NO990246L - Akryloylsubstituert distamycinderivater, fremgangsmÕte til fremstilling av disse, og deres anvendelse som antitumor- og antivirusmidler - Google Patents
Akryloylsubstituert distamycinderivater, fremgangsmÕte til fremstilling av disse, og deres anvendelse som antitumor- og antivirusmidlerInfo
- Publication number
- NO990246L NO990246L NO990246A NO990246A NO990246L NO 990246 L NO990246 L NO 990246L NO 990246 A NO990246 A NO 990246A NO 990246 A NO990246 A NO 990246A NO 990246 L NO990246 L NO 990246L
- Authority
- NO
- Norway
- Prior art keywords
- antitumor
- preparing
- methods
- antiviral agents
- distamycin derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9615692.2A GB9615692D0 (en) | 1996-07-25 | 1996-07-25 | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
PCT/EP1997/003719 WO1998004524A1 (en) | 1996-07-25 | 1997-07-10 | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO990246L true NO990246L (no) | 1999-01-20 |
NO990246D0 NO990246D0 (no) | 1999-01-20 |
NO310817B1 NO310817B1 (no) | 2001-09-03 |
Family
ID=10797527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19990246A NO310817B1 (no) | 1996-07-25 | 1999-01-20 | Akryloylsubstituert distamycinderivater, fremgangsmåte til fremstilling av disse, deres anvendelse til fremstilling avantitumor- og antivirusmidler samt et farmasöytisk preparatinneholdende disse |
Country Status (27)
Country | Link |
---|---|
US (2) | US6482920B1 (no) |
EP (1) | EP0915845B1 (no) |
JP (1) | JP4312264B2 (no) |
KR (1) | KR100408538B1 (no) |
CN (1) | CN1116281C (no) |
AR (1) | AR007997A1 (no) |
AT (1) | ATE205476T1 (no) |
AU (1) | AU724511B2 (no) |
BR (1) | BR9710717A (no) |
CA (1) | CA2260060C (no) |
DE (1) | DE69706690T2 (no) |
DK (1) | DK0915845T3 (no) |
EA (1) | EA001863B1 (no) |
ES (1) | ES2164366T3 (no) |
GB (1) | GB9615692D0 (no) |
HK (1) | HK1020948A1 (no) |
HU (1) | HU224635B1 (no) |
IL (1) | IL127689A (no) |
MY (1) | MY124103A (no) |
NO (1) | NO310817B1 (no) |
NZ (1) | NZ334082A (no) |
PL (1) | PL199865B1 (no) |
PT (1) | PT915845E (no) |
TW (1) | TW360652B (no) |
UA (1) | UA61922C2 (no) |
WO (1) | WO1998004524A1 (no) |
ZA (1) | ZA976549B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9806689D0 (en) | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
GB9928703D0 (en) * | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
US6559125B1 (en) | 2000-01-28 | 2003-05-06 | California Institute Of Technology | Polyamide-alkylator conjugates and related products and method |
PA8515201A1 (es) * | 2000-04-14 | 2002-10-24 | Agouron Pharma | Compuestos y composiciones antipicornavirales; sus usos farmaceuticos y los materiales para su sintesis |
GB0011059D0 (en) * | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
GB0015444D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
GB0015447D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
GB0017852D0 (en) * | 2000-07-20 | 2000-09-06 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
US6576612B1 (en) | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
GB0029004D0 (en) * | 2000-11-28 | 2001-01-10 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
CA2450628A1 (en) * | 2001-06-13 | 2002-12-19 | Genesoft Pharmaceuticals, Inc. | Benzothiophene compounds having antiinfective activity |
US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
EP1461083B1 (en) * | 2002-01-02 | 2006-03-29 | Pharmacia Italia S.p.A. | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors |
AU2003219102B2 (en) * | 2002-04-02 | 2008-05-08 | Nerviano Medical Sciences S.R.L. | Combined therapy against tumors comprising subtituted acryloyl distamycin derivatives and radiotherapy |
JP6809464B2 (ja) * | 2015-08-06 | 2021-01-06 | 宇部興産株式会社 | 置換グアニジン誘導体 |
GB202114032D0 (en) * | 2021-09-30 | 2021-11-17 | Univ Strathclyde | Antivirals |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE468642B (sv) * | 1985-07-16 | 1993-02-22 | Erba Farmitalia | Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition |
GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
-
1996
- 1996-07-25 GB GBGB9615692.2A patent/GB9615692D0/en active Pending
-
1997
- 1997-07-10 KR KR10-1999-7000409A patent/KR100408538B1/ko not_active IP Right Cessation
- 1997-07-10 HU HU9903253A patent/HU224635B1/hu not_active IP Right Cessation
- 1997-07-10 DE DE69706690T patent/DE69706690T2/de not_active Expired - Lifetime
- 1997-07-10 EA EA199900163A patent/EA001863B1/ru not_active IP Right Cessation
- 1997-07-10 JP JP50842898A patent/JP4312264B2/ja not_active Expired - Fee Related
- 1997-07-10 CN CN97196737A patent/CN1116281C/zh not_active Expired - Fee Related
- 1997-07-10 EP EP97937474A patent/EP0915845B1/en not_active Expired - Lifetime
- 1997-07-10 AT AT97937474T patent/ATE205476T1/de active
- 1997-07-10 PT PT97937474T patent/PT915845E/pt unknown
- 1997-07-10 PL PL331344A patent/PL199865B1/pl unknown
- 1997-07-10 DK DK97937474T patent/DK0915845T3/da active
- 1997-07-10 AU AU40098/97A patent/AU724511B2/en not_active Ceased
- 1997-07-10 CA CA002260060A patent/CA2260060C/en not_active Expired - Fee Related
- 1997-07-10 WO PCT/EP1997/003719 patent/WO1998004524A1/en active IP Right Grant
- 1997-07-10 US US09/147,573 patent/US6482920B1/en not_active Expired - Lifetime
- 1997-07-10 IL IL12768997A patent/IL127689A/xx not_active IP Right Cessation
- 1997-07-10 BR BR9710717A patent/BR9710717A/pt not_active IP Right Cessation
- 1997-07-10 NZ NZ334082A patent/NZ334082A/xx not_active IP Right Cessation
- 1997-07-10 ES ES97937474T patent/ES2164366T3/es not_active Expired - Lifetime
- 1997-07-18 TW TW086110294A patent/TW360652B/zh not_active IP Right Cessation
- 1997-07-23 ZA ZA9706549A patent/ZA976549B/xx unknown
- 1997-07-25 MY MYPI97003389A patent/MY124103A/en unknown
- 1997-07-25 AR ARP970103377A patent/AR007997A1/es active IP Right Grant
- 1997-10-07 UA UA99021068A patent/UA61922C2/uk unknown
-
1999
- 1999-01-20 NO NO19990246A patent/NO310817B1/no not_active IP Right Cessation
- 1999-12-22 HK HK99106034A patent/HK1020948A1/xx not_active IP Right Cessation
-
2002
- 2002-07-17 US US10/196,363 patent/US20030023031A1/en not_active Abandoned
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |