AU6135294A - Piperazine derivatives as hiv protease inhibitors - Google Patents

Piperazine derivatives as hiv protease inhibitors

Info

Publication number
AU6135294A
AU6135294A AU61352/94A AU6135294A AU6135294A AU 6135294 A AU6135294 A AU 6135294A AU 61352/94 A AU61352/94 A AU 61352/94A AU 6135294 A AU6135294 A AU 6135294A AU 6135294 A AU6135294 A AU 6135294A
Authority
AU
Australia
Prior art keywords
protease inhibitors
hiv protease
piperazine derivatives
piperazine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61352/94A
Inventor
Arun K. Ghosh
James P. Guare
Joel R. Huff
Randall W. Hungate
Byeong Moon Kim
Hee Yoon Lee
Wayne J. Thompson
Joseph P. Vacca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU6135294A publication Critical patent/AU6135294A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU61352/94A 1993-02-12 1994-02-07 Piperazine derivatives as hiv protease inhibitors Abandoned AU6135294A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1709093A 1993-02-12 1993-02-12
US017090 1994-01-04
PCT/US1994/001370 WO1994018192A1 (en) 1993-02-12 1994-02-07 Piperazine derivatives as hiv protease inhibitors

Publications (1)

Publication Number Publication Date
AU6135294A true AU6135294A (en) 1994-08-29

Family

ID=21780667

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61352/94A Abandoned AU6135294A (en) 1993-02-12 1994-02-07 Piperazine derivatives as hiv protease inhibitors

Country Status (2)

Country Link
AU (1) AU6135294A (en)
WO (1) WO1994018192A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114316B2 (en) 2004-08-21 2012-02-14 Merck Patent Gmbh Monomers, oligomers and polymers of thieno[2,3-b]thiophene

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878728B1 (en) 1999-06-11 2005-04-12 Vertex Pharmaceutical Incorporated Inhibitors of aspartyl protease
US20040122000A1 (en) 1981-01-07 2004-06-24 Vertex Pharmaceuticals Incorporated. Inhibitors of aspartyl protease
US5723490A (en) * 1992-09-08 1998-03-03 Vertex Pharmaceuticals Incorporated THF-containing sulfonamide inhibitors of aspartyl protease
IS2334B (en) * 1992-09-08 2008-02-15 Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) Aspartyl protease inhibitor of a new class of sulfonamides
US5783701A (en) * 1992-09-08 1998-07-21 Vertex Pharmaceuticals, Incorporated Sulfonamide inhibitors of aspartyl protease
DE69512220T2 (en) * 1994-03-07 2000-03-16 Vertex Pharmaceuticals Inc. SULPHONAMIDE DERIVATIVES AS ASPARTYL PROTEASE INHIBITORS
GB2292146A (en) * 1994-08-11 1996-02-14 Merck & Co Inc HIV protease inhibitors useful for the treatment of AIDS
DK0710652T3 (en) * 1994-11-04 1998-09-28 Yamakawa Chemical Ind Process for the preparation of optically active piperazine derivatives and intermediates for the preparation
US5691372A (en) * 1995-04-19 1997-11-25 Vertex Pharmaceuticals Incorporated Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease
US6004957A (en) * 1995-06-07 1999-12-21 Vertex Pharmaceuticals, Incorporated Sulfonamide inhibitors of aspartyl protease
US6222043B1 (en) 1995-06-30 2001-04-24 Japan Energy Corporation Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof
US5932550A (en) * 1995-06-30 1999-08-03 Japan Energy Corporation Dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
US5905068A (en) * 1996-09-24 1999-05-18 Abbott Laboratories Retroviral protease inhibiting compounds
EP0900566A4 (en) 1996-12-27 2001-04-25 Japan Energy Corp Novel tripeptide compounds and anti-aids drugs
US6436989B1 (en) 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
DK1086076T3 (en) 1998-06-19 2005-03-29 Vertex Pharma Sulfonamide inhibitors of aspartyl protease
US6689765B2 (en) 1999-05-04 2004-02-10 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
US6391865B1 (en) 1999-05-04 2002-05-21 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
CN100519554C (en) 2001-03-29 2009-07-29 先灵公司 CCR5 antagonists for treating aids
EP2614055A2 (en) 2010-09-10 2013-07-17 Lupin Limited Process for preparation of substantially pure fosamprenavir calcium and its intermediates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
US5164388A (en) * 1988-10-19 1992-11-17 Abbott Laboratories Heterocyclic peptide renin inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114316B2 (en) 2004-08-21 2012-02-14 Merck Patent Gmbh Monomers, oligomers and polymers of thieno[2,3-b]thiophene

Also Published As

Publication number Publication date
WO1994018192A1 (en) 1994-08-18

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