NO984284L - Nye tripeptidforbindelser og anti-AIDS-legemidler - Google Patents

Nye tripeptidforbindelser og anti-AIDS-legemidler

Info

Publication number
NO984284L
NO984284L NO984284A NO984284A NO984284L NO 984284 L NO984284 L NO 984284L NO 984284 A NO984284 A NO 984284A NO 984284 A NO984284 A NO 984284A NO 984284 L NO984284 L NO 984284L
Authority
NO
Norway
Prior art keywords
aids drugs
compounds
tripeptide compounds
new tripeptide
new
Prior art date
Application number
NO984284A
Other languages
English (en)
Norwegian (no)
Other versions
NO984284D0 (no
Inventor
Haruo Takaku
Satoshi Nojima
Tsutomu Mimoto
Keisuke Terashima
Yoshiaki Kiso
Original Assignee
Japan Energy Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Energy Corp filed Critical Japan Energy Corp
Publication of NO984284D0 publication Critical patent/NO984284D0/no
Publication of NO984284L publication Critical patent/NO984284L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO984284A 1996-12-27 1998-09-16 Nye tripeptidforbindelser og anti-AIDS-legemidler NO984284L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP35922696 1996-12-27
JP15052097 1997-05-23
PCT/JP1997/004734 WO1998029118A1 (fr) 1996-12-27 1997-12-22 Nouveaux composes de tripeptides et medicaments anti-sida

Publications (2)

Publication Number Publication Date
NO984284D0 NO984284D0 (no) 1998-09-16
NO984284L true NO984284L (no) 1999-08-26

Family

ID=26480090

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984284A NO984284L (no) 1996-12-27 1998-09-16 Nye tripeptidforbindelser og anti-AIDS-legemidler

Country Status (5)

