NZ243972A - Beta-phenylisoserine derivatives and taxane derivatives prepared therefrom - Google Patents

Beta-phenylisoserine derivatives and taxane derivatives prepared therefrom

Info

Publication number
NZ243972A
NZ243972A NZ243972A NZ24397292A NZ243972A NZ 243972 A NZ243972 A NZ 243972A NZ 243972 A NZ243972 A NZ 243972A NZ 24397292 A NZ24397292 A NZ 24397292A NZ 243972 A NZ243972 A NZ 243972A
Authority
NZ
New Zealand
Prior art keywords
process according
phenyl
formula
mmol
mixture
Prior art date
Application number
NZ243972A
Other languages
English (en)
Inventor
Andrew Greene
Jean-Noel Denis
Alice Kanazawa
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NZ243972A publication Critical patent/NZ243972A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
NZ243972A 1991-08-19 1992-08-17 Beta-phenylisoserine derivatives and taxane derivatives prepared therefrom NZ243972A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR919110398A FR2680506B1 (fr) 1991-08-19 1991-08-19 Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.

Publications (1)

Publication Number Publication Date
NZ243972A true NZ243972A (en) 1994-11-25

Family

ID=9416254

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ243972A NZ243972A (en) 1991-08-19 1992-08-17 Beta-phenylisoserine derivatives and taxane derivatives prepared therefrom

Country Status (16)

Country Link
EP (2) EP0599973A1 (OSRAM)
JP (1) JPH06510033A (OSRAM)
AU (1) AU2490492A (OSRAM)
CA (1) CA2113827A1 (OSRAM)
CZ (1) CZ35494A3 (OSRAM)
FI (1) FI940775A0 (OSRAM)
FR (1) FR2680506B1 (OSRAM)
HU (1) HUT68255A (OSRAM)
MX (1) MX9204635A (OSRAM)
NO (1) NO940027L (OSRAM)
NZ (1) NZ243972A (OSRAM)
SK (1) SK19094A3 (OSRAM)
TW (1) TW222620B (OSRAM)
WO (1) WO1993004038A1 (OSRAM)
YU (1) YU78092A (OSRAM)
ZA (1) ZA926189B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3031715B2 (ja) * 1993-02-05 2000-04-10 ブリン モーアー カレッジ 様々なａ環側鎖を有するタキソール、類似体及び中間体の合成
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US5675025A (en) * 1995-06-07 1997-10-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6107497A (en) * 1996-02-29 2000-08-22 Napro Biotherapeutics, Inc. Intermediate for use in docetaxel synthesis and production method therefor
US5688977A (en) * 1996-02-29 1997-11-18 Napro Biotherapeutics, Inc. Method for docetaxel synthesis
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
US6452025B1 (en) 2001-04-25 2002-09-17 Napro Biotherapeutics, Inc. Three-step conversion of protected taxane ester to paclitaxel
DE60309847T2 (de) * 2002-02-27 2007-10-18 Ferring B.V. Zwischenprodukte und verfahren zur herstellung von heptapeptid-oxytocinanaloga
US9789193B2 (en) 2012-06-15 2017-10-17 The Brigham And Women's Hospital, Inc. Compositions for treating cancer and methods for making the same
WO2015153345A1 (en) 2014-04-03 2015-10-08 Invictus Oncology Pvt. Ltd. Supramolecular combinatorial therapeutics

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
US6455575B2 (en) 1992-12-24 2002-09-24 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives

Also Published As

Publication number Publication date
WO1993004038A1 (fr) 1993-03-04
CA2113827A1 (fr) 1993-03-04
EP0528729A1 (fr) 1993-02-24
JPH06510033A (ja) 1994-11-10
ZA926189B (en) 1993-03-01
FR2680506A1 (fr) 1993-02-26
TW222620B (OSRAM) 1994-04-21
EP0599973A1 (fr) 1994-06-08
SK19094A3 (en) 1994-09-07
CZ35494A3 (en) 1994-07-13
FI940775A7 (fi) 1994-02-18
AU2490492A (en) 1993-03-16
NO940027D0 (no) 1994-01-04
NO940027L (no) 1994-01-04
FI940775L (fi) 1994-02-18
YU78092A (sh) 1995-10-03
HUT68255A (en) 1995-06-28
MX9204635A (es) 1993-02-01
FR2680506B1 (fr) 1994-09-02
HU9400478D0 (en) 1994-06-28
FI940775A0 (fi) 1994-02-18

