NZ187377A - A-amino-a-substituted alkyl-a-fluoromethylacetic acids - Google Patents

A-amino-a-substituted alkyl-a-fluoromethylacetic acids

Info

Publication number
NZ187377A
NZ187377A NZ187377A NZ18737778A NZ187377A NZ 187377 A NZ187377 A NZ 187377A NZ 187377 A NZ187377 A NZ 187377A NZ 18737778 A NZ18737778 A NZ 18737778A NZ 187377 A NZ187377 A NZ 187377A
Authority
NZ
New Zealand
Prior art keywords
fluoromethylacetic
acids
amino
substituted alkyl
substituted
Prior art date
Application number
NZ187377A
Other languages
English (en)
Inventor
J Kollonitsch
S Marburg
A A Patchett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NZ187377A publication Critical patent/NZ187377A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
NZ187377A 1977-06-01 1978-05-25 A-amino-a-substituted alkyl-a-fluoromethylacetic acids NZ187377A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (1)

Publication Number Publication Date
NZ187377A true NZ187377A (en) 1981-05-15

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ187377A NZ187377A (en) 1977-06-01 1978-05-25 A-amino-a-substituted alkyl-a-fluoromethylacetic acids

Country Status (26)

Country Link
JP (1) JPS5416423A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR223463A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT360509B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU518479B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1120040A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH639639A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD138651A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2824116A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK149841C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES470296A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI66840C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2392958A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1602525A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR64495B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK18184A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU181911B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE46983B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1104709B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU79750A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL190485C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO147382C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ187377A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL115731B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT68102B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE7806440L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU129178A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
DK309479A (da) * 1978-07-24 1980-02-19 Merck & Co Inc Fremgangsmaade til fremstilling af alfadifluormethylaminosyrer og estere deraf
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
CA1158657A (en) * 1979-07-26 1983-12-13 Philippe Bey Preparation of fluorinated methyl aminoalkanoic acids and novel process intermediates
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
AU544990B2 (en) * 1980-06-16 1985-06-27 Merrell Pharmaceuticals Inc. Antiprotozal composition containing amino compounds
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
IT7849637A0 (it) 1978-05-31
JPS641474B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-01-11
NL190485C (nl) 1994-03-16
ATA393278A (de) 1980-06-15
NO147382C (no) 1983-03-30
NO147382B (no) 1982-12-20
SE7806440L (sv) 1978-12-02
PL115731B1 (en) 1981-04-30
FI66840C (fi) 1984-12-10
PL207242A1 (pl) 1979-04-23
FI66840B (fi) 1984-08-31
DK149841C (da) 1987-04-21
IE781078L (en) 1978-12-01
IT1104709B (it) 1985-10-28
DK149841B (da) 1986-10-13
CA1120040A (en) 1982-03-16
GR64495B (en) 1980-03-31
AU518479B2 (en) 1981-10-01
DE2824116C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-04-27
ES470296A1 (es) 1979-09-16
NO781892L (no) 1978-12-04
FR2392958B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-10-24
GB1602525A (en) 1981-11-11
LU79750A1 (fr) 1979-02-02
DE2824116A1 (de) 1978-12-14
DK237978A (da) 1979-01-19
PT68102A (en) 1978-06-01
CH639639A5 (en) 1983-11-30
NL190485B (nl) 1993-10-18
YU129178A (en) 1983-01-21
AR223463A1 (es) 1981-08-31
PT68102B (en) 1982-06-08
DD138651A5 (de) 1979-11-14
NL7805981A (nl) 1978-12-05
FI781674A7 (fi) 1978-12-02
FR2392958A1 (fr) 1978-12-29
JPS5416423A (en) 1979-02-07
HU181911B (en) 1983-11-28
AU3658678A (en) 1979-12-06
AT360509B (de) 1981-01-12
IE46983B1 (en) 1983-11-16
HK18184A (en) 1984-03-09

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