BG103986A - Derivatives of pyrrolidinecarboxylic acids as endotheline antagonists - Google Patents
Derivatives of pyrrolidinecarboxylic acids as endotheline antagonistsInfo
- Publication number
- BG103986A BG103986A BG103986A BG10398699A BG103986A BG 103986 A BG103986 A BG 103986A BG 103986 A BG103986 A BG 103986A BG 10398699 A BG10398699 A BG 10398699A BG 103986 A BG103986 A BG 103986A
- Authority
- BG
- Bulgaria
- Prior art keywords
- derivatives
- endotheline
- endotheline antagonists
- pyrrolidinecarboxylic acids
- pyrrolidinecarboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87718797A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011821 WO1998057933A1 (en) | 1997-06-17 | 1998-06-08 | Pyrrolidine carboxylic acid derivatives as endothelin antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG103986A true BG103986A (en) | 2000-08-31 |
Family
ID=25369437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103986A BG103986A (en) | 1997-06-17 | 1999-12-10 | Derivatives of pyrrolidinecarboxylic acids as endotheline antagonists |
Country Status (8)
| Country | Link |
|---|---|
| AR (1) | AR016071A1 (hu) |
| AU (1) | AU7826398A (hu) |
| BG (1) | BG103986A (hu) |
| HU (1) | HUP0002681A3 (hu) |
| NO (1) | NO996244L (hu) |
| PL (1) | PL348667A1 (hu) |
| WO (1) | WO1998057933A1 (hu) |
| ZA (1) | ZA985209B (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7291626B1 (en) | 1998-04-09 | 2007-11-06 | John Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
| EP1728797A3 (en) | 1999-10-13 | 2011-03-02 | Johns Hopkins University School of Medicine | Regulators of the hedgehog pathway, compositions and uses related thereto |
| US6552016B1 (en) | 1999-10-14 | 2003-04-22 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| EP1227805B2 (en) * | 1999-10-14 | 2011-02-23 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| AR044510A1 (es) * | 2003-04-14 | 2005-09-14 | Merck & Co Inc | Procedimiento e intermedios para preparar acidos carboxilicos de pirrolidina |
| CN114507143A (zh) * | 2022-02-26 | 2022-05-17 | 江苏壹药新材料有限公司 | 一种2-乙基-1-氟-4-硝基苯的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2517691A1 (en) * | 1994-08-19 | 1996-02-29 | Abbott Laboratories | Endothelin antagonists |
| BR9707394A (pt) * | 1996-02-13 | 1999-04-06 | Abbott Lab | Derivados de ácido 4-(benzo-1,3-dioxolil) pirrolidino-3-carboxílico como antagonistas endotelina |
-
1998
- 1998-06-08 HU HU0002681A patent/HUP0002681A3/hu unknown
- 1998-06-08 AU AU78263/98A patent/AU7826398A/en not_active Abandoned
- 1998-06-08 WO PCT/US1998/011821 patent/WO1998057933A1/en not_active Application Discontinuation
- 1998-06-08 PL PL98348667A patent/PL348667A1/xx unknown
- 1998-06-15 ZA ZA985209A patent/ZA985209B/xx unknown
- 1998-06-16 AR ARP980102851A patent/AR016071A1/es unknown
-
1999
- 1999-12-10 BG BG103986A patent/BG103986A/xx unknown
- 1999-12-16 NO NO996244A patent/NO996244L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO996244L (no) | 2000-01-12 |
| PL348667A1 (en) | 2002-06-03 |
| HUP0002681A2 (hu) | 2001-08-28 |
| AR016071A1 (es) | 2001-06-20 |
| ZA985209B (en) | 1999-01-06 |
| NO996244D0 (no) | 1999-12-16 |
| AU7826398A (en) | 1999-01-04 |
| HUP0002681A3 (en) | 2001-09-28 |
| WO1998057933A1 (en) | 1998-12-23 |
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