Similar Documents

Publication Publication Date Title
NZ243972A (en) Beta-phenylisoserine derivatives and taxane derivatives prepared therefrom
US6265587B1 (en) Intermediary compounds for the hemisynthesis of taxanes and preparation processes therefor
US5290957A (en) Process for the stereoselective preparation of phenylisoserine derivatives used in making taxols
IL98191A (en) Process for the enantioselective preparation of phenylisoserine derivatives
Quallich et al. Synthesis of 4 (S)-(3, 4-dichlorophenyl)-3, 4-dihydro-1 (2H)-naphthalenone by SN2 cuprate displacement of an activated chiral benzylic alcohol
EP0912495B1 (en) Asymetric synthesis of chiral beta-amino acids
Jones et al. Catalytic enantioselective synthesis of macrolides via asymmetric alkylation
Prempree et al. Reaction of methyl 4-bromocrotonate with lithium ester enolates: direct SN2 displacement vs. Michael-initiated ring closure
Osorio-Lozada et al. Synthesis and determination of the absolute stereochemistry of the enantiomers of adrafinil and modafinil
AU2018340858B2 (en) Chiral auxiliaries and uses thereof
Ter Wiel et al. Chiral overcrowded alkenes; Asymmetric synthesis of (3S, 3′ S)‐(M, M)‐(E)‐(+)‐1, 1′, 2, 2′, 3, 3′, 4, 4′‐octahydro‐3, 3′, 7, 7′‐tetramethyl‐4, 4′‐biphenanthrylidenes
Porter et al. Control of Dispersity and Stereochemistry in Free Radical Telomerizations: A Radical Addition, Cyclization, Chain Transfer (ACT) Strategy
Kita et al. First highly asymmetric Pummerer-type reaction in chiral, non-racemic acyclic sulfoxides induced by O-silylated ketene acetal
RU2109010C1 (ru) ПРОИЗВОДНОЕ β -ФЕНИЛИЗОСЕРИНА, СПОСОБ ЕГО СТЕРЕОСЕЛЕКТИВНОГО ПОЛУЧЕНИЯ, ИСХОДНОЕ СОЕДИНЕНИЕ ДЛЯ ЕГО ПОЛУЧЕНИЯ, СПОСОБ ПОЛУЧЕНИЯ ТАКСАНА И ПРОМЕЖУТОЧНЫЕ ПРОДУКТЫ
US20100317868A1 (en) Method of preparing taxane derivatives and intermediates used therein
Davies et al. Bifunctional chiral auxiliaries 8: Utilisation of tartaric acid derived auxiliaries in aldol and alkylation reactions
US20210054003A1 (en) Methods for the preparation of cyclopentaoxasilinones and cyclopentaoxaborininones and their use
AU754318B2 (en) Novel carboxylic acid derivatives and process for producing the same
US4183859A (en) Thenoylindan derivatives
US6559323B1 (en) Process for the preparation of an oxirane, aziridine or cyclopropane
AU772225B2 (en) Production method of optically active transvinylsulfide alcohol
EP2380871B1 (en) A process for the preparation of isoserine derivatives
PL178240B1 (pl) Nowe cis-N-iminometylo-beta-laktamy i sposób wytwarzania z nich pochodnych beta-laktamów
JPS6267066A (ja) ２−アルコキシベンゼンチオ−ル系化合物の製造方法
Osuga STUDIES ON SYNTHESIS OF OPTICALLY PURE HETEROHELICENES