IL55116A - 3-(4-piperidyl-amino)-and 3-(amino-trimethyleneamino)-indole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-(4-piperidyl-amino)-and 3-(amino-trimethyleneamino)-indole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL55116A
IL55116A IL55116A IL5511678A IL55116A IL 55116 A IL55116 A IL 55116A IL 55116 A IL55116 A IL 55116A IL 5511678 A IL5511678 A IL 5511678A IL 55116 A IL55116 A IL 55116A
Authority
IL
Israel
Prior art keywords
amino
trimethyleneamino
piperidyl
preparation
pharmaceutical compositions
Prior art date
Application number
IL55116A
Other versions
IL55116A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL55116A0 publication Critical patent/IL55116A0/en
Publication of IL55116A publication Critical patent/IL55116A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL55116A 1977-07-12 1978-07-10 3-(4-piperidyl-amino)-and 3-(amino-trimethyleneamino)-indole derivatives,their preparation and pharmaceutical compositions containing them IL55116A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH858977 1977-07-12
CH300878 1978-03-20

Publications (2)

Publication Number Publication Date
IL55116A0 IL55116A0 (en) 1978-09-29
IL55116A true IL55116A (en) 1982-02-28

Family

ID=25691930

Family Applications (1)

Application Number Title Priority Date Filing Date
IL55116A IL55116A (en) 1977-07-12 1978-07-10 3-(4-piperidyl-amino)-and 3-(amino-trimethyleneamino)-indole derivatives,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0000355B1 (en)
JP (1) JPS5436259A (en)
AU (1) AU521641B2 (en)
CA (1) CA1114381A (en)
DE (1) DE2861502D1 (en)
DK (1) DK300978A (en)
ES (1) ES471593A1 (en)
FI (1) FI782138A (en)
IE (1) IE47209B1 (en)
IL (1) IL55116A (en)
IT (1) IT7850140A0 (en)
NZ (1) NZ187813A (en)
PH (1) PH14993A (en)
PT (1) PT68270A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003901B1 (en) * 1978-02-24 1981-08-05 Pfizer Limited 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them
US4634713A (en) * 1982-05-28 1987-01-06 Ciba-Geigy Corporation Antihypertensive 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives
JPH0283380A (en) * 1988-09-21 1990-03-23 Kotobuki Seiyaku Kk Novel diamine derivative, antiarrhythmic agent and production thereof
FR2642422A1 (en) * 1988-12-22 1990-08-03 Roussel Uclaf NOVEL ACYLATED POLYAMINES, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS FUNGICIDES
DE69430861T2 (en) * 1993-04-07 2003-01-23 Otsuka Pharmaceutical Co., Ltd. N-ACYLATED 4-AMINOPIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OF PERIPHERAL VESSEL WIDING AGENTS
MY142362A (en) 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
US11764679B2 (en) 2020-01-15 2023-09-19 Solaredge Technologies Ltd. Power device
CN115433164B (en) * 2022-09-14 2023-12-12 南京师范大学 Nicotinamide derivative, preparation method thereof and application thereof in resisting aging and prolonging life

Also Published As

Publication number Publication date
AU3793978A (en) 1980-01-17
CA1114381A (en) 1981-12-15
EP0000355B1 (en) 1982-01-06
NZ187813A (en) 1981-03-16
IE47209B1 (en) 1984-01-11
AU521641B2 (en) 1982-04-22
IL55116A0 (en) 1978-09-29
EP0000355A1 (en) 1979-01-24
DE2861502D1 (en) 1982-02-25
ES471593A1 (en) 1979-10-01
FI782138A (en) 1979-01-13
IT7850140A0 (en) 1978-07-03
DK300978A (en) 1979-01-13
IE781382L (en) 1979-01-12
PH14993A (en) 1982-03-22
JPS5436259A (en) 1979-03-16
PT68270A (en) 1978-08-01

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