NO990832D0 - Syntese av bisendolylmalimider - Google Patents

Syntese av bisendolylmalimider

Info

Publication number
NO990832D0
NO990832D0 NO990832A NO990832A NO990832D0 NO 990832 D0 NO990832 D0 NO 990832D0 NO 990832 A NO990832 A NO 990832A NO 990832 A NO990832 A NO 990832A NO 990832 D0 NO990832 D0 NO 990832D0
Authority
NO
Norway
Prior art keywords
bisendolylmalimides
synthesis
Prior art date
Application number
NO990832A
Other languages
English (en)
Other versions
NO990832L (no
Inventor
Mary Margaret Faul
Jr Leonard L Winneroski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO990832D0 publication Critical patent/NO990832D0/no
Publication of NO990832L publication Critical patent/NO990832L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C07D207/408Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
NO990832A 1996-08-23 1999-02-22 Syntese av bis-endolylmaleimider NO990832L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2412096P 1996-08-23 1996-08-23
PCT/US1997/014771 WO1998007693A1 (en) 1996-08-23 1997-08-22 Synthesis of bisindolylmalimides

Publications (2)

Publication Number Publication Date
NO990832D0 true NO990832D0 (no) 1999-02-22
NO990832L NO990832L (no) 1999-04-13

Family

ID=21818966

Family Applications (1)

Application Number Title Priority Date Filing Date
NO990832A NO990832L (no) 1996-08-23 1999-02-22 Syntese av bis-endolylmaleimider

Country Status (16)

Country Link
US (2) US5990319A (no)
EP (1) EP0825190A1 (no)
JP (1) JP2000516632A (no)
KR (1) KR20000068323A (no)
CN (1) CN1228082A (no)
AU (1) AU716840B2 (no)
BR (1) BR9711363A (no)
CA (1) CA2263862A1 (no)
EA (1) EA001392B1 (no)
HU (1) HUP0003203A3 (no)
IL (1) IL128376A0 (no)
NO (1) NO990832L (no)
NZ (1) NZ334030A (no)
PL (1) PL331899A1 (no)
WO (1) WO1998007693A1 (no)
YU (1) YU9499A (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR017200A1 (es) 1997-12-23 2001-08-22 Astrazeneca Ab Compuestos inhibidores de la proteina cinasa c, sales farmaceuticamente aceptables de los mismos, formulaciones farmaceuitcas que los comprenden, usode las mismas y proceso para la sintesis de dichos compuestos
SE9800835D0 (sv) 1998-03-13 1998-03-13 Astra Ab New Compounds
US6492406B1 (en) 1999-05-21 2002-12-10 Astrazeneca Ab Pharmaceutically active compounds
CA2599611C (en) 2005-02-09 2013-07-30 Chiang J. Li Meleimide derivatives, pharmaceutical compositions and methods for treatment of cancer
CN101801961B (zh) 2007-06-22 2014-09-24 艾科尔公司 吡咯烷酮、吡咯烷-2,5-二酮、吡咯烷和硫代琥珀酰亚胺衍生物、组合物以及治疗癌症的方法
KR20100024494A (ko) 2007-06-22 2010-03-05 아르퀼 인코포레이티드 퀴나졸리논 화합물 및 이의 사용 방법
CN101801969B (zh) 2007-06-22 2014-10-29 艾科尔公司 治疗癌症的吲哚基吡咯烷
FR2927075A1 (fr) * 2008-02-04 2009-08-07 Centre Nat Rech Scient Molecules comprenant un squelette bis-(heteroaryl)maleimide, et leur utilisation dans l'inhibition d'enzymes
TW201350483A (zh) * 2012-04-23 2013-12-16 Arqule Inc 高純度吡咯並喹啉基-吡咯-2,5-二酮及吡咯並喹啉基-吡咯啶-2,5-二酮以及彼等之製備方法
CN104496970B (zh) * 2014-12-17 2017-01-11 河南师范大学 3,4-二(3-吲哚)-2,5-二酮-3-吡咯啉亚胺类化合物及其制备方法和应用
CN104710412B (zh) * 2015-03-27 2017-03-22 河南师范大学 具有抗癌活性的3,4‑二(3‑吲哚)‑2,5‑二酮‑1‑吡咯胺硫脲类化合物及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK278989B6 (sk) * 1988-02-10 1998-05-06 F. Hoffmann-La Roche Ag Substituované pyroly, ich použitie na výrobu lieči
GB9123396D0 (en) * 1991-11-04 1991-12-18 Hoffmann La Roche A process for the manufacture of substituted maleimides
US5339712A (en) * 1993-10-25 1994-08-23 Daryoush Keyvani Hand tool having offset work elements
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
US5541347A (en) * 1993-12-07 1996-07-30 Eli Lilly And Company Synthesis of bisindolylmaleimides
US5559228A (en) * 1995-03-30 1996-09-24 Eli Lilly And Company Synthesis of bisindolylmaleimides

Also Published As

Publication number Publication date
JP2000516632A (ja) 2000-12-12
HUP0003203A3 (en) 2002-01-28
EA199900221A1 (ru) 1999-08-26
CA2263862A1 (en) 1998-02-26
CN1228082A (zh) 1999-09-08
US5990319A (en) 1999-11-23
IL128376A0 (en) 2000-01-31
YU9499A (sh) 2000-03-21
EA001392B1 (ru) 2001-02-26
AU4157097A (en) 1998-03-06
KR20000068323A (ko) 2000-11-25
US5948907A (en) 1999-09-07
HUP0003203A2 (hu) 2001-06-28
PL331899A1 (en) 1999-08-16
WO1998007693A1 (en) 1998-02-26
AU716840B2 (en) 2000-03-09
NZ334030A (en) 2000-08-25
BR9711363A (pt) 1999-08-17
NO990832L (no) 1999-04-13
EP0825190A1 (en) 1998-02-25

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application