Country Link
US (1) US6291432B1 (de)
EP (1) EP0900566A4 (de)
CA (1) CA2249747A1 (de)
NO (1) NO984284L (de)
WO (1) WO1998029118A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
US6593455B2 (en) 2001-08-24 2003-07-15 Tripep Ab Tripeptide amides that block viral infectivity and methods of use thereof
US6455670B1 (en) 2001-09-06 2002-09-24 Tripep Ab Pentamer peptide amide, ALGPG-NH2, that inhibits viral infectivity and methods of use thereof
WO2003024995A1 (en) 2001-09-19 2003-03-27 Tripep Ab Molecules that block viral infectivity and methods of use thereof
KR101368988B1 (ko) 2005-09-16 2014-02-28 다케다 야쿠힌 고교 가부시키가이샤 디펩티딜 펩티다제 억제제
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0395664A1 (de) 1987-10-21 1990-11-07 The Upjohn Company Renin-inhibitoren, die einen (1-amino-2-hydroxy-2-heterocyclus)-ethyl-baustein enthalten
US4963655A (en) 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
US5342922A (en) 1989-03-08 1994-08-30 Washington University Inhibitors of retroviral protease
US5086165A (en) 1989-03-08 1992-02-04 Washington University Inhibitors of retroviral protease with a ketomethylene isosteric replaced amide bond
DE3913272A1 (de) 1989-04-22 1990-10-25 Hoechst Ag Dipeptid-derivate mit enzym-inhibitorischer wirkung
US5126326A (en) 1989-06-06 1992-06-30 Bio-Mega, Inc. Enzyme inhibiting peptide derivatives
US5212157A (en) 1989-06-06 1993-05-18 Bio-Mega, Inc. Enzyme inhibitors
DE4001236A1 (de) 1990-01-18 1991-07-25 Bayer Ag Neue peptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel, insbesondere als arzneimittel gegen retroviren
EP0438311A3 (en) 1990-01-19 1992-07-01 Merck & Co. Inc. Di- and tripeptide renin inhibitors
EP0546115A1 (de) 1990-08-24 1993-06-16 The Upjohn Company Peptide mit aminopolyolen als übergangszustandsimitatoren
US5192668A (en) 1990-10-11 1993-03-09 Merck & Co., Inc. Synthesis of protease inhibitor
US5188950A (en) 1990-10-11 1993-02-23 Merck & Co., Inc. Method of preparing HIV protease inhibitors
US5187074A (en) 1990-10-11 1993-02-16 Merck & Co., Inc. Method of hydroxylation with ATCC 55086
JPH05294993A (ja) 1990-10-22 1993-11-09 Takeda Chem Ind Ltd レトロウイルスプロテアーゼ阻害物質
US5475013A (en) 1990-11-19 1995-12-12 Monsanto Company Retroviral protease inhibitors
EP0559793A1 (de) 1990-11-30 1993-09-15 Smithkline Beecham Corporation Hiv-protease inhibitoren
CA2056911C (en) * 1990-12-11 1998-09-22 Yuuichi Nagano Hiv protease inhibitors
IL100899A (en) 1991-02-08 1997-06-10 Sankyo Co Beta-amino-alpha- hydroxycarboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IE922316A1 (en) 1991-07-17 1993-01-27 Smithkline Beecham Corp Retroviral protease inhibitors
JPH05178824A (ja) 1991-08-05 1993-07-20 Takeda Chem Ind Ltd アスパラギン誘導体およびその用途
WO1993008184A1 (en) 1991-10-23 1993-04-29 Merck & Co., Inc. Hiv protease inhibitors
ZA929869B (en) * 1991-12-20 1994-06-20 Syntex Inc Hiv protease inhibitors
US5644028A (en) 1992-05-13 1997-07-01 Japan Energy Corporation Process for producing peptide derivatives and salts therefor
ZA935697B (en) 1992-08-07 1994-03-10 Sankyo Co Peptides capable of inhibiting the activity of hiv protease their preparation and their therapeutic use
JPH06100533A (ja) * 1992-08-07 1994-04-12 Sankyo Co Ltd Ｈｉｖプロテアーゼ阻害活性を有するペプチド誘導体
US5434265A (en) 1992-12-22 1995-07-18 Eli Lilly And Company Inhibitors of HIV protease
US5554653A (en) 1992-12-22 1996-09-10 Eli Lilly And Company Inhibitors of HIV protease useful for the treatment of AIDS
ES2150933T3 (es) 1992-12-22 2000-12-16 Lilly Co Eli Inhibidores de la proteasa vih utiles para el tratamiento del sida.
US5491166A (en) 1992-12-22 1996-02-13 Eli Lilly And Company Inhibitors of HIV protease useful for the treatment of AIDS
MX9308016A (es) 1992-12-22 1994-08-31 Lilly Co Eli Compuestos inhibidores de la proteasa del virus de la inmunodeficiencia humana, procedimiento para su preparacion y formulacion farmaceutica que los contiene.
JPH06220031A (ja) * 1993-01-25 1994-08-09 Japan Energy Corp ペプチド誘導体またはその塩の製造法
AU6135294A (en) 1993-02-12 1994-08-29 Merck & Co., Inc. Piperazine derivatives as hiv protease inhibitors
AU6828894A (en) 1993-05-14 1994-12-12 Merck & Co., Inc. Hiv protease inhibitors
US5587514A (en) 1993-11-08 1996-12-24 Emory University Diastereoselective synthesis of hydroxyethylene dipeptide isosteres
US5476874A (en) 1994-06-22 1995-12-19 Merck & Co., Inc. New HIV protease inhibitors
US5492910A (en) 1994-11-17 1996-02-20 Bristol-Myers Squibb Co. Retrocarbamate protease inhibitors
WO1996028423A1 (fr) 1995-03-15 1996-09-19 Sankyo Company, Limited Composes dipeptidiques de structure ahpba
JP3408379B2 (ja) * 1995-06-30 2003-05-19 株式会社ジャパンエナジー 新規なジペプチド化合物又はその薬理的に許容される塩及びその医薬用途

Also Published As

Publication number Publication date
CA2249747A1 (en) 1998-07-09
EP0900566A1 (de) 1999-03-10
NO984284D0 (no) 1998-09-16
AU7888598A (en) 1998-07-31
WO1998029118A1 (fr) 1998-07-09
US6291432B1 (en) 2001-09-18
EP0900566A4 (de) 2001-04-25
AU721578B2 (en) 2000-07-06

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