NZ188232A - Microspheres prepared at a temperature of minus 40 to minus 100 grad c - Google Patents

Microspheres prepared at a temperature of minus 40 to minus 100 grad c

Info

Publication number
NZ188232A
NZ188232A NZ188232A NZ18823278A NZ188232A NZ 188232 A NZ188232 A NZ 188232A NZ 188232 A NZ188232 A NZ 188232A NZ 18823278 A NZ18823278 A NZ 18823278A NZ 188232 A NZ188232 A NZ 188232A
Authority
NZ
New Zealand
Prior art keywords
minus
grad
temperature
microspheres prepared
microspheres
Prior art date
Application number
NZ188232A
Other languages
English (en)
Inventor
J W Fong
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of NZ188232A publication Critical patent/NZ188232A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28Microcapsules or nanocapsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • A61K8/025Explicitly spheroidal or spherical shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85Polyesters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00Formulations or additives for perfume preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/08Simple coacervation, i.e. addition of highly hydrophilic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60Particulates further characterized by their structure or composition
    • A61K2800/61Surface treated
    • A61K2800/62Coated
    • A61K2800/624Coated by macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60Particulates further characterized by their structure or composition
    • A61K2800/65Characterized by the composition of the particulate/core
    • A61K2800/654The particulate/core comprising macromolecular material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dentistry (AREA)
  • Dispersion Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
NZ188232A 1977-08-25 1978-08-23 Microspheres prepared at a temperature of minus 40 to minus 100 grad c NZ188232A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82771077A 1977-08-25 1977-08-25

Publications (1)

Publication Number Publication Date
NZ188232A true NZ188232A (en) 1980-12-19

Family

ID=25249947

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ188232A NZ188232A (en) 1977-08-25 1978-08-23 Microspheres prepared at a temperature of minus 40 to minus 100 grad c

Country Status (21)

Country Link
JP (1) JPS5455717A (fr)
AT (1) AT372019B (fr)
AU (1) AU522215B2 (fr)
BE (1) BE869915A (fr)
CA (1) CA1122077A (fr)
CH (2) CH649217A5 (fr)
DE (1) DE2836044A1 (fr)
DK (2) DK361878A (fr)
ES (1) ES472800A1 (fr)
FI (1) FI64899C (fr)
FR (1) FR2400950A1 (fr)
GB (1) GB2003108B (fr)
IE (1) IE47255B1 (fr)
IL (1) IL55418A (fr)
IT (1) IT1098111B (fr)
NL (1) NL7808613A (fr)
NZ (1) NZ188232A (fr)
PH (1) PH15447A (fr)
PT (1) PT68473A (fr)
SE (1) SE431942B (fr)
ZA (1) ZA784855B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045845B2 (ja) * 1979-10-31 1985-10-12 田辺製薬株式会社 医薬物質含有マイクロカプセルの製法
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
JPS5933214A (ja) * 1982-08-19 1984-02-23 Mitsui Toatsu Chem Inc 微小球に製剤された制ガン剤の製造方法
AT382076B (de) * 1982-10-15 1987-01-12 Chemie Linz Ag Verfahren zur herstellung von presslingen mit retardierter wirkstofffreisetzung
DE3417576A1 (de) * 1984-05-11 1985-11-14 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Retardformen des alpha-(2,5-dimethoxy-phenyl)-ss-glycinamidoaethanols und verfahren zu ihrer herstellung
DE3428372A1 (de) * 1984-08-01 1986-02-13 Hoechst Ag, 6230 Frankfurt Mikrokapseln von regulatorischen peptiden mit kontrollierter freisetzung, verfahren zu ihrer herstellung und injektionszubereitungen
CH660302A5 (fr) * 1984-10-17 1987-04-15 Debiopharm Sa Procede de micro-encapsulation en phase heterogene de substances medicamenteuses hydrosolubles.
CH669506A5 (en) * 1986-01-13 1989-03-31 Hugo Degen Oscillating and reclining furniture
DE3712095A1 (de) * 1987-04-10 1988-10-20 Lentia Gmbh Bindemittelfreies granulat mit verzoegerter wirkstoffabgabe
US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
FR2657255B1 (fr) * 1989-12-27 1992-04-24 Sederma Sa Description de preparations cosmetiques originales dont les principes actifs sont pieges dans un reseau polymerique greffe a la surface de particules de silice.
DE4127757A1 (de) * 1991-02-06 1992-08-13 Hoechst Ag Neue pflanzenschutzmittel-formulierungen
US6204308B1 (en) 1999-03-01 2001-03-20 Novartis Ag Organic compounds
EP1303387B1 (fr) 2000-05-12 2006-06-28 Matregen Corp. Procede permettant de produire des structures a l'aide de forces centrifuges
US6969480B2 (en) 2000-05-12 2005-11-29 Matregen Corp. Method of producing structures using centrifugal forces
US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
EP2219775A4 (fr) * 2007-12-11 2012-10-03 Univ Nanyang Tech Microsphères creuses multicouches pour l'administration de composés actifs hydrophiles
KR101294925B1 (ko) 2008-05-21 2013-08-08 도레이 카부시키가이샤 중합체 미립자의 제조 방법
CN103828801B (zh) * 2014-01-15 2016-01-27 福建农林大学 多杀菌素/甲氨基阿维菌素苯甲酸盐微球及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT631615A (fr) * 1960-02-26
US3427250A (en) * 1963-03-25 1969-02-11 Polaroid Corp Microscopic capsules and process for their preparation
US3531418A (en) * 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
FR1497584A (fr) * 1966-08-11 1967-10-13 Roussel Uclaf Procédé de fabrication de microcapsules
US3703474A (en) * 1967-08-21 1972-11-21 Ncr Co Encapsulation process
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
JPS51125675A (en) * 1975-02-13 1976-11-02 Asahi Chem Ind Co Ltd A porous capsule structvre and a process for manufacturing turing it

Also Published As

Publication number Publication date
AT372019B (de) 1983-08-25
IE781708L (en) 1979-02-25
IE47255B1 (en) 1984-02-08
DK618189A (da) 1989-12-07
FR2400950A1 (fr) 1979-03-23
FI64899C (fi) 1984-02-10
SE7808759L (sv) 1979-02-26
DK361878A (da) 1979-02-26
FI64899B (fi) 1983-10-31
CA1122077A (fr) 1982-04-20
SE431942B (sv) 1984-03-12
PT68473A (fr) 1978-09-01
FR2400950B1 (fr) 1983-10-07
IT7826961A0 (it) 1978-08-23
CH649217A5 (de) 1985-05-15
ATA612478A (de) 1983-01-15
AU522215B2 (en) 1982-05-20
AU3923678A (en) 1980-02-28
ES472800A1 (es) 1979-10-16
JPS5455717A (en) 1979-05-04
DE2836044A1 (de) 1979-03-01
PH15447A (en) 1983-01-18
ZA784855B (en) 1980-04-30
BE869915A (fr) 1979-02-23
NL7808613A (nl) 1979-02-27
CH644768A5 (de) 1984-08-31
IL55418A0 (en) 1978-10-31
DK618189D0 (da) 1989-12-07
FI782501A (fi) 1979-02-26
JPS645005B2 (fr) 1989-01-27
GB2003108B (en) 1982-03-24
IT1098111B (it) 1985-09-07
DE2836044C2 (fr) 1988-06-23
GB2003108A (en) 1979-03-07
IL55418A (en) 1981-07-31

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