NZ228168A - Piperidino or piperazino substituted purine derivatives and pharmaceutical compositions - Google Patents

Piperidino or piperazino substituted purine derivatives and pharmaceutical compositions

Info

Publication number
NZ228168A
NZ228168A NZ228168A NZ22816889A NZ228168A NZ 228168 A NZ228168 A NZ 228168A NZ 228168 A NZ228168 A NZ 228168A NZ 22816889 A NZ22816889 A NZ 22816889A NZ 228168 A NZ228168 A NZ 228168A
Authority
NZ
New Zealand
Prior art keywords
lower alkyl
compound
phenyl
halo
formula
Prior art date
Application number
NZ228168A
Other languages
English (en)
Inventor
Jeffrey B Press
Zoltan Hajos
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of NZ228168A publication Critical patent/NZ228168A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ228168A 1988-03-03 1989-02-28 Piperidino or piperazino substituted purine derivatives and pharmaceutical compositions NZ228168A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/163,488 US4885300A (en) 1988-03-03 1988-03-03 4-Substituted pyrazolo[3,4-D]pyrimidine derivatives

Publications (1)

Publication Number Publication Date
NZ228168A true NZ228168A (en) 1991-07-26

Family

ID=22590219

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ228168A NZ228168A (en) 1988-03-03 1989-02-28 Piperidino or piperazino substituted purine derivatives and pharmaceutical compositions

Country Status (15)

Country Link
US (3) US4885300A (no)
EP (1) EP0331510A3 (no)
JP (1) JP2567936B2 (no)
KR (1) KR940002827B1 (no)
CN (1) CN1030605C (no)
AU (1) AU612797B2 (no)
DK (1) DK101689A (no)
FI (1) FI92202C (no)
HU (1) HU204274B (no)
IL (1) IL89459A (no)
NO (1) NO169966C (no)
NZ (1) NZ228168A (no)
PH (1) PH25999A (no)
PT (1) PT89904B (no)
ZA (1) ZA891620B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3712735A1 (de) * 1987-04-15 1988-11-10 Boehringer Mannheim Gmbh Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel
EP0440515B1 (en) * 1990-01-30 1995-08-23 Visa International Service Association International authorization system
JP2651043B2 (ja) * 1990-07-10 1997-09-10 麒麟麦酒株式会社 ジフェニルメチルピペラジン誘導体
US5646152A (en) * 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
WO1998012171A1 (fr) * 1996-09-18 1998-03-26 Daiso Co., Ltd. Procede de preparation d'ethers 3-amino-2-hydroxy-1-propyliques
US6087512A (en) * 1996-09-18 2000-07-11 Daiso Co., Ltd. Process for preparation of glycidyl ether
CN106070266B (zh) * 2016-06-29 2018-11-30 贵州大学 吡唑[3,4-d]嘧啶酮席夫碱类化合物在制备抗植物病毒剂中的应用
CN110198932B (zh) * 2017-01-26 2023-04-07 东曹株式会社 烷醇胺、减摩剂、以及润滑油组合物
WO2018236745A1 (en) 2017-06-20 2018-12-27 Carnot, Llc COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF CARDIAC METABOLISM
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139705A (en) * 1977-05-20 1979-02-13 The Dow Chemical Company Pyrazolopyrimidines
FR2431710A1 (fr) * 1978-07-18 1980-02-15 Elf Aquitaine Procede d'exploration sismique par diagraphie acoustique
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4460303A (en) * 1982-07-29 1984-07-17 Ingersoll-Rand Company Drill pipe loader
US4603203A (en) * 1983-12-14 1986-07-29 Takeda Chemical Industries, Ltd. 3-aminopyrazolo[3,4-d]pyrimidine derivatives and production thereof
DE3423092A1 (de) * 1984-06-22 1986-01-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel
NL8700245A (nl) * 1986-02-14 1987-09-01 Sandoz Ag Purinederivaten, werkwijzen voor hun bereiding en geneesmiddelen die deze derivaten bevatten.
US4876257A (en) * 1988-03-03 1989-10-24 Ortho Pharmaceutical Corporation 6-Substituted purinyl piperazine derivatives useful as cardiotonic and antiarrhythmic agents

Also Published As

Publication number Publication date
HU204274B (en) 1991-12-30
HUT49353A (en) 1989-09-28
JPH01279890A (ja) 1989-11-10
US5001127A (en) 1991-03-19
NO890894L (no) 1989-09-04
ZA891620B (en) 1990-11-28
EP0331510A3 (en) 1991-03-13
AU3088389A (en) 1989-09-07
EP0331510A2 (en) 1989-09-06
NO169966C (no) 1992-08-26
IL89459A (en) 1993-04-04
AU612797B2 (en) 1991-07-18
NO890894D0 (no) 1989-03-02
KR890014542A (ko) 1989-10-24
FI891004A0 (fi) 1989-03-02
DK101689D0 (da) 1989-03-02
PT89904B (pt) 1994-11-30
US4885300A (en) 1989-12-05
FI891004A (fi) 1989-09-04
USRE35072E (en) 1995-10-24
IL89459A0 (en) 1989-09-10
PH25999A (en) 1992-01-13
PT89904A (pt) 1989-11-10
NO169966B (no) 1992-05-18
FI92202C (fi) 1994-10-10
KR940002827B1 (ko) 1994-04-04
JP2567936B2 (ja) 1996-12-25
DK101689A (da) 1989-09-04
CN1036766A (zh) 1989-11-01
CN1030605C (zh) 1996-01-03
FI92202B (fi) 1994-06-30

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