NO996244L - Pyrrolidinkarboksylsyrederivater som endotelinantagonister - Google Patents

Pyrrolidinkarboksylsyrederivater som endotelinantagonister

Info

Publication number
NO996244L
NO996244L NO996244A NO996244A NO996244L NO 996244 L NO996244 L NO 996244L NO 996244 A NO996244 A NO 996244A NO 996244 A NO996244 A NO 996244A NO 996244 L NO996244 L NO 996244L
Authority
NO
Norway
Prior art keywords
acid derivatives
pyrrolidinecarboxylic acid
endothelin antagonists
endothelin
antagonists
Prior art date
Application number
NO996244A
Other languages
English (en)
Norwegian (no)
Other versions
NO996244D0 (no
Inventor
Andrew S Tasker
Martin Winn
Steven A Boyd
Hwan-Soo Jae
Thomas W Von Geldern
Bryan K Sorensen
Kenneth J Henry
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO996244D0 publication Critical patent/NO996244D0/no
Publication of NO996244L publication Critical patent/NO996244L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO996244A 1997-06-17 1999-12-16 Pyrrolidinkarboksylsyrederivater som endotelinantagonister NO996244L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87718797A 1997-06-17 1997-06-17
PCT/US1998/011821 WO1998057933A1 (en) 1997-06-17 1998-06-08 Pyrrolidine carboxylic acid derivatives as endothelin antagonists

Publications (2)

Publication Number Publication Date
NO996244D0 NO996244D0 (no) 1999-12-16
NO996244L true NO996244L (no) 2000-01-12

Family

ID=25369437

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996244A NO996244L (no) 1997-06-17 1999-12-16 Pyrrolidinkarboksylsyrederivater som endotelinantagonister

Country Status (8)

Country Link
AR (1) AR016071A1 (hu)
AU (1) AU7826398A (hu)
BG (1) BG103986A (hu)
HU (1) HUP0002681A3 (hu)
NO (1) NO996244L (hu)
PL (1) PL348667A1 (hu)
WO (1) WO1998057933A1 (hu)
ZA (1) ZA985209B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7291626B1 (en) 1998-04-09 2007-11-06 John Hopkins University School Of Medicine Inhibitors of hedgehog signaling pathways, compositions and uses related thereto
CA2386190C (en) 1999-10-13 2009-04-14 Johns Hopkins University School Of Medicine Regulators of the hedgehog pathway, compositions and uses related thereto
US6552016B1 (en) 1999-10-14 2003-04-22 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
ATE324876T1 (de) * 1999-10-14 2006-06-15 Curis Inc VERMITTLER VON ßHEDGEHOGß ÜBERMITTELNDEN BAHNEN, DAZUGEHÖRIGE ZUSAMMENETZUNGEN UND VERWENDUNGEN
AR044510A1 (es) * 2003-04-14 2005-09-14 Merck & Co Inc Procedimiento e intermedios para preparar acidos carboxilicos de pirrolidina
CN114507143A (zh) * 2022-02-26 2022-05-17 江苏壹药新材料有限公司 一种2-乙基-1-氟-4-硝基苯的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996006095A1 (en) * 1994-08-19 1996-02-29 Abbott Laboratories Endothelin antagonists
JP2000504727A (ja) * 1996-02-13 2000-04-18 アボット・ラボラトリーズ エンドセリン拮抗物質としての4―(ベンゾ―1,3―ジオキソリル)―ピロリジン―3―カルボン酸誘導体

Also Published As

Publication number Publication date
WO1998057933A1 (en) 1998-12-23
AR016071A1 (es) 2001-06-20
HUP0002681A3 (en) 2001-09-28
HUP0002681A2 (hu) 2001-08-28
ZA985209B (en) 1999-01-06
PL348667A1 (en) 2002-06-03
AU7826398A (en) 1999-01-04
BG103986A (en) 2000-08-31
NO996244D0 (no) 1999-12-16

Similar Documents

Publication Publication Date Title
CA2195677A1 (en) Endothelin antagonists
DK0894084T3 (da) Kanelsyrederivater og deres anvendelse som integrinantagonister
DE69705829D1 (de) Meta-substituierte phenylsulphonamidderivate
AU2337097A (en) Meta-substituted phenylene derivatives and their use as alphavbeta3 integrin antagonists or inhibitors
WO1999006397A3 (en) Pyrrolidine-3-carboxylic acid derivatives and their use as endothelin antagonists
DK0889875T3 (da) Cycloproylalkansyrederivater
ATE211732T1 (de) N-benzylpiperidin- und tetrahydropyridin-derivate
AU2536097A (en) Para-substituted phenylpropanoic acid derivatives as integrin antagonists
WO2003084936A8 (en) Amino substituted pyrimidinone derivatives useful in the treatment of inflammation and immunological
EP1609790A3 (en) Benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists
UY24625A1 (es) Derivados de la 4-hidroxi-piperidina
NO20001514L (no) Vitronectin-reseptor-antagonist
NO20001515L (no) Vitronektin reseptor-antagonist
IS3378A7 (is) 1,4 - Dihydropyridines, og aðferð við framleiðslu þess svo og notkun þess í lækningaskyni
TR199700206A2 (xx) Floralkil- ve floralkoksi ikame edilmi� heterosiklik bradikinin-antagonistleri, bunlar�n imal edilmesine mahsus usul ve bunlar�n kullan�lmalar�.
NO996244L (no) Pyrrolidinkarboksylsyrederivater som endotelinantagonister
EA199800701A1 (ru) БЕНЗО[С]ХИНОЛИЗИНОВЫЕ ПРОИЗВОДНЫЕ, ИХ ПОЛУЧЕНИЕ И ИСПОЛЬЗОВАНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ 5a-РЕДУКТАЗ
NO893525D0 (no) Amidoaminsalter av alkenylravsyrederivater, fremgangsmaater for deres fremstilling og deres anvendelse som korrosjonsinhibitorer.
AU2508584A (en) N-arylpiperazine derivatives
MX9701220A (es) Antagonistas de endotelina.
NO20004075L (no) Substituerte pyrimidin-2-yloksy-karboksylsyrederivater, fremstilling av disse og deres anvendelse som endotelin- antagonister
KR880001637A (ko) 치환된 이소퀴놀린 유도체, 그의 제조방법 및 그를 함유하는 항궤양제
HUP0002727A2 (hu) Eljárás fibrinogén csökkentésére benzotiofénszármazékok felhasználásával
NO20012328D0 (no) Fluorerte 3,4-dihydrokinolinderivater anvendt som NOS- inhibitorer
IT8520908A0 (it) Sali doppi di derivati dell'acido desossicolico, loro impiego eprocedimento per la loro preparazione.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application