NO995808D0 - Forbindelser, deres fremstilling og anvendelse for overföring av nukleinsyrer inn i celler - Google Patents

Forbindelser, deres fremstilling og anvendelse for overföring av nukleinsyrer inn i celler

Info

Publication number
NO995808D0
NO995808D0 NO995808A NO995808A NO995808D0 NO 995808 D0 NO995808 D0 NO 995808D0 NO 995808 A NO995808 A NO 995808A NO 995808 A NO995808 A NO 995808A NO 995808 D0 NO995808 D0 NO 995808D0
Authority
NO
Norway
Prior art keywords
compounds
nucleic acids
cells
transfer
preparation
Prior art date
Application number
NO995808A
Other languages
English (en)
Other versions
NO314497B1 (no
NO995808L (no
Inventor
Gerardo Byk
Cathrine Dubertret
Daniel Scherman
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO995808D0 publication Critical patent/NO995808D0/no
Publication of NO995808L publication Critical patent/NO995808L/no
Publication of NO314497B1 publication Critical patent/NO314497B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO19995808A 1997-05-28 1999-11-26 Lipopolyamin i D-, L- eller DL-form, deres fremstilling og anvendelse samtpreparater inneholdende forbindelsene NO314497B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9706549A FR2763943B1 (fr) 1997-05-28 1997-05-28 Composes, leur preparation et leur utilisation pour le transfert d'acides nucleiques dans les cellules
PCT/FR1998/001041 WO1998054130A1 (fr) 1997-05-28 1998-05-25 Composes, leur preparation et leur utilisation pour le transfert d'acides nucleiques dans les cellules

Publications (3)

Publication Number Publication Date
NO995808D0 true NO995808D0 (no) 1999-11-26
NO995808L NO995808L (no) 1999-11-26
NO314497B1 NO314497B1 (no) 2003-03-31

Family

ID=9507333

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19995808A NO314497B1 (no) 1997-05-28 1999-11-26 Lipopolyamin i D-, L- eller DL-form, deres fremstilling og anvendelse samtpreparater inneholdende forbindelsene

Country Status (17)

