NZ208046A - Expression vector having a promoter/regulator region derived from yeast repressible acid phosphatase (ph05)gene and a structural gene coding for human leucocyte interferon - Google Patents

Expression vector having a promoter/regulator region derived from yeast repressible acid phosphatase (ph05)gene and a structural gene coding for human leucocyte interferon

Info

Publication number
NZ208046A
NZ208046A NZ208046A NZ20804684A NZ208046A NZ 208046 A NZ208046 A NZ 208046A NZ 208046 A NZ208046 A NZ 208046A NZ 20804684 A NZ20804684 A NZ 20804684A NZ 208046 A NZ208046 A NZ 208046A
Authority
NZ
New Zealand
Prior art keywords
interferon
expression vector
yeast
gene
promoter
Prior art date
Application number
NZ208046A
Other languages
English (en)
Inventor
R Kramer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ208046A publication Critical patent/NZ208046A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ208046A 1983-05-05 1984-05-03 Expression vector having a promoter/regulator region derived from yeast repressible acid phosphatase (ph05)gene and a structural gene coding for human leucocyte interferon NZ208046A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49167283A 1983-05-05 1983-05-05

Publications (1)

Publication Number Publication Date
NZ208046A true NZ208046A (en) 1988-04-29

Family

ID=23953166

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ208046A NZ208046A (en) 1983-05-05 1984-05-03 Expression vector having a promoter/regulator region derived from yeast repressible acid phosphatase (ph05)gene and a structural gene coding for human leucocyte interferon

Country Status (14)

Country Link
EP (1) EP0124874A3 (en, 2012)
JP (1) JPS60186288A (en, 2012)
AU (1) AU2767684A (en, 2012)
DK (1) DK224684A (en, 2012)
ES (2) ES532173A0 (en, 2012)
FI (1) FI841787A7 (en, 2012)
GR (1) GR79963B (en, 2012)
HU (1) HUT34239A (en, 2012)
IL (1) IL71745A0 (en, 2012)
MC (1) MC1598A1 (en, 2012)
NO (1) NO841811L (en, 2012)
NZ (1) NZ208046A (en, 2012)
PT (1) PT78552B (en, 2012)
ZA (1) ZA843275B (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0214638A3 (en) * 1985-09-09 1988-08-31 G.D. Searle & Co. Yeast promoters
JPH0655146B2 (ja) * 1985-12-27 1994-07-27 財団法人化学及血清療法研究所 シヤトルベクタ−
US5013652A (en) * 1986-10-14 1991-05-07 Genex Corporation Composite yeast vectors
DE3635867A1 (de) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
KR100374307B1 (ko) * 1995-07-21 2003-07-07 주식회사 엘지생명과학 재조합효모로부터발현된감마인터페론의정제방법
RU2203950C1 (ru) * 2002-01-15 2003-05-10 Общество с ограниченной ответственностью "Биотех" Штамм дрожжей pichia pastoris - продуцент лейкоцитарного интерферона-16 человека, рекомбинантная плазмидная днк phin и способ ее конструирования

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
IL72773A0 (en) * 1983-08-29 1984-11-30 Meloy Lab Production of immune interferon and its mrna

Also Published As

Publication number Publication date
FI841787L (fi) 1984-11-06
DK224684A (da) 1984-11-06
NO841811L (no) 1984-11-06
HUT34239A (en) 1985-02-28
GR79963B (en, 2012) 1984-10-31
ES8606887A1 (es) 1986-05-16
FI841787A7 (fi) 1984-11-06
FI841787A0 (fi) 1984-05-04
MC1598A1 (fr) 1985-05-09
ES8505411A1 (es) 1985-06-01
ZA843275B (en) 1984-12-24
EP0124874A3 (en) 1987-03-25
IL71745A0 (en) 1984-09-30
DK224684D0 (da) 1984-05-04
ES532173A0 (es) 1985-06-01
AU2767684A (en) 1984-11-08
PT78552B (en) 1986-09-15
JPS60186288A (ja) 1985-09-21
ES540038A0 (es) 1986-05-16
EP0124874A2 (en) 1984-11-14
PT78552A (en) 1984-06-01

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