NO991545L - FremgangsmÕte for fremstilling av liposomer med °kt prosent av innkapslet forbindelse - Google Patents
FremgangsmÕte for fremstilling av liposomer med °kt prosent av innkapslet forbindelseInfo
- Publication number
- NO991545L NO991545L NO991545A NO991545A NO991545L NO 991545 L NO991545 L NO 991545L NO 991545 A NO991545 A NO 991545A NO 991545 A NO991545 A NO 991545A NO 991545 L NO991545 L NO 991545L
- Authority
- NO
- Norway
- Prior art keywords
- liposomes
- percent
- preparation
- weight
- encapsulated compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/723,583 US5997899A (en) | 1996-10-01 | 1996-10-01 | Method for producing liposomes with increased percent of compound encapsulated |
PCT/US1997/017519 WO1998014171A1 (en) | 1996-10-01 | 1997-09-29 | Method for producing liposomes with increased percent of compound encapsulated |
Publications (2)
Publication Number | Publication Date |
---|---|
NO991545D0 NO991545D0 (no) | 1999-03-30 |
NO991545L true NO991545L (no) | 1999-05-31 |
Family
ID=24906863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO991545A NO991545L (no) | 1996-10-01 | 1999-03-30 | FremgangsmÕte for fremstilling av liposomer med °kt prosent av innkapslet forbindelse |
Country Status (9)
Country | Link |
---|---|
US (4) | US5997899A (de) |
EP (1) | EP1005326B1 (de) |
JP (5) | JP3473959B2 (de) |
AU (1) | AU738020B2 (de) |
CA (1) | CA2267416C (de) |
IL (1) | IL129145A0 (de) |
NO (1) | NO991545L (de) |
NZ (1) | NZ334837A (de) |
WO (1) | WO1998014171A1 (de) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2304096C (en) | 1997-09-18 | 2003-09-09 | Skyepharma Inc. | Sustained-release liposomal anesthetic compositions |
NZ504188A (en) * | 1997-11-14 | 2001-10-26 | Skyepharma Inc | Emulsification process for preparing multivesicular liposomes |
US7157098B1 (en) * | 1998-01-06 | 2007-01-02 | Roman Perez-Soler | Gene therapy of tumors using non-viral delivery system |
DE69935435T2 (de) | 1998-08-12 | 2007-12-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Mittels Ammoniumsulfatgradient hergestellte liposomale analgetische Zusammensetzungen |
AU2001258106A1 (en) * | 2000-05-11 | 2001-11-20 | Celator Technologies Inc. | Lipid carrier compositions for improved drug retention |
WO2002090510A2 (en) * | 2001-05-08 | 2002-11-14 | Emory University | Regulating immine responses using dendritic cells |
WO2003015707A2 (en) * | 2001-08-20 | 2003-02-27 | Transave, Inc. | Method for treating lung cancers |
US7125568B2 (en) * | 2001-08-23 | 2006-10-24 | Sung Michael T | Lipophilic drug compositions |
DK1463487T3 (da) * | 2001-12-19 | 2010-08-23 | Res Dev Foundation | Liposomal afgivelse af vitamin-E baserede forbindelser |
US20030236301A1 (en) * | 2001-12-19 | 2003-12-25 | Bob Sanders | Liposomal delivery of vitamin E based compounds |
US9186322B2 (en) | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
AU2003302314A1 (en) * | 2002-08-02 | 2004-07-09 | Transave, Inc. | Platinum aggregates and process for producing the same |
US20070053918A1 (en) * | 2003-05-12 | 2007-03-08 | Novosom Ag | Injectable depots consisting of liposomal aggregates for the delivery of active substances |
ES2426915T3 (es) | 2003-09-10 | 2013-10-25 | Brentwood Equities Ltd. | Diastereoisómeros de 4-ariloxi-3-hidroxipiperidinas |
HUE027483T2 (en) * | 2003-12-23 | 2016-09-28 | Novozymes Bioag As | Procedures and Preparations Providing Agricultural Benefits in Legumes and Non-Legumes |
US20070065522A1 (en) * | 2004-03-18 | 2007-03-22 | Transave, Inc. | Administration of high potency platinum compound formulations by inhalation |
JP2007529546A (ja) * | 2004-03-18 | 2007-10-25 | トランセイブ, インク. | 吸入によるシスプラチンの投与 |
KR101462819B1 (ko) | 2004-05-03 | 2014-11-21 | 헤르메스 바이오사이언스, 인코포레이티드 | 약물 전달에 유용한 리포좀 |
JP2008500397A (ja) * | 2004-05-21 | 2008-01-10 | トランセイブ, インク. | 肺疾患及び前肺疾患状態の治療 |
KR100618033B1 (ko) | 2004-06-21 | 2006-08-30 | 에이엔에이치 케어연구소(주) | 염산독세핀을 유효성분으로 함유하는 아토피 질환 치료용외용제 조성물 |
MX2007004955A (es) * | 2004-11-08 | 2007-06-14 | Transave Inc | Metodo de tratar cancer con formulaciones de compeusto de platino a base de lipido administradas intraperitonealmente. |
