NZ250580A - 3-(hetero)aryloxymorphinan derivatives and their use in the manufacture of medicaments - Google Patents
3-(hetero)aryloxymorphinan derivatives and their use in the manufacture of medicamentsInfo
- Publication number
- NZ250580A NZ250580A NZ250580A NZ25058093A NZ250580A NZ 250580 A NZ250580 A NZ 250580A NZ 250580 A NZ250580 A NZ 250580A NZ 25058093 A NZ25058093 A NZ 25058093A NZ 250580 A NZ250580 A NZ 250580A
- Authority
- NZ
- New Zealand
- Prior art keywords
- formula
- compound
- morphinan
- methyl
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US113593A | 1993-01-06 | 1993-01-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ250580A true NZ250580A (en) | 1996-07-26 |
Family
ID=21694554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ250580A NZ250580A (en) | 1993-01-06 | 1993-12-23 | 3-(hetero)aryloxymorphinan derivatives and their use in the manufacture of medicaments |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0612730B1 (enExample) |
| JP (1) | JP2501298B2 (enExample) |
| KR (1) | KR940018094A (enExample) |
| CN (1) | CN1097006A (enExample) |
| AT (1) | ATE154931T1 (enExample) |
| AU (1) | AU681601B2 (enExample) |
| BR (1) | BR9400021A (enExample) |
| CA (1) | CA2110337A1 (enExample) |
| CZ (1) | CZ2294A3 (enExample) |
| DE (1) | DE69311887T2 (enExample) |
| DK (1) | DK0612730T3 (enExample) |
| ES (1) | ES2105061T3 (enExample) |
| FI (1) | FI940041A7 (enExample) |
| GR (1) | GR3024891T3 (enExample) |
| HU (2) | HUT66061A (enExample) |
| IL (1) | IL108247A (enExample) |
| MX (1) | MX9400177A (enExample) |
| NO (1) | NO940028D0 (enExample) |
| NZ (1) | NZ250580A (enExample) |
| PL (1) | PL175365B1 (enExample) |
| TW (1) | TW264473B (enExample) |
| UY (1) | UY23706A1 (enExample) |
| ZA (1) | ZA939806B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9522176D0 (en) * | 1995-10-30 | 1996-01-03 | Iaf Biochem Int | Morphinan derivatives having neuroprotective activity |
| EP1384720A1 (en) * | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Process for drying paroxetine hydrochloride |
| FR2752163B1 (fr) * | 1996-08-12 | 1998-10-30 | Pf Medicament | Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington |
| GB9706753D0 (en) * | 1997-04-03 | 1997-05-21 | Pharmacia & Upjohn Spa | Aralkoxy-morphinan derivatives |
| KR100425881B1 (ko) * | 2001-03-14 | 2004-04-03 | 고광호 | 신규한 몰피난 유도체 |
| MXPA04011327A (es) * | 2002-05-17 | 2005-08-15 | Jenken Biosciences Inc | Opioides y compuestos similares a opioides y usos de los mismos. |
| DE10229842A1 (de) * | 2002-07-03 | 2004-02-05 | Helmut Prof. Dr. Schmidhammer | Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung |
| US20040204862A1 (en) | 2003-04-11 | 2004-10-14 | Wainer Irving W. | Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| CN102325776A (zh) * | 2009-02-23 | 2012-01-18 | 马林克罗特公司 | (+)-吗啡喃*季盐及其制备方法 |
| CN103044327B (zh) * | 2013-01-07 | 2014-12-17 | 苏州立新制药有限公司 | 一种右美沙芬的制备方法 |
| CN110664801A (zh) * | 2014-09-14 | 2020-01-10 | 阿瓦尼尔制药股份有限公司 | 用于治疗痴呆中的激越行为的包含右美沙芬化合物和奎尼丁的药物组合物 |
| US20160243112A1 (en) * | 2015-02-25 | 2016-08-25 | Alkermes, Inc. | Treatments for alzheimer's related diseases and disorders |
| KR20230044470A (ko) * | 2020-08-28 | 2023-04-04 | 닛뽕 케미파 가부시키가이샤 | 신규한 구리 촉매를 사용하여 디아릴 에테르 골격을 갖는 모르피난 유도체를 제조하는 방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4113729A (en) * | 1976-12-06 | 1978-09-12 | Hoffmann-La Roche Inc. | 3-Phenoxymorphinans and derivatives thereof |
| FI773636A7 (fi) * | 1976-12-06 | 1978-06-07 | Hoffmann La Roche | Nya fenylderivat |
| US4806543A (en) * | 1986-11-25 | 1989-02-21 | Board Of Trustees Of The Leland Stanford Junior University | Method and compositions for reducing neurotoxic injury |
-
1993
- 1993-11-25 TW TW082109942A patent/TW264473B/zh active
- 1993-11-30 CA CA002110337A patent/CA2110337A1/en not_active Abandoned
- 1993-12-20 DE DE69311887T patent/DE69311887T2/de not_active Expired - Fee Related
- 1993-12-20 ES ES93120498T patent/ES2105061T3/es not_active Expired - Lifetime
- 1993-12-20 DK DK93120498.6T patent/DK0612730T3/da active
- 1993-12-20 AT AT93120498T patent/ATE154931T1/de not_active IP Right Cessation
- 1993-12-20 EP EP93120498A patent/EP0612730B1/en not_active Expired - Lifetime
- 1993-12-23 NZ NZ250580A patent/NZ250580A/en unknown
- 1993-12-30 JP JP5354172A patent/JP2501298B2/ja not_active Expired - Lifetime
