NO990246L - Akryloylsubstituert distamycinderivater, fremgangsmÕte til fremstilling av disse, og deres anvendelse som antitumor- og antivirusmidler - Google Patents
Akryloylsubstituert distamycinderivater, fremgangsmÕte til fremstilling av disse, og deres anvendelse som antitumor- og antivirusmidlerInfo
- Publication number
- NO990246L NO990246L NO990246A NO990246A NO990246L NO 990246 L NO990246 L NO 990246L NO 990246 A NO990246 A NO 990246A NO 990246 A NO990246 A NO 990246A NO 990246 L NO990246 L NO 990246L
- Authority
- NO
- Norway
- Prior art keywords
- antitumor
- preparing
- methods
- antiviral agents
- distamycin derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9615692.2A GB9615692D0 (en) | 1996-07-25 | 1996-07-25 | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
PCT/EP1997/003719 WO1998004524A1 (en) | 1996-07-25 | 1997-07-10 | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO990246D0 NO990246D0 (no) | 1999-01-20 |
NO990246L true NO990246L (no) | 1999-01-20 |
NO310817B1 NO310817B1 (no) | 2001-09-03 |
Family
ID=10797527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19990246A NO310817B1 (no) | 1996-07-25 | 1999-01-20 | Akryloylsubstituert distamycinderivater, fremgangsmåte til fremstilling av disse, deres anvendelse til fremstilling avantitumor- og antivirusmidler samt et farmasöytisk preparatinneholdende disse |
Country Status (27)
Country | Link |
---|---|
US (2) | US6482920B1 (no) |
EP (1) | EP0915845B1 (no) |
JP (1) | JP4312264B2 (no) |
KR (1) | KR100408538B1 (no) |
CN (1) | CN1116281C (no) |
AR (1) | AR007997A1 (no) |
AT (1) | ATE205476T1 (no) |
AU (1) | AU724511B2 (no) |
BR (1) | BR9710717A (no) |
CA (1) | CA2260060C (no) |
DE (1) | DE69706690T2 (no) |
DK (1) | DK0915845T3 (no) |
EA (1) | EA001863B1 (no) |
ES (1) | ES2164366T3 (no) |
GB (1) | GB9615692D0 (no) |
HK (1) | HK1020948A1 (no) |
HU (1) | HU224635B1 (no) |
IL (1) | IL127689A (no) |
MY (1) | MY124103A (no) |
NO (1) | NO310817B1 (no) |
NZ (1) | NZ334082A (no) |
PL (1) | PL199865B1 (no) |
PT (1) | PT915845E (no) |
TW (1) | TW360652B (no) |
UA (1) | UA61922C2 (no) |
WO (1) | WO1998004524A1 (no) |
ZA (1) | ZA976549B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9806689D0 (en) | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
GB9928703D0 (en) * | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
US6559125B1 (en) | 2000-01-28 | 2003-05-06 | California Institute Of Technology | Polyamide-alkylator conjugates and related products and method |
PA8515201A1 (es) * | 2000-04-14 | 2002-10-24 | Agouron Pharma | Compuestos y composiciones antipicornavirales; sus usos farmaceuticos y los materiales para su sintesis |
GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
GB0015444D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
GB0015447D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
GB0015446D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
GB0017852D0 (en) * | 2000-07-20 | 2000-09-06 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
US6576612B1 (en) | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
GB0029004D0 (en) * | 2000-11-28 | 2001-01-10 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
JP2005505508A (ja) * | 2001-06-13 | 2005-02-24 | ジーンソフト ファーマシューティカルズ インコーポレイテッド | 抗感染活性を有するベンゾチオフェン化合物 |
US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
BR0215454A (pt) * | 2002-01-02 | 2004-11-23 | Pharmacia Italia Spa | Terapia combinada contra tumores, comprendendo derivados de acriloil-distamicina substituìdos e inibidores de proteìna cinase (serina/treonina cinase) |
ATE383154T1 (de) * | 2002-04-02 | 2008-01-15 | Nerviano Medical Sciences Srl | Kombinierte tumortherapie auf der basis von distamycin-acryloyl derivaten und radiotherapie |
RU2733951C9 (ru) * | 2015-08-06 | 2020-12-22 | Убе Индастриз, Лтд. | Замещенные производные гуанидина |
GB202114032D0 (en) * | 2021-09-30 | 2021-11-17 | Univ Strathclyde | Antivirals |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT387013B (de) * | 1985-07-16 | 1988-11-25 | Erba Farmitalia | Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten |
GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
-
1996
- 1996-07-25 GB GBGB9615692.2A patent/GB9615692D0/en active Pending
-
1997
- 1997-07-10 EP EP97937474A patent/EP0915845B1/en not_active Expired - Lifetime
- 1997-07-10 PT PT97937474T patent/PT915845E/pt unknown
- 1997-07-10 US US09/147,573 patent/US6482920B1/en not_active Expired - Lifetime
- 1997-07-10 EA EA199900163A patent/EA001863B1/ru not_active IP Right Cessation
- 1997-07-10 AU AU40098/97A patent/AU724511B2/en not_active Ceased
- 1997-07-10 DE DE69706690T patent/DE69706690T2/de not_active Expired - Lifetime
- 1997-07-10 WO PCT/EP1997/003719 patent/WO1998004524A1/en active IP Right Grant
- 1997-07-10 BR BR9710717A patent/BR9710717A/pt not_active IP Right Cessation
- 1997-07-10 KR KR10-1999-7000409A patent/KR100408538B1/ko not_active IP Right Cessation
- 1997-07-10 HU HU9903253A patent/HU224635B1/hu not_active IP Right Cessation
- 1997-07-10 ES ES97937474T patent/ES2164366T3/es not_active Expired - Lifetime
- 1997-07-10 DK DK97937474T patent/DK0915845T3/da active
- 1997-07-10 AT AT97937474T patent/ATE205476T1/de active
- 1997-07-10 NZ NZ334082A patent/NZ334082A/xx not_active IP Right Cessation
- 1997-07-10 CN CN97196737A patent/CN1116281C/zh not_active Expired - Fee Related
- 1997-07-10 JP JP50842898A patent/JP4312264B2/ja not_active Expired - Fee Related
- 1997-07-10 PL PL331344A patent/PL199865B1/pl unknown
- 1997-07-10 IL IL12768997A patent/IL127689A/xx not_active IP Right Cessation
- 1997-07-10 CA CA002260060A patent/CA2260060C/en not_active Expired - Fee Related
- 1997-07-18 TW TW086110294A patent/TW360652B/zh not_active IP Right Cessation
- 1997-07-23 ZA ZA9706549A patent/ZA976549B/xx unknown
- 1997-07-25 AR ARP970103377A patent/AR007997A1/es active IP Right Grant
- 1997-07-25 MY MYPI97003389A patent/MY124103A/en unknown
- 1997-10-07 UA UA99021068A patent/UA61922C2/uk unknown
-
1999
- 1999-01-20 NO NO19990246A patent/NO310817B1/no not_active IP Right Cessation
- 1999-12-22 HK HK99106034A patent/HK1020948A1/xx not_active IP Right Cessation
-
2002
- 2002-07-17 US US10/196,363 patent/US20030023031A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |