DE2861502D1 - New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them. - Google Patents

New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them.

Info

Publication number
DE2861502D1
DE2861502D1 DE7878100274T DE2861502T DE2861502D1 DE 2861502 D1 DE2861502 D1 DE 2861502D1 DE 7878100274 T DE7878100274 T DE 7878100274T DE 2861502 T DE2861502 T DE 2861502T DE 2861502 D1 DE2861502 D1 DE 2861502D1
Authority
DE
Germany
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
indole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7878100274T
Other languages
German (de)
English (en)
Inventor
Paul Dr Stadler
Franz Dr Troxler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent GmbH
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of DE2861502D1 publication Critical patent/DE2861502D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE7878100274T 1977-07-12 1978-06-29 New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them. Expired DE2861502D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH858977 1977-07-12
CH300878 1978-03-20

Publications (1)

Publication Number Publication Date
DE2861502D1 true DE2861502D1 (en) 1982-02-25

Family

ID=25691930

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7878100274T Expired DE2861502D1 (en) 1977-07-12 1978-06-29 New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them.

Country Status (14)

Country Link
EP (1) EP0000355B1 (es)
JP (1) JPS5436259A (es)
AU (1) AU521641B2 (es)
CA (1) CA1114381A (es)
DE (1) DE2861502D1 (es)
DK (1) DK300978A (es)
ES (1) ES471593A1 (es)
FI (1) FI782138A (es)
IE (1) IE47209B1 (es)
IL (1) IL55116A (es)
IT (1) IT7850140A0 (es)
NZ (1) NZ187813A (es)
PH (1) PH14993A (es)
PT (1) PT68270A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003901B1 (en) * 1978-02-24 1981-08-05 Pfizer Limited 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them
US4634713A (en) * 1982-05-28 1987-01-06 Ciba-Geigy Corporation Antihypertensive 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives
JPH0283380A (ja) * 1988-09-21 1990-03-23 Kotobuki Seiyaku Kk 新規ジアミン誘導体、抗不整脈剤及びその製法
FR2642422A1 (fr) * 1988-12-22 1990-08-03 Roussel Uclaf Nouvelles polyamines acylees, leur procede de preparation et leur application comme fongicides
DE69430861T2 (de) * 1993-04-07 2003-01-23 Otsuka Pharmaceutical Co., Ltd. N-acylierte 4-aminopiperidin derivate als aktive bestandteile von peripher gefässerweiternden wikstoffen
MY142362A (en) 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
US11764679B2 (en) 2020-01-15 2023-09-19 Solaredge Technologies Ltd. Power device
CN115433164B (zh) * 2022-09-14 2023-12-12 南京师范大学 烟酰胺衍生物及其制备方法和在抗衰老延长寿命中的应用

Also Published As

Publication number Publication date
AU3793978A (en) 1980-01-17
CA1114381A (en) 1981-12-15
EP0000355B1 (en) 1982-01-06
NZ187813A (en) 1981-03-16
IE47209B1 (en) 1984-01-11
AU521641B2 (en) 1982-04-22
IL55116A0 (en) 1978-09-29
EP0000355A1 (en) 1979-01-24
ES471593A1 (es) 1979-10-01
FI782138A (fi) 1979-01-13
IL55116A (en) 1982-02-28
IT7850140A0 (it) 1978-07-03
DK300978A (da) 1979-01-13
IE781382L (en) 1979-01-12
PH14993A (en) 1982-03-22
JPS5436259A (en) 1979-03-16
PT68270A (en) 1978-08-01

Similar Documents

Publication Publication Date Title
DE2860900D1 (en) Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
IL54842A (en) 1-piperidino-phthalazine derivatives,their preparation and pharmaceutical compositions containing them
IL59524A0 (en) Indole derivatives,their preparation and pharmaceutical compositions containing them
DE2861317D1 (en) Cephalosporin derivatives, processes for their preparation and pharmaceutical compositions containing them
IL53996A (en) 1-substituted-2-fluoroalkylthio-4,5-diphenyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL56064A0 (en) Novel phenylglycine derivatives, their preparation and pharmaceutical compositions containing them
IL55109A0 (en) 1-acyl-2-cyanoaziridines,process for their preparation and pharmaceutical compositions containing them
IL55765A0 (en) New dihydtrophyridine derivatives,their preparation and pharmaceutical compositions containing them
DE2861361D1 (en) 1-n-acylated-4-o-glycosyl-6-o-glycosyl-1,3-diaminocyclitol derivatives, process for their preparation and pharmaceutical compositions containing them
IL54535A0 (en) Novel -lactam derivatives, their preparation and pharmaceutical compositions containing them
IL55170A (en) Indole derivatives,their production and pharmaceutical compositions containing them
IL53857A0 (en) New aminoalkoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
DE2861482D1 (en) Pyrazino-benzoxazepine and -benzthiazepine derivatives, processes for their production and pharmaceutical compositions containing them
IL55862A0 (en) Novel 6-oxygenated-3,20-dioxo-pregnane derivatives, process for the preparation thereof, and pharmaceutical compositionss containing them
DE2861502D1 (en) New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them.
IL55894A (en) 1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them
IL53766A0 (en) 4-diphenylmethylene-1-hydroxybenzyl-piperidine derivatives, their preparation and pharmaceutical compositions containing them
IL55857A (en) Benzodioxanylcarbonyl-piperazinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
ZA793682B (en) New piperidylbenzimidazolinone derivatives,processes for their preparation and pharmaceutical compositions containing them
DE2861767D1 (en) Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them
IL53861A0 (en) Novel n-aralkylaniline derivatives, their preparation and pharmaceutical compositions containing them
IL55120A0 (en) New 3-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL55095A0 (en) Novel piperidino-propanol derivatives,their preparation and pharmaceutical compositions containing them
IL55352A0 (en) New 3-amino-17a-aza-d-homoandrostane derivatives, their preparation and pharmaceutical compositions containing them
IL53948A0 (en) New thiazinoindole derivatives, their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SANDOZ-PATENT-GMBH, 7850 LOERRACH, DE

8339 Ceased/non-payment of the annual fee