AU7847098A - The preparation of enantiomerically-enriched threo- methylphenidate - Google Patents
The preparation of enantiomerically-enriched threo- methylphenidateInfo
- Publication number
- AU7847098A AU7847098A AU78470/98A AU7847098A AU7847098A AU 7847098 A AU7847098 A AU 7847098A AU 78470/98 A AU78470/98 A AU 78470/98A AU 7847098 A AU7847098 A AU 7847098A AU 7847098 A AU7847098 A AU 7847098A
- Authority
- AU
- Australia
- Prior art keywords
- methylphenidate
- enantiomerically
- preparation
- threo
- enriched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9625972.6A GB9625972D0 (en) | 1996-12-13 | 1996-12-13 | Bioresolution |
| GB9625972 | 1996-12-13 | ||
| GB9712298 | 1997-06-12 | ||
| GBGB9712298.0A GB9712298D0 (en) | 1997-06-12 | 1997-06-12 | Crystallisation |
| PCT/GB1997/003418 WO1998025902A1 (en) | 1996-12-13 | 1997-12-11 | The preparation of enantiomerically-enriched threo-methylphenidate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU7847098A true AU7847098A (en) | 1998-07-03 |
Family
ID=26310627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU78470/98A Abandoned AU7847098A (en) | 1996-12-13 | 1997-12-11 | The preparation of enantiomerically-enriched threo- methylphenidate |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0948484A1 (en) |
| JP (1) | JP2001506621A (en) |
| AU (1) | AU7847098A (en) |
| CA (1) | CA2272373A1 (en) |
| CZ (1) | CZ206299A3 (en) |
| HU (1) | HUP0001604A3 (en) |
| NO (1) | NO992875L (en) |
| PL (1) | PL334136A1 (en) |
| WO (1) | WO1998025902A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6486177B2 (en) | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| US6100401A (en) * | 1998-04-20 | 2000-08-08 | Novartris Ag | Process for preparing the d-threo isomer of methylphenidate hydrochloride |
| US6162919A (en) * | 1998-12-03 | 2000-12-19 | Novartis Ag | Process for preparing the d-threo isomer of methylphenidate hydrochloride |
| US6127385A (en) * | 1999-03-04 | 2000-10-03 | Pharmaquest Limited | Method of treating depression using l-threo-methylphenidate |
| US6395752B1 (en) * | 1999-03-04 | 2002-05-28 | Pharmaquest Limited | Method of treating depression using 1-threo-methylphenidate |
| US6025502A (en) * | 1999-03-19 | 2000-02-15 | The Trustees Of The University Of Pennsylvania | Enantopselective synthesis of methyl phenidate |
| US6221883B1 (en) * | 2000-04-12 | 2001-04-24 | Ross Baldessarini | Method of dopamine inhibition using l-threo-methylphenidate |
| DE60027282T2 (en) * | 2000-06-17 | 2007-04-12 | Pharmaquest Ltd., Hamilton | Use of l-threo-methylphenidate for the manufacture of a medicament for the treatment of depression |
| WO2004080959A2 (en) * | 2003-03-07 | 2004-09-23 | Isp Investments Inc. | Process for the preparation of dexmethylphenidate hydrochloride |
| US7897777B2 (en) | 2007-01-05 | 2011-03-01 | Archimica, Inc. | Process of enantiomeric resolution of D,L-(±)-threo-methylphenidate |
| WO2010128517A1 (en) | 2009-05-07 | 2010-11-11 | Malladi Drugs & Pharmaceuticals Ltd. | Improved process for the preparation of d-threo-ritalinic acid hydrochloride by resolution of dl-threo-ritalinic acid using chiral carboxylic acid |
| JP5886869B2 (en) | 2010-12-17 | 2016-03-16 | ローズ テクノロジーズ | Low temperature synthesis of methylphenidate hydrochloride |
| EP4011364B1 (en) | 2011-03-23 | 2023-12-13 | Ironshore Pharmaceuticals & Development, Inc. | Methods and compositions for treatment of attention deficit disorder |
| US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
| US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US9233924B2 (en) | 2014-03-11 | 2016-01-12 | Ampac Fine Chemicals Llc | Methods for preparing D-threo methylphenidate using diazomethane, and compositions thereof |
| US10081597B2 (en) | 2014-06-27 | 2018-09-25 | Embio Limited | Process for preparation of dexmethylphenidate hydrochloride |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02190195A (en) * | 1989-01-19 | 1990-07-26 | Rikagaku Kenkyusho | Production of optically active propionic acid ester compound |
| JPH02273196A (en) * | 1989-03-08 | 1990-11-07 | Wisconsin Alumni Res Found | Method for improving enantio-selectivity in biocatalytic resolution of racemic compound |
| JP3431204B2 (en) * | 1993-04-22 | 2003-07-28 | 塩野義製薬株式会社 | Norbornane type ester hydrolase |
| BE1007297A3 (en) * | 1993-07-19 | 1995-05-09 | Dsm Nv | OPTICAL METHOD FOR THE PREPARATION OF ACTIVE alcohols and esters, alcohols and esters APPLIED AND WILLING TO SUCH METHODS. |
| DE4420751A1 (en) * | 1994-06-15 | 1995-12-21 | Basf Ag | Process for the preparation of enantiomerically pure lactams |
-
1997
- 1997-12-11 CA CA002272373A patent/CA2272373A1/en not_active Abandoned
- 1997-12-11 JP JP52637898A patent/JP2001506621A/en active Pending
- 1997-12-11 EP EP97949034A patent/EP0948484A1/en not_active Withdrawn
- 1997-12-11 AU AU78470/98A patent/AU7847098A/en not_active Abandoned
- 1997-12-11 PL PL97334136A patent/PL334136A1/en unknown
- 1997-12-11 HU HU0001604A patent/HUP0001604A3/en unknown
- 1997-12-11 CZ CZ992062A patent/CZ206299A3/en unknown
- 1997-12-11 WO PCT/GB1997/003418 patent/WO1998025902A1/en not_active Application Discontinuation
-
1999
- 1999-06-11 NO NO992875A patent/NO992875L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO992875L (en) | 1999-06-14 |
| NO992875D0 (en) | 1999-06-11 |
| CA2272373A1 (en) | 1998-06-18 |
| HUP0001604A2 (en) | 2000-10-28 |
| PL334136A1 (en) | 2000-02-14 |
| JP2001506621A (en) | 2001-05-22 |
| WO1998025902A1 (en) | 1998-06-18 |
| HUP0001604A3 (en) | 2003-03-28 |
| CZ206299A3 (en) | 1999-09-15 |
| EP0948484A1 (en) | 1999-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU7847098A (en) | The preparation of enantiomerically-enriched threo- methylphenidate | |
| AU5703398A (en) | Novel compounds | |
| AU4925697A (en) | Compounds | |
| AU8758298A (en) | Process for the preparation of 2'-fluoro-5-methyl-beta -l-arabinofuranosyluridine | |
| AU2651197A (en) | Processes for the preparation of pyrimidine compound | |
| AU5423298A (en) | Novel compounds | |
| CY2590B2 (en) | Preparation of 1-butyl-4-piperidinylmethylamine | |
| AUPO062696A0 (en) | Novel compounds | |
| AU3783097A (en) | Process for the preparation of hexanitrohexaazaisowurtzitanes | |
| AU3711697A (en) | Novel compounds | |
| AU8102498A (en) | Preparation of diaryl-benzopyrans | |
| AU1207497A (en) | Process for the preparation of para-fluorophenol | |
| AU5330198A (en) | Therapeutic compounds | |
| AU3040797A (en) | Preparation of alpha-fluoroketones | |
| AU4208397A (en) | Process for the preparation of nizatidine | |
| AU4641497A (en) | Novel compounds | |
| AU6887198A (en) | Improved method for the preparation of benzyluracils | |
| AU3705597A (en) | Preparation of aminomethyl-phenylimidazoles | |
| AU5346298A (en) | Method for the preparation of melamine | |
| ZA9711206B (en) | The preparation of enantiomerically-enriched threo-methyl-phenidate | |
| AU4885397A (en) | Aids therapeutic composition | |
| AUPO282996A0 (en) | Novel compounds | |
| AUPO282896A0 (en) | Novel compounds | |
| AU5120798A (en) | Process for the preparation of phtalides | |
| EP0794166A3 (en) | Method for the preparation of hydroxymethylcyclopropane |