NO992875L - Fremstilling av enantiomert anriket threo-metylfenidat - Google Patents

Fremstilling av enantiomert anriket threo-metylfenidat

Info

Publication number
NO992875L
NO992875L NO992875A NO992875A NO992875L NO 992875 L NO992875 L NO 992875L NO 992875 A NO992875 A NO 992875A NO 992875 A NO992875 A NO 992875A NO 992875 L NO992875 L NO 992875L
Authority
NO
Norway
Prior art keywords
methylphenidate
preparation
enantiomerically enriched
threo
enriched threo
Prior art date
Application number
NO992875A
Other languages
English (en)
Norwegian (no)
Other versions
NO992875D0 (no
Inventor
Susan Faulconbridge
Hooshang Shahriari Zavareh
Graham Robert Evans
Marianne Langston
Original Assignee
Medeva Europ Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625972.6A external-priority patent/GB9625972D0/en
Priority claimed from GBGB9712298.0A external-priority patent/GB9712298D0/en
Application filed by Medeva Europ Ltd filed Critical Medeva Europ Ltd
Publication of NO992875D0 publication Critical patent/NO992875D0/no
Publication of NO992875L publication Critical patent/NO992875L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO992875A 1996-12-13 1999-06-11 Fremstilling av enantiomert anriket threo-metylfenidat NO992875L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9625972.6A GB9625972D0 (en) 1996-12-13 1996-12-13 Bioresolution
GBGB9712298.0A GB9712298D0 (en) 1997-06-12 1997-06-12 Crystallisation
PCT/GB1997/003418 WO1998025902A1 (en) 1996-12-13 1997-12-11 The preparation of enantiomerically-enriched threo-methylphenidate

Publications (2)

Publication Number Publication Date
NO992875D0 NO992875D0 (no) 1999-06-11
NO992875L true NO992875L (no) 1999-06-14

Family

ID=26310627

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992875A NO992875L (no) 1996-12-13 1999-06-11 Fremstilling av enantiomert anriket threo-metylfenidat

Country Status (9)

Country Link
EP (1) EP0948484A1 (hu)
JP (1) JP2001506621A (hu)
AU (1) AU7847098A (hu)
CA (1) CA2272373A1 (hu)
CZ (1) CZ206299A3 (hu)
HU (1) HUP0001604A3 (hu)
NO (1) NO992875L (hu)
PL (1) PL334136A1 (hu)
WO (1) WO1998025902A1 (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486177B2 (en) 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US6100401A (en) * 1998-04-20 2000-08-08 Novartris Ag Process for preparing the d-threo isomer of methylphenidate hydrochloride
US6162919A (en) * 1998-12-03 2000-12-19 Novartis Ag Process for preparing the d-threo isomer of methylphenidate hydrochloride
US6395752B1 (en) * 1999-03-04 2002-05-28 Pharmaquest Limited Method of treating depression using 1-threo-methylphenidate
US6127385A (en) * 1999-03-04 2000-10-03 Pharmaquest Limited Method of treating depression using l-threo-methylphenidate
US6025502A (en) * 1999-03-19 2000-02-15 The Trustees Of The University Of Pennsylvania Enantopselective synthesis of methyl phenidate
US6221883B1 (en) * 2000-04-12 2001-04-24 Ross Baldessarini Method of dopamine inhibition using l-threo-methylphenidate
DE60027282T2 (de) * 2000-06-17 2007-04-12 Pharmaquest Ltd., Hamilton Verwendung von l-threo-methylphenidate zur Herstellung eines Medikaments für die Behandlung von Depression
US7247730B2 (en) * 2003-03-07 2007-07-24 Isp Investments Inc. Process for the preparation of dexmethylphenidate hydrochloride
US7897777B2 (en) 2007-01-05 2011-03-01 Archimica, Inc. Process of enantiomeric resolution of D,L-(±)-threo-methylphenidate
US8552030B2 (en) 2009-05-07 2013-10-08 Malladi Drugs & Pharmaceuticals Ltd. Process for the preparation of d-threo-ritalinic acid hydrochloride by resolution of dl-threo-ritalinic acid using chiral carboxylic acid
CN103298785B (zh) 2010-12-17 2016-04-20 罗德科技公司 盐酸哌醋甲酯的低温合成
US9498447B2 (en) 2011-03-23 2016-11-22 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US9283214B2 (en) 2011-03-23 2016-03-15 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US9119809B2 (en) 2011-03-23 2015-09-01 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US9603809B2 (en) 2011-03-23 2017-03-28 Ironshore Pharmaceuticals & Development, Inc. Methods of treatment of attention deficit hyperactivity disorder
US10905652B2 (en) 2011-03-23 2021-02-02 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US8916588B2 (en) 2011-03-23 2014-12-23 Ironshore Pharmaceuticals & Development, Inc. Methods for treatment of attention deficit hyperactivity disorder
US8927010B2 (en) 2011-03-23 2015-01-06 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US10292937B2 (en) 2011-03-23 2019-05-21 Ironshore Pharmaceuticals & Development, Inc. Methods of treatment of attention deficit hyperactivity disorder
US11241391B2 (en) 2011-03-23 2022-02-08 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
DK2688557T3 (da) 2011-03-23 2017-11-27 Ironshore Pharmaceuticals & Dev Inc Fremgangsmåder og sammensætninger til behandling af forstyrelse af opmærksomhed
US9233924B2 (en) 2014-03-11 2016-01-12 Ampac Fine Chemicals Llc Methods for preparing D-threo methylphenidate using diazomethane, and compositions thereof
EP3160937B1 (en) 2014-06-27 2020-12-30 Embio Limited A novel method for synthesis of optically pure beta-amino alcohols

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02190195A (ja) * 1989-01-19 1990-07-26 Rikagaku Kenkyusho 光学活性プロピオン酸エステル類化合物の製法
JPH02273196A (ja) * 1989-03-08 1990-11-07 Wisconsin Alumni Res Found ラセミ化合物の生体触媒分割のエナンチオ選択性の改良法
JP3431204B2 (ja) * 1993-04-22 2003-07-28 塩野義製薬株式会社 ノルボルナン型エステル・ヒドロラーゼ
BE1007297A3 (nl) * 1993-07-19 1995-05-09 Dsm Nv Werkwijze voor de bereiding van optisch aktieve alcoholen en esters, en alcoholen en esters toegepast en bereid in dergelijke werkwijzen.
DE4420751A1 (de) * 1994-06-15 1995-12-21 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Lactamen

Also Published As

Publication number Publication date
PL334136A1 (en) 2000-02-14
EP0948484A1 (en) 1999-10-13
WO1998025902A1 (en) 1998-06-18
AU7847098A (en) 1998-07-03
HUP0001604A3 (en) 2003-03-28
CZ206299A3 (cs) 1999-09-15
JP2001506621A (ja) 2001-05-22
HUP0001604A2 (hu) 2000-10-28
NO992875D0 (no) 1999-06-11
CA2272373A1 (en) 1998-06-18

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