CA3054535A1 (en) | 2005-02-18 | 2006-08-24 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
US20070110674A1 (en) * | 2005-07-29 | 2007-05-17 | Yuhong Xu | Sono-active liposomes and lipid particles and use thereof as contrast agents and active-agent delivery systems |
CN1913508B (zh) * | 2005-08-08 | 2010-05-05 | 华为技术有限公司 | 基于正交频分复用的信号调制方法及其调制装置 |
US20070190182A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
CA2661302A1 (en) * | 2006-08-16 | 2008-02-21 | Auspex Pharmaceuticals, Inc. | Preparation and utility of opioid analgesics |
WO2011062132A1 (ja) | 2009-11-20 | 2011-05-26 | コニカミノルタホールディングス株式会社 | W/o/wエマルションの製造方法およびこれを用いたリポソームの製造方法、並びにこれらの方法に用いられる孔膜 |
US9770414B2 (en) | 2010-05-13 | 2017-09-26 | Pacira Pharmaceuticals, Inc. | Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent |
ES2634669T3 (es) | 2011-02-08 | 2017-09-28 | Halozyme, Inc. | Composición y formulación lipídica de una enzima de degradación de hialuronano y uso de la misma para el tratamiento de la hiperplasia benigna de próstata |
RU2678433C2 (ru) | 2012-05-10 | 2019-01-29 | Пейнреформ Лтд. | Депо-составы гидрофобного активного ингредиента и способы их получения |
AU2013202947B2 (en) | 2012-06-13 | 2016-06-02 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
US9717724B2 (en) | 2012-06-13 | 2017-08-01 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies |
CA2883703C (en) | 2012-09-04 | 2021-10-19 | Eleison Pharmaceuticals, Llc | Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin |
CA2902343C (en) | 2013-03-14 | 2022-08-02 | Becton Dickinson France S.A.S. | Injectable morphine formulations |
EP2968729B1 (de) | 2013-03-14 | 2018-08-15 | Fresenius Kabi Deutschland GmbH | Verpackungssystem für sauerstoffempfindliche medikamenten |
US9956195B2 (en) | 2014-01-07 | 2018-05-01 | Nanyang Technological University | Stable liposomal formulations for ocular drug delivery |
HUE043847T2 (hu) | 2014-08-28 | 2019-09-30 | Halozyme Inc | Hialuronán-lebontó enzimmel és egy immun checkpoint inhibitorral végzett kombinációs terápia |
EP3142656B1 (de) * | 2015-01-21 | 2018-10-17 | Pacira Pharmaceuticals, Inc. | Multivesikuläre liposomformulierungen von tranexamsäure |
US11318131B2 (en) | 2015-05-18 | 2022-05-03 | Ipsen Biopharm Ltd. | Nanoliposomal irinotecan for use in treating small cell lung cancer |
CA2992789A1 (en) | 2015-08-20 | 2017-02-23 | Ipsen Biopharm Ltd. | Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment |
JP2018528185A (ja) | 2015-08-21 | 2018-09-27 | イプセン バイオファーム リミティド | リポソーム型イリノテカン及びオキサリプラチンを含む組み合わせ療法を使用して転移性膵臓癌を治療するための方法 |
US10456360B2 (en) | 2015-10-16 | 2019-10-29 | Ipsen Biopharm Ltd. | Stabilizing camptothecin pharmaceutical compositions |
MA46709A (fr) | 2016-11-02 | 2019-09-11 | Ipsen Biopharm Ltd | Traitement du cancer gastrique au moyen de polythérapies comprenant de l'oxaliplatine, du 5-fluoruracile (et de la leucovorine) et de l'irinotécan sous forme liposomale |
WO2019210296A1 (en) * | 2018-04-27 | 2019-10-31 | Karma Biotechnologies | Multi-vesicular liposomes for targeted delivery of drugs and biologics for tissue engineering |
US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH588887A5 (de) * | 1974-07-19 | 1977-06-15 | Battelle Memorial Institute | |
US4897308A (en) * | 1975-06-30 | 1990-01-30 | L'oreal | Compositions comprising aqueous dispersions of lipid spheres |
US4078052A (en) * | 1976-06-30 | 1978-03-07 | The United States Of America As Represented By The Secretary Of Health, Education And Welfare | Large unilamellar vesicles (LUV) and method of preparing same |
US4086257A (en) * | 1976-10-12 | 1978-04-25 | Sears Barry D | Phosphatidyl quaternary ammonium compounds |
CH624011A5 (de) * | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4310506A (en) * | 1979-02-22 | 1982-01-12 | California Institute Of Technology | Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species |
JPS55153713A (en) * | 1979-05-02 | 1980-11-29 | Kureha Chem Ind Co Ltd | Pharmaceutical preparation of ribosome containing active substance |
US4394372A (en) * | 1980-12-22 | 1983-07-19 | The Procter & Gamble Company | Process for making lipid membrane structures |
US4522803A (en) * | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