- 1993-12-30 ZA ZA939806A patent/ZA939806B/xx unknown
- 1993-12-31 AU AU52807/93A patent/AU681601B2/en not_active Ceased
- 1993-12-31 IL IL108247A patent/IL108247A/en not_active IP Right Cessation
- 1993-12-31 UY UY23706A patent/UY23706A1/es unknown
-
1994
- 1994-01-03 HU HU9400002A patent/HUT66061A/hu unknown
- 1994-01-03 MX MX9400177A patent/MX9400177A/es not_active IP Right Cessation
- 1994-01-04 KR KR1019940000067A patent/KR940018094A/ko not_active Ceased
- 1994-01-04 NO NO940028A patent/NO940028D0/no unknown
- 1994-01-05 FI FI940041A patent/FI940041A7/fi unknown
- 1994-01-05 PL PL94301784A patent/PL175365B1/pl unknown
- 1994-01-05 CZ CZ9422A patent/CZ2294A3/cs unknown
- 1994-01-05 BR BR9400021A patent/BR9400021A/pt not_active Application Discontinuation
- 1994-01-05 CN CN94100181A patent/CN1097006A/zh active Pending
-
1995
- 1995-06-19 HU HU95P/P00253P patent/HU211290A9/hu unknown
-
1997
- 1997-09-30 GR GR970402538T patent/GR3024891T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5280793A (en) | 1994-07-14 |
| EP0612730B1 (en) | 1997-07-02 |
| IL108247A0 (en) | 1994-04-12 |
| ZA939806B (en) | 1994-07-06 |
| JP2501298B2 (ja) | 1996-05-29 |
| HUT66061A (en) | 1994-09-28 |
| DE69311887D1 (de) | 1997-08-07 |
| UY23706A1 (es) | 1994-06-05 |
| PL175365B1 (pl) | 1998-12-31 |
| NO940028D0 (no) | 1994-01-04 |
| CZ2294A3 (en) | 1994-07-13 |
| AU681601B2 (en) | 1997-09-04 |
| ATE154931T1 (de) | 1997-07-15 |
| JPH06316564A (ja) | 1994-11-15 |
| TW264473B (enExample) | 1995-12-01 |
| ES2105061T3 (es) | 1997-10-16 |
| DE69311887T2 (de) | 1998-01-15 |
| KR940018094A (ko) | 1994-08-16 |
| BR9400021A (pt) | 1994-07-26 |
| FI940041A0 (fi) | 1994-01-05 |
| DK0612730T3 (da) | 1998-02-02 |
| FI940041L (fi) | 1994-07-07 |
| MX9400177A (es) | 1994-07-29 |
| CN1097006A (zh) | 1995-01-04 |
| IL108247A (en) | 1998-02-22 |
| HU9400002D0 (en) | 1994-05-30 |
| EP0612730A1 (en) | 1994-08-31 |
| GR3024891T3 (en) | 1998-01-30 |
| HU211290A9 (en) | 1995-11-28 |
| PL301784A1 (en) | 1994-07-11 |
| FI940041A7 (fi) | 1994-07-07 |
| CA2110337A1 (en) | 1994-07-07 |
| NO940028L (enExample) | 1994-07-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5308854A (en) | Inhibitors of HIV reverse transcriptase | |
| FI96768B (fi) | Menetelmä valmistaa farmakologisesti arvokasta bentso/5,6/sykloheptapyridiiniä | |
| US5574046A (en) | Heteroaryl amines as novel acetylcholinesterase inhibitors | |
| EP0612730B1 (en) | O-aryl ethers of morphinans | |
| US4879300A (en) | Novel piperidine derivatives | |
| JP2006522792A (ja) | ４−フェニル−ピペリジン化合物およびそのオピオイド受容体のモジュレーターとしての使用 | |
| US4806547A (en) | Isoquinoline derivatives, analgesic compounds thereof and method of treating pain | |
| JP3044055B2 (ja) | １，２―エタンジオール誘導体およびその塩 | |
| CS29991A2 (en) | Tricyclo-cyclic amines, method of their preparation and pharmaceutical preparations that them contain | |
| US5512575A (en) | Methanoanthraceneyl methyl piperidinyl compounds | |
| FR2557570A1 (fr) | Nouveaux derives de la quinoleine, leur procede de preparation et les compositions pharmaceutiques les renfermant | |
| US5180746A (en) | Aralkylamine compounds | |
| US5789425A (en) | Imidazolidinone derivatives, their acid adducts and therapeutic drugs for senile dementia | |
| EP2496579B1 (en) | 1-substituted 2-azabicyclo[3.1.1]heptyl derivatives useful as nicotinic acetylcholine receptor modulators for treating neurologic disorders | |
| US5438062A (en) | Benzo(5,6)cycloheptapyridines, compositions and methods of use | |
| US6057340A (en) | Oxazole derivatives as serotonin-1A receptor agonists | |
| IL93814A (en) | History of benzothiophyranilamines, their preparation and pharmaceutical preparations containing them | |
| EP0388977A2 (en) | Polycyclic amines useful as cerebrovascular agents | |
| EP0197318B1 (en) | Benzo[C]-1,5-naphthyridines, a process and intermediates for their preparation and their use as medicaments | |
| RU2123000C1 (ru) | О-арильные эфиры морфинанов, фармацевтическая композиция | |
| SK137597A3 (en) | 1-£'omega'-(3,4-dihydro-2-naphthalenyl)alkyl| cyclic amine derivatives, process for producing the same, and medicinal composition containing the same | |
| JPS63170356A (ja) | アニリン誘導体及びその製造法 | |
| JP3031634B2 (ja) | Ｄ１アンタゴニスト／ｄ２アンタゴニスト及び５ｈｔ２−セロトニンアンタゴニストとしてのピペリジニル置換メタノアントラセン | |
| HK1011351A1 (en) | Quinoline derivatives | |
| HK1011351B (en) | Quinoline derivatives |