NZ189625A - Amino sugar derivatives(trestatin a b and c) and amylase inhibiting compositions - Google Patents

Amino sugar derivatives(trestatin a b and c) and amylase inhibiting compositions

Info

Publication number
NZ189625A
NZ189625A NZ189625A NZ18962579A NZ189625A NZ 189625 A NZ189625 A NZ 189625A NZ 189625 A NZ189625 A NZ 189625A NZ 18962579 A NZ18962579 A NZ 18962579A NZ 189625 A NZ189625 A NZ 189625A
Authority
NZ
New Zealand
Prior art keywords
trestatin
sugar derivatives
amino sugar
inhibiting compositions
amylase inhibiting
Prior art date
Application number
NZ189625A
Other languages
English (en)
Inventor
K Watanabe
K Ogawa
Y Suhara
K Yokose
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ189625A publication Critical patent/NZ189625A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99Enzyme inactivation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NZ189625A 1978-02-14 1979-02-12 Amino sugar derivatives(trestatin a b and c) and amylase inhibiting compositions NZ189625A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB583478 1978-02-14

Publications (1)

Publication Number Publication Date
NZ189625A true NZ189625A (en) 1981-05-01

Family

ID=9803510

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ189625A NZ189625A (en) 1978-02-14 1979-02-12 Amino sugar derivatives(trestatin a b and c) and amylase inhibiting compositions

Country Status (26)

Country Link
US (1) US4273765A (esLanguage)
EP (1) EP0003616B1 (esLanguage)
JP (1) JPS54163511A (esLanguage)
AR (1) AR219150A1 (esLanguage)
AT (1) AT367451B (esLanguage)
AU (1) AU527318B2 (esLanguage)
CA (1) CA1121290A (esLanguage)
DE (2) DE2962165D1 (esLanguage)
DK (1) DK149599C (esLanguage)
ES (1) ES477653A1 (esLanguage)
FI (1) FI63062C (esLanguage)
FR (1) FR2416901A1 (esLanguage)
GR (1) GR72817B (esLanguage)
HU (1) HU181442B (esLanguage)
IE (1) IE47916B1 (esLanguage)
IL (1) IL56626A0 (esLanguage)
LU (1) LU80906A1 (esLanguage)
MC (1) MC1253A1 (esLanguage)
NL (1) NL7901182A (esLanguage)
NO (1) NO153011C (esLanguage)
NZ (1) NZ189625A (esLanguage)
PH (1) PH15084A (esLanguage)
PT (1) PT69218A (esLanguage)
SE (1) SE7901276L (esLanguage)
YU (1) YU41437B (esLanguage)
ZA (1) ZA79528B (esLanguage)

Families Citing this family (37)

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DE3166093D1 (en) 1981-01-05 1984-10-18 Takeda Chemical Industries Ltd N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) * 1981-03-09 1982-09-10 Akira Endo Hypoglycemic
US4595678A (en) * 1982-03-19 1986-06-17 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4885361A (en) * 1987-07-31 1989-12-05 Hoffmann-La Roche Inc. Sulfated oligosaccharides
EP0559795B1 (en) * 1990-11-30 1995-12-27 Monoclonetics International, Inc. Methods for the diagnosis of chronic lower back and cervical pain
CA2128044C (en) * 1993-08-05 2007-02-20 Klaus-Dieter Bremer Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
US7022684B2 (en) * 2000-05-24 2006-04-04 Pfizer Inc. Treatment of rumen acidosis with α-amylase inhibitors
IL143225A (en) * 2000-05-24 2008-03-20 Pfizer Preparation of drugs containing α-amylase inhibitors to treat hyperacidity of the inner abdomen
BRPI0416639A (pt) 2003-11-19 2007-01-16 Metabasis Therapeutics Inc tiromiméticos contendo fósforo
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
EP1819681B1 (en) * 2004-11-23 2009-08-12 Warner-Lambert Company LLC 7-(2h-pyrazol-3-yl)-3,5-dihydroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for the treatment of lipidemia
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP5115623B2 (ja) * 2008-04-11 2013-01-09 アステラス製薬株式会社 アミノ糖化合物及びその生産方法
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
CA2799708A1 (en) 2010-05-21 2011-11-24 Pfizer Inc. 2-phenyl benzoylamides
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US20130345392A1 (en) 2011-03-04 2013-12-26 Pfizer Inc Edn3-like peptides and uses thereof
US20150050371A1 (en) 2012-03-09 2015-02-19 Biotropics Malaysia Berhad Extract Formulations of Rhodamnia Cinerea And Uses Thereof
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same
US9708272B2 (en) 2014-08-29 2017-07-18 Tes Pharma S.R.L. Inhibitors of α-amino-β-carboxymuconic acid semialdehyde decarboxylase
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3526199B1 (en) 2016-10-14 2022-04-13 Tes Pharma S.r.l. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
MX2021005904A (es) 2018-11-20 2021-09-08 Tes Pharma S R L Inhibidores de la ácido alfa-amino-beta-carboximucónico semialdehído descarboxilasa.
AU2020209215B2 (en) 2019-01-18 2023-02-02 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) * 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
DE2347782C3 (de) * 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en) 1975-03-19 1979-02-06 American Cyanamid Company Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
ES477653A1 (es) 1980-03-01
JPS54163511A (en) 1979-12-26
ZA79528B (en) 1980-02-27
MC1253A1 (fr) 1980-01-14
GR72817B (esLanguage) 1983-12-06
EP0003616B1 (de) 1982-02-24
DE2962165D1 (en) 1982-03-25
YU41437B (en) 1987-06-30
DK61179A (da) 1979-08-15
YU34879A (en) 1983-01-21
CA1121290A (en) 1982-04-06
US4273765A (en) 1981-06-16
PT69218A (en) 1979-03-01
DE2905649A1 (de) 1979-08-16
AR219150A1 (es) 1980-07-31
FR2416901A1 (fr) 1979-09-07
EP0003616A3 (en) 1979-09-05
NL7901182A (nl) 1979-08-16
NO153011C (no) 1986-01-02
LU80906A1 (de) 1980-09-24
ATA108879A (de) 1981-11-15
IL56626A0 (en) 1979-05-31
IE47916B1 (en) 1984-07-25
FI63062B (fi) 1982-12-31
IE790274L (en) 1979-08-14
NO790469L (no) 1979-08-15
FR2416901B1 (esLanguage) 1980-10-24
PH15084A (en) 1982-07-02
DK149599C (da) 1987-06-01
JPS643877B2 (esLanguage) 1989-01-23
EP0003616A2 (de) 1979-08-22
FI790486A7 (fi) 1979-08-15
AU527318B2 (en) 1983-02-24
FI63062C (fi) 1983-04-11
NO153011B (no) 1985-09-23
AU4402879A (en) 1979-08-23
DK149599B (da) 1986-08-04
HU181442B (en) 1983-07-28
AT367451B (de) 1982-07-12
SE7901276L (sv) 1979-08-15

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