Country Link
US (1) US6300321B1 (no)
EP (1) EP0984925B1 (no)
JP (1) JP4467084B2 (no)
KR (1) KR20010013029A (no)
CN (1) CN1131208C (no)
AT (1) ATE284383T1 (no)
AU (1) AU738320B2 (no)
BR (1) BR9809506A (no)
CA (1) CA2290664C (no)
DE (1) DE69828045T2 (no)
FR (1) FR2763943B1 (no)
HU (1) HUP0001937A3 (no)
IL (1) IL132951A0 (no)
NO (1) NO314497B1 (no)
PL (1) PL336983A1 (no)
WO (1) WO1998054130A1 (no)
ZA (1) ZA984440B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7960540B2 (en) 1999-04-08 2011-06-14 Advanced Cancer Therapeutics, Llc Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin
US8114850B2 (en) 1999-04-08 2012-02-14 Advanced Cancer Therapeutics, Llc Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin
JP2002541264A (ja) 1999-04-08 2002-12-03 ユーエイビー・リサーチ・ファウンデーション 冨ｇオリゴヌクレオチドの抗増殖活性およびヌクレオリンに結合するためのその使用方法
US20020091242A1 (en) 2000-10-11 2002-07-11 Michel Bessodes Acid-sensitive compounds, their preparation and uses
CA2429803A1 (en) * 2000-11-29 2002-06-06 Gencell S.A. Neutral and anionic colloidal particles for gene delivery
US20030134423A1 (en) * 2002-01-04 2003-07-17 Chu Yong Liang Compounds for delivering substances into cells
JP2005529959A (ja) * 2002-06-14 2005-10-06 マイラス コーポレイション 細胞へのポリヌクレオチドの伝達をするための新規な方法
EP1638610B1 (en) * 2003-06-18 2015-03-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Sphingoid polyalkylamine conjugates for vaccination
US7906122B2 (en) * 2003-06-18 2011-03-15 Yissum Research Development Company Of The Hebrew University Of Jersusalem Sphingoid polyalkylamine conjugates for Hepatitis B virus vaccination
GB0413613D0 (en) * 2004-06-17 2004-07-21 Univ London Small molecule carriers
KR100699279B1 (ko) 2005-04-28 2007-03-23 학교법인 포항공과대학교 당 또는 당 유사체를 골격으로 하는 분자 수송체 및 그의제조방법
US7973084B2 (en) 2005-04-28 2011-07-05 Postech Academy-Industrial Foundation Molecular transporters based on alditol or inositol and processes for the preparation thereof
US20070208082A1 (en) * 2005-08-10 2007-09-06 John Hopkins University Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
GB0613753D0 (en) * 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
HUE21212055T1 (hu) 2011-12-07 2022-11-28 Alnylam Pharmaceuticals Inc Biológiailag lebontható lipidek hatóanyagok bejuttatására
CA2953341C (en) 2014-06-25 2023-01-24 Acuitas Therapeutics Inc. Lipids and lipid nanoparticle formulations for delivery of nucleic acids
FI3313829T3 (fi) 2015-06-29 2024-07-01 Acuitas Therapeutics Inc Lipidejä ja lipidinanohiukkasformulaatioita nukleiinihappojen annostelemiseksi
HUE061564T2 (hu) 2015-10-28 2023-07-28 Acuitas Therapeutics Inc Új lipidek és lipid nanorészecske készítmények nukleinsavak bevitelére
WO2018191657A1 (en) 2017-04-13 2018-10-18 Acuitas Therapeutics, Inc. Lipids for delivery of active agents
AU2018256877B2 (en) 2017-04-28 2022-06-02 Acuitas Therapeutics, Inc. Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids
JP7355731B2 (ja) 2017-08-16 2023-10-03 アクイタス セラピューティクス インコーポレイテッド 脂質ナノ粒子製剤における使用のための脂質
WO2019036030A1 (en) 2017-08-17 2019-02-21 Acuitas Therapeutics, Inc. LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS
US12065396B2 (en) 2017-08-17 2024-08-20 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
US11542225B2 (en) 2017-08-17 2023-01-03 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
FI3908568T3 (fi) 2019-01-11 2024-09-13 Acuitas Therapeutics Inc Lipidit aktiivisten aineiden lipidinanohiukkastoimitusta varten
EP4182297A1 (en) 2020-07-16 2023-05-24 Acuitas Therapeutics, Inc. Cationic lipids for use in lipid nanoparticles
IL313486A (en) 2021-12-16 2024-08-01 Acuitas Therapeutics Inc Lipids for use in lipid nanoparticle formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960705771A (ko) * 1993-11-24 1996-11-08 벤자민 에프 맥그로우 구아니딘의 양쪽친화성 유도체(amphiphilic derivatives of guanidine)
US5777153A (en) * 1994-07-08 1998-07-07 Gilead Sciences, Inc. Cationic lipids
FR2727679B1 (fr) * 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
FR2730637B1 (fr) * 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
FR2741066B1 (fr) * 1995-11-14 1997-12-12 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
IL125926A (en) * 1996-03-01 2004-09-27 Centre Nat Rech Scient Compounds related to the amidinium family, pharmaceutical preparations containing them and their uses

Also Published As

Publication number Publication date
KR20010013029A (ko) 2001-02-26
PL336983A1 (en) 2000-07-31
DE69828045D1 (de) 2005-01-13
NO314497B1 (no) 2003-03-31
WO1998054130A1 (fr) 1998-12-03
JP4467084B2 (ja) 2010-05-26
IL132951A0 (en) 2001-03-19
BR9809506A (pt) 2000-06-20
EP0984925B1 (fr) 2004-12-08
ZA984440B (en) 1998-12-10
CN1257480A (zh) 2000-06-21
HUP0001937A3 (en) 2003-10-28
FR2763943B1 (fr) 1999-07-09
CA2290664A1 (fr) 1998-12-03
CN1131208C (zh) 2003-12-17
AU738320B2 (en) 2001-09-13
CA2290664C (fr) 2010-04-13
HUP0001937A2 (hu) 2000-10-28
US6300321B1 (en) 2001-10-09
JP2002502388A (ja) 2002-01-22
AU8022198A (en) 1998-12-30
ATE284383T1 (de) 2004-12-15
FR2763943A1 (fr) 1998-12-04
DE69828045T2 (de) 2005-12-01
EP0984925A1 (fr) 2000-03-15
NO995808L (no) 1999-11-26

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