NO984631L - <alfa>1-Adrenerge reseptor-antagonister - Google Patents

<alfa>1-Adrenerge reseptor-antagonister

Info

Publication number
NO984631L
NO984631L NO984631A NO984631A NO984631L NO 984631 L NO984631 L NO 984631L NO 984631 A NO984631 A NO 984631A NO 984631 A NO984631 A NO 984631A NO 984631 L NO984631 L NO 984631L
Authority
NO
Norway
Prior art keywords
adrenergic receptor
alfa
receptor antagonists
derivatives
treatment
Prior art date
Application number
NO984631A
Other languages
English (en)
Other versions
NO984631D0 (no
Inventor
Dennis Bigg
Pierre-Etienne Cha Lassauniere
Serge Auvin
Michel Auguet
Original Assignee
Sociutu De Conseils De Rech Et
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sociutu De Conseils De Rech Et filed Critical Sociutu De Conseils De Rech Et
Publication of NO984631D0 publication Critical patent/NO984631D0/no
Publication of NO984631L publication Critical patent/NO984631L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)

Abstract

Fenylpiperazinderivater som har en høy affinitet til den a,-adrenerge reseptor og farmasøytiske blandinger inneholdende disse er beskrevet. En metode for anvendelse av slike derivater for behandling av benign prostatisk hyperplasia er også beskrevet.
NO984631A 1996-04-05 1998-10-02 <alfa>1-Adrenerge reseptor-antagonister NO984631L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62827696A 1996-04-05 1996-04-05
PCT/FR1997/000615 WO1997037983A1 (fr) 1996-04-05 1997-04-04 ANTAGONISTES DU RECEPTEUR α1-ADRENERGIQUE

Publications (2)

Publication Number Publication Date
NO984631D0 NO984631D0 (no) 1998-10-02
NO984631L true NO984631L (no) 1998-12-02

Family

ID=24518205

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984631A NO984631L (no) 1996-04-05 1998-10-02 <alfa>1-Adrenerge reseptor-antagonister

Country Status (15)

Country Link
US (1) US6300499B1 (no)
EP (1) EP0891344B1 (no)
JP (1) JP3845452B2 (no)
AT (1) ATE229946T1 (no)
AU (1) AU2393997A (no)
CZ (1) CZ315098A3 (no)
DE (1) DE69717978T2 (no)
DK (1) DK0891344T3 (no)
ES (1) ES2188936T3 (no)
HU (1) HUP9901680A3 (no)
IL (1) IL126411A0 (no)
NO (1) NO984631L (no)
PL (1) PL329190A1 (no)
RU (1) RU2179554C2 (no)
WO (1) WO1997037983A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5661163A (en) 1995-06-07 1997-08-26 Merck & Co., Inc. Alpha-1a adrenergic receptor antagonists
GB9819860D0 (en) 1998-09-12 1998-11-04 Zeneca Ltd Chemical compounds
WO2003084541A1 (en) * 2002-04-08 2003-10-16 Ranbaxy Laboratories Limited Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers
RU2320656C2 (ru) * 2002-07-04 2008-03-27 Шварц Фарма Аг Производные гетероаренкарбоксамида, способ их получения, фармацевтическая композиция на их основе и применение
DE10251170A1 (de) * 2002-10-31 2004-05-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
WO2006021344A1 (en) * 2004-08-27 2006-03-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with alpha-1a adrenergic receptor (adra1a)
US9056817B2 (en) * 2011-09-12 2015-06-16 Council Of Scientific And Industrial Research Arylated β-dicarbonyl compounds and process for the preparation thereof
CN103304486A (zh) * 2013-06-25 2013-09-18 南方医科大学 6-（4-芳基哌嗪-1-基）哒嗪-3（2h）-酮及其应用
CN103288745A (zh) * 2013-06-25 2013-09-11 南方医科大学 一种2,6-二取代哒嗪酮类化合物及其应用
WO2015029447A1 (ja) * 2013-08-30 2015-03-05 興和株式会社 光学活性カルビノール化合物の製造方法
CN115124415A (zh) * 2022-06-20 2022-09-30 西咸新区行易先进材料科技有限公司 一种合成阿卓乳酸的催化反应方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2722529A (en) * 1955-11-01 Amides of certain l-amevoalkyl-x-phenyl
US2833770A (en) * 1958-05-06 Chj-chj
NL8005133A (nl) 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
IL90279A (en) 1988-05-24 1995-03-30 American Home Prod History of piperazinyl carboxamide, their preparation and the pharmaceutical preparations containing them
DK0395313T3 (da) * 1989-04-22 2000-06-19 American Home Prod Tertiære alkyl-funktionaliserede piperazin-derivater
FR2655988B1 (fr) * 1989-12-20 1994-05-20 Adir Cie Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4121276C2 (de) 1991-06-27 1994-02-17 Metallgesellschaft Ag Verfahren zur Herstellung sulfathaltiger, basischer Polyaluminiumchlorid-Lösungen
GB9200293D0 (en) 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives
SE9201138D0 (sv) * 1992-04-09 1992-04-09 Astra Ab Novel phthalimidoalkylpiperazines
US5284990A (en) 1992-07-16 1994-02-08 Stratco, Inc. Method for converting a hydrogen fluoride alkylation unit to a sulfuric acid alkylation unit
US5349844A (en) 1992-09-11 1994-09-27 Trc Companies, Inc. System and method for resonant filter mass monitoring
SE9300295D0 (sv) 1993-01-28 1993-01-28 Benny Carlstroem Foerfarande och anordning foer bindning av tandlagningsmaterial
CA2166100A1 (en) * 1993-06-23 1995-01-05 Richard A. Glennon Sigma receptor ligands and the use thereof
US5414585A (en) 1993-07-19 1995-05-09 Quantum Corp. Rotating tape edge guide
IT1266582B1 (it) * 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
US5696123A (en) * 1994-09-17 1997-12-09 Boehringer Ingelheim Kg Neurokinin antagonists

Also Published As

Publication number Publication date
ES2188936T3 (es) 2003-07-01
EP0891344B1 (fr) 2002-12-18
JP3845452B2 (ja) 2006-11-15
AU2393997A (en) 1997-10-29
CZ315098A3 (cs) 1999-04-14
DK0891344T3 (da) 2003-04-07
NO984631D0 (no) 1998-10-02
JP2000508310A (ja) 2000-07-04
ATE229946T1 (de) 2003-01-15
PL329190A1 (en) 1999-03-15
HUP9901680A3 (en) 2000-12-28
DE69717978T2 (de) 2003-10-02
US6300499B1 (en) 2001-10-09
HUP9901680A2 (hu) 1999-09-28
DE69717978D1 (de) 2003-01-30
IL126411A0 (en) 1999-05-09
EP0891344A1 (fr) 1999-01-20
WO1997037983A1 (fr) 1997-10-16
RU2179554C2 (ru) 2002-02-20

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application