09 DE DE69431874T patent/DE69431874D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP3510889B2 (ja) | 2004-03-29 |
| IL108587A (en) | 1998-01-04 |
| US5770381A (en) | 1998-06-23 |
| EP0686262A1 (en) | 1995-12-13 |
| TW305936B (enExample) | 1997-05-21 |
| WO1994018568A1 (en) | 1994-08-18 |
| IL108587A0 (en) | 1994-05-30 |
| SG45161A1 (en) | 1998-01-16 |
| ZA94845B (en) | 1994-11-11 |
| EP0686262B1 (en) | 2002-12-11 |
| EP0686262A4 (en) | 1997-06-04 |
| ATE229650T1 (de) | 2002-12-15 |
| JPH08506417A (ja) | 1996-07-09 |
| DE69431874D1 (de) | 2003-01-23 |
| CA2155677A1 (en) | 1994-08-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Rowley et al. | Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus | |
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| Hagopian et al. | Autoantibodies in IDDM Primarily Recognize the 65,000-M r Rather Than 67,000-M r Isoform of Glutamic Acid Decarboxylase | |
| Schlosser et al. | Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes | |
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| Timsit et al. | Islet cell antibody heterogeneity among type 1 (insulin-dependent) diabetic patients | |
| Teoh et al. | Autoantigenic reactivity of diabetes sera with a hybrid glutamic acid decarboxylase GAD67–65 molecule GAD67 (1–101)/GAD65 (96–585) | |
| Bassendine et al. | Primary biliary cirrhosis: nature of autoantigens | |
| Ziegler et al. | Autoantibodies to glutamate decarboxylase detected in diabetes-prone BB/OK rats do not distinguish onset of diabetes | |
| Rowley et al. | Diabetic sera react with the glutamic acid decarboxylase molecule in a dimeric‐oligomeric form | |
| McEvoy et al. | Anti-islet autoantibodies detected by monoclonal antibody 1A2: further studies suggesting a role in the pathogenesis of IDDM | |
| Gut et al. | Recombinant human thyroid peroxidase produced in insect cells has similar properties to native human thyroid peroxidase | |
| Ng et al. | Tyrosine phosphatase-like protein (IA-2) and glutamic acid decarboxylase (GAD65) autoantibodies: a study of Chinese patients with diabetes mellitus | |
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