US4588578A (en) * | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
US4599227A (en) * | 1983-11-07 | 1986-07-08 | Wisconsin Alumni Research Foundation | Injectable pharmaceutical preparation for the induction of multiple follicular growth |
US4610868A (en) * | 1984-03-20 | 1986-09-09 | The Liposome Company, Inc. | Lipid matrix carriers for use in drug delivery systems |
US5077056A (en) * | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
IE58981B1 (en) * | 1985-10-15 | 1993-12-15 | Vestar Inc | Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles |
US5204112A (en) * | 1986-06-16 | 1993-04-20 | The Liposome Company, Inc. | Induction of asymmetry in vesicles |
US4877619A (en) * | 1986-08-25 | 1989-10-31 | Vestar, Inc. | Liposomal vesicles for intraperitoneal administration of therapeutic agents |
US4781871A (en) * | 1986-09-18 | 1988-11-01 | Liposome Technology, Inc. | High-concentration liposome processing method |
US4752425A (en) * | 1986-09-18 | 1988-06-21 | Liposome Technology, Inc. | High-encapsulation liposome processing method |
US4920016A (en) * | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
US5723147A (en) * | 1987-02-23 | 1998-03-03 | Depotech Corporation | Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride |
JP2666345B2 (ja) * | 1987-04-16 | 1997-10-22 | 武田薬品工業株式会社 | リポソーム製剤およびその製造法 |
US4921644A (en) * | 1988-02-29 | 1990-05-01 | Technology Unlimited, Inc. | Mucin directed lipsome |
US5422120A (en) * | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
BE1001869A3 (fr) * | 1988-10-12 | 1990-04-03 | Franz Legros | Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine. |
EP0665743B1 (de) * | 1992-10-14 | 2001-12-12 | The Liposome Company, Inc. | Interdigitation-fusionsliposomen und gels |
WO1994026253A1 (en) * | 1993-05-19 | 1994-11-24 | The Liposome Company, Inc. | Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer |
US5766627A (en) | 1993-11-16 | 1998-06-16 | Depotech | Multivescular liposomes with controlled release of encapsulated biologically active substances |
US5993850A (en) * | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
-
1996
- 1996-10-01 US US08/723,583 patent/US5997899A/en not_active Expired - Lifetime
-
1997
- 1997-09-29 EP EP97945355.2A patent/EP1005326B1/de not_active Expired - Lifetime
- 1997-09-29 WO PCT/US1997/017519 patent/WO1998014171A1/en active Application Filing
- 1997-09-29 CA CA002267416A patent/CA2267416C/en not_active Expired - Lifetime
- 1997-09-29 AU AU46579/97A patent/AU738020B2/en not_active Expired
- 1997-09-29 JP JP51676198A patent/JP3473959B2/ja not_active Expired - Lifetime
- 1997-09-29 IL IL12914597A patent/IL129145A0/xx not_active IP Right Cessation
- 1997-09-29 NZ NZ334837A patent/NZ334837A/xx not_active IP Right Cessation
-
1999
- 1999-03-30 NO NO991545A patent/NO991545L/no unknown
- 1999-11-01 US US09/431,525 patent/US6171613B1/en not_active Expired - Lifetime
- 1999-11-01 US US09/431,523 patent/US6193998B1/en not_active Expired - Lifetime
- 1999-12-06 US US09/454,521 patent/US6241999B1/en not_active Expired - Lifetime
-
2003
- 2003-06-18 JP JP2003173459A patent/JP2003327544A/ja active Pending
- 2003-06-18 JP JP2003173461A patent/JP2003327526A/ja active Pending
- 2003-06-18 JP JP2003173460A patent/JP2003327525A/ja active Pending
-
2008
- 2008-02-21 JP JP2008040588A patent/JP2008163040A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL129145A0 (en) | 2000-02-17 |
US6171613B1 (en) | 2001-01-09 |
WO1998014171A1 (en) | 1998-04-09 |
JP2008163040A (ja) | 2008-07-17 |
CA2267416A1 (en) | 1998-04-09 |
US6193998B1 (en) | 2001-02-27 |
JP2001505549A (ja) | 2001-04-24 |
CA2267416C (en) | 2007-03-27 |
US5997899A (en) | 1999-12-07 |
JP2003327544A (ja) | 2003-11-19 |
EP1005326B1 (de) | 2017-05-17 |
US6241999B1 (en) | 2001-06-05 |
NO991545D0 (no) | 1999-03-30 |
JP2003327525A (ja) | 2003-11-19 |
JP3473959B2 (ja) | 2003-12-08 |
EP1005326A4 (de) | 2006-03-22 |
AU4657997A (en) | 1998-04-24 |
AU738020B2 (en) | 2001-09-06 |
JP2003327526A (ja) | 2003-11-19 |
NZ334837A (en) | 2000-09-29 |
EP1005326A1 (de) | 2000-06-07 |
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