NO996244L - Pyrrolidinkarboksylsyrederivater som endotelinantagonister - Google Patents
Pyrrolidinkarboksylsyrederivater som endotelinantagonisterInfo
- Publication number
- NO996244L NO996244L NO996244A NO996244A NO996244L NO 996244 L NO996244 L NO 996244L NO 996244 A NO996244 A NO 996244A NO 996244 A NO996244 A NO 996244A NO 996244 L NO996244 L NO 996244L
- Authority
- NO
- Norway
- Prior art keywords
- acid derivatives
- pyrrolidinecarboxylic acid
- endothelin antagonists
- endothelin
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87718797A | 1997-06-17 | 1997-06-17 | |
PCT/US1998/011821 WO1998057933A1 (en) | 1997-06-17 | 1998-06-08 | Pyrrolidine carboxylic acid derivatives as endothelin antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
NO996244D0 NO996244D0 (no) | 1999-12-16 |
NO996244L true NO996244L (no) | 2000-01-12 |
Family
ID=25369437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO996244A NO996244L (no) | 1997-06-17 | 1999-12-16 | Pyrrolidinkarboksylsyrederivater som endotelinantagonister |
Country Status (8)
Country | Link |
---|---|
AR (1) | AR016071A1 (hu) |
AU (1) | AU7826398A (hu) |
BG (1) | BG103986A (hu) |
HU (1) | HUP0002681A3 (hu) |
NO (1) | NO996244L (hu) |
PL (1) | PL348667A1 (hu) |
WO (1) | WO1998057933A1 (hu) |
ZA (1) | ZA985209B (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7291626B1 (en) | 1998-04-09 | 2007-11-06 | John Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
CA2386190C (en) | 1999-10-13 | 2009-04-14 | Johns Hopkins University School Of Medicine | Regulators of the hedgehog pathway, compositions and uses related thereto |
US6552016B1 (en) | 1999-10-14 | 2003-04-22 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
ATE324876T1 (de) * | 1999-10-14 | 2006-06-15 | Curis Inc | VERMITTLER VON ßHEDGEHOGß ÜBERMITTELNDEN BAHNEN, DAZUGEHÖRIGE ZUSAMMENETZUNGEN UND VERWENDUNGEN |
AR044510A1 (es) * | 2003-04-14 | 2005-09-14 | Merck & Co Inc | Procedimiento e intermedios para preparar acidos carboxilicos de pirrolidina |
CN114507143A (zh) * | 2022-02-26 | 2022-05-17 | 江苏壹药新材料有限公司 | 一种2-乙基-1-氟-4-硝基苯的合成方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996006095A1 (en) * | 1994-08-19 | 1996-02-29 | Abbott Laboratories | Endothelin antagonists |
JP2000504727A (ja) * | 1996-02-13 | 2000-04-18 | アボット・ラボラトリーズ | エンドセリン拮抗物質としての4―(ベンゾ―1,3―ジオキソリル)―ピロリジン―3―カルボン酸誘導体 |
-
1998
- 1998-06-08 HU HU0002681A patent/HUP0002681A3/hu unknown
- 1998-06-08 PL PL98348667A patent/PL348667A1/xx unknown
- 1998-06-08 WO PCT/US1998/011821 patent/WO1998057933A1/en not_active Application Discontinuation
- 1998-06-08 AU AU78263/98A patent/AU7826398A/en not_active Abandoned
- 1998-06-15 ZA ZA985209A patent/ZA985209B/xx unknown
- 1998-06-16 AR ARP980102851A patent/AR016071A1/es unknown
-
1999
- 1999-12-10 BG BG103986A patent/BG103986A/xx unknown
- 1999-12-16 NO NO996244A patent/NO996244L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1998057933A1 (en) | 1998-12-23 |
AR016071A1 (es) | 2001-06-20 |
HUP0002681A3 (en) | 2001-09-28 |
HUP0002681A2 (hu) | 2001-08-28 |
ZA985209B (en) | 1999-01-06 |
PL348667A1 (en) | 2002-06-03 |
AU7826398A (en) | 1999-01-04 |
BG103986A (en) | 2000-08-31 |
NO996244D0 (no) | 1999-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |