NZ187813A - N'-(acyl or thioacyl)-n- (w-(indol-3-yl)alkyl) propane-1,3,-diamines and analogs therof - Google Patents

N'-(acyl or thioacyl)-n- (w-(indol-3-yl)alkyl) propane-1,3,-diamines and analogs therof

Info

Publication number
NZ187813A
NZ187813A NZ187813A NZ18781378A NZ187813A NZ 187813 A NZ187813 A NZ 187813A NZ 187813 A NZ187813 A NZ 187813A NZ 18781378 A NZ18781378 A NZ 18781378A NZ 187813 A NZ187813 A NZ 187813A
Authority
NZ
New Zealand
Prior art keywords
thioacyl
indol
diamines
acyl
propane
Prior art date
Application number
NZ187813A
Other languages
English (en)
Inventor
F Troxler
P Stadler
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of NZ187813A publication Critical patent/NZ187813A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ187813A 1977-07-12 1978-07-10 N'-(acyl or thioacyl)-n- (w-(indol-3-yl)alkyl) propane-1,3,-diamines and analogs therof NZ187813A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH858977 1977-07-12
CH300878 1978-03-20

Publications (1)

Publication Number Publication Date
NZ187813A true NZ187813A (en) 1981-03-16

Family

ID=25691930

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ187813A NZ187813A (en) 1977-07-12 1978-07-10 N'-(acyl or thioacyl)-n- (w-(indol-3-yl)alkyl) propane-1,3,-diamines and analogs therof

Country Status (14)

Country Link
EP (1) EP0000355B1 (es)
JP (1) JPS5436259A (es)
AU (1) AU521641B2 (es)
CA (1) CA1114381A (es)
DE (1) DE2861502D1 (es)
DK (1) DK300978A (es)
ES (1) ES471593A1 (es)
FI (1) FI782138A (es)
IE (1) IE47209B1 (es)
IL (1) IL55116A (es)
IT (1) IT7850140A0 (es)
NZ (1) NZ187813A (es)
PH (1) PH14993A (es)
PT (1) PT68270A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003901B1 (en) * 1978-02-24 1981-08-05 Pfizer Limited 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them
US4634713A (en) * 1982-05-28 1987-01-06 Ciba-Geigy Corporation Antihypertensive 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives
JPH0283380A (ja) * 1988-09-21 1990-03-23 Kotobuki Seiyaku Kk 新規ジアミン誘導体、抗不整脈剤及びその製法
FR2642422A1 (fr) * 1988-12-22 1990-08-03 Roussel Uclaf Nouvelles polyamines acylees, leur procede de preparation et leur application comme fongicides
DE69430861T2 (de) * 1993-04-07 2003-01-23 Otsuka Pharmaceutical Co., Ltd. N-acylierte 4-aminopiperidin derivate als aktive bestandteile von peripher gefässerweiternden wikstoffen
MY142362A (en) 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
US11764679B2 (en) 2020-01-15 2023-09-19 Solaredge Technologies Ltd. Power device
CN115433164B (zh) * 2022-09-14 2023-12-12 南京师范大学 烟酰胺衍生物及其制备方法和在抗衰老延长寿命中的应用

Also Published As

Publication number Publication date
AU3793978A (en) 1980-01-17
CA1114381A (en) 1981-12-15
EP0000355B1 (en) 1982-01-06
IE47209B1 (en) 1984-01-11
AU521641B2 (en) 1982-04-22
IL55116A0 (en) 1978-09-29
EP0000355A1 (en) 1979-01-24
DE2861502D1 (en) 1982-02-25
ES471593A1 (es) 1979-10-01
FI782138A (fi) 1979-01-13
IL55116A (en) 1982-02-28
IT7850140A0 (it) 1978-07-03
DK300978A (da) 1979-01-13
IE781382L (en) 1979-01-12
PH14993A (en) 1982-03-22
JPS5436259A (en) 1979-03-16
PT68270A (en) 1978-08-01

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