NO983332L - Gassboblesuspensjoner og deres anvendelse som ultralydkontrastmiddel - Google Patents

Gassboblesuspensjoner og deres anvendelse som ultralydkontrastmiddel

Info

Publication number
NO983332L
NO983332L NO983332A NO983332A NO983332L NO 983332 L NO983332 L NO 983332L NO 983332 A NO983332 A NO 983332A NO 983332 A NO983332 A NO 983332A NO 983332 L NO983332 L NO 983332L
Authority
NO
Norway
Prior art keywords
contrast agent
gas bubble
ultrasonic contrast
bubble suspensions
suspensions
Prior art date
Application number
NO983332A
Other languages
English (en)
Other versions
NO983332D0 (no
Inventor
Martina Bergmann
Dieter Heldmann
Werner Weitschies
Thomas Fritzsch
Violetta Sudmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO983332D0 publication Critical patent/NO983332D0/no
Publication of NO983332L publication Critical patent/NO983332L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
    • C08J9/12—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
    • C08J9/14—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
    • C08J9/143—Halogen containing compounds
    • C08J9/147—Halogen containing compounds containing carbon and halogen atoms only
    • C08J9/148—Halogen containing compounds containing carbon and halogen atoms only perfluorinated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
    • C08J9/12—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
    • C08J9/14—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
    • C08J9/143—Halogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00—Characterised by the use of unspecified polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Oppfinnelsen angår porøse matrikser av lavmolekylære substanser for dannelse av stabile gassboblesuspensjoner, deres anvendelse som ultralydkontrastmiddel og fremgangsmåte for fremstilling av matrikser og middel.
NO983332A 1996-01-18 1998-07-17 Gassboblesuspensjoner og deres anvendelse som ultralydkontrastmiddel NO983332L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19602930A DE19602930A1 (de) 1996-01-18 1996-01-18 Poröse Matrices aus niedermolekularen Substanzen zur Genierung stabiler Gasblasensuspensionen, deren Verwendung als Ultraschallkontrastmittel sowie Verfahren zu deren Herstellung
PCT/EP1997/000208 WO1997026016A2 (de) 1996-01-18 1997-01-16 Gasblasensuspensionen und deren verwendung als ultraschallkontrastmittel

Publications (2)

Publication Number Publication Date
NO983332D0 NO983332D0 (no) 1998-07-17
NO983332L true NO983332L (no) 1998-07-17

Family

ID=7783852

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983332A NO983332L (no) 1996-01-18 1998-07-17 Gassboblesuspensjoner og deres anvendelse som ultralydkontrastmiddel

Country Status (8)

Country Link
EP (1) EP0874644A2 (no)
JP (1) JP2000504317A (no)
AU (1) AU1592597A (no)
CA (1) CA2243174A1 (no)
DE (1) DE19602930A1 (no)
NO (1) NO983332L (no)
WO (1) WO1997026016A2 (no)
ZA (1) ZA97414B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2473665T3 (es) * 2005-11-28 2014-07-07 Verrow Pharmaceuticals, Inc. Composiciones útiles para reducir la nefrotoxicidad y los métodos de uso de las mismas
JP5196896B2 (ja) * 2007-07-13 2013-05-15 花王株式会社 微細気泡前駆体の製造方法
JP2010005512A (ja) * 2008-06-25 2010-01-14 Kao Corp 微細気泡前駆体組成物
KR101927614B1 (ko) 2017-03-30 2018-12-10 숭실대학교산학협력단 초음파 영상을 위한 안정한 생체적합 산소-나노버블 조영제 제조방법
JP7211699B2 (ja) * 2017-09-11 2023-01-24 バイエル ファーマ アクチエンゲゼルシャフト 超音波診断用造影剤

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung
DE3313946A1 (de) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3313947A1 (de) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3834705A1 (de) * 1988-10-07 1990-04-12 Schering Ag Ultraschallkontrastmittel aus gasblaeschen und fettsaeure enthaltenden mikropartikeln
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US5147631A (en) * 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
US5558857A (en) * 1991-06-03 1996-09-24 Nycomed Imaging As Contrast agents
JPH06510758A (ja) * 1991-07-05 1994-12-01 ニユコメド・イメージング・アクシエセルカペト 造影剤におけるまたは造影剤に関する改良
JPH06511481A (ja) * 1991-07-05 1994-12-22 ユニバーシティ オブ ロチェスター 気泡を取り込む超微小非凝集多孔質粒子
CA2119129C (en) * 1991-09-17 1999-11-09 Steven C. Quay Gaseous ultrasound contrast media and method for selecting gases for use as ultrasound contrast media
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) * 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
AU694135B2 (en) * 1993-07-30 1998-07-16 Imcor Pharmaceutical Company Stabilized microbubble compositions for ultrasound
JPH10508284A (ja) * 1993-12-15 1998-08-18 ブラッコ リサーチ ソシエテ アノニム 超音波造影媒体、この媒体を含む造影剤及び方法
GB9402867D0 (en) * 1994-02-15 1994-04-06 Nycomed Imaging As Improvements in or relating to contrast agents
DE4406474A1 (de) * 1994-02-23 1995-08-24 Schering Ag Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel

Also Published As

Publication number Publication date
JP2000504317A (ja) 2000-04-11
CA2243174A1 (en) 1997-07-24
EP0874644A2 (de) 1998-11-04
ZA97414B (en) 1997-07-17
WO1997026016A2 (de) 1997-07-24
NO983332D0 (no) 1998-07-17
AU1592597A (en) 1997-08-11
DE19602930A1 (de) 1997-07-24
WO1997026016A3 (de) 1997-10-23

Similar Documents

Publication Publication Date Title
NO20030374L (no) Syklopentanoindoler, preparater som inneholder slike forbindelser og behandlingsfremgangsmåter
CY1106008T1 (el) Συνθεσεις που σχηματιζουν μεμβρανη που πepιλαμβανουν τροποποιημενα αμυλα και γιωτα-καρραγενανη και μεθοδοι δια την παρασκευη μαλακων καψουλων δια χρησιμοποιησεως αυτων
DK1100344T3 (da) Chitosanholdige flydende præparater og fremgangsmåder til deres fremstilling og anvendelse
CY1107319T1 (el) Μεθοδος για τον καθαρισμο βακτηριακων κυτταρων και κυτταρικων συστατικων
DK1076657T3 (da) Hidtil ukendte hydroxyindoler, deres anvendelse som inhibitorer for phosphodiesterase 4 og fremgangsmåde til deres fremstilling
TR200000782T2 (tr) Resorsinol türevleri.
DE69717537D1 (de) 6-Benzyl-2H-pyridazin-3-on Derivate,deren Herstellung und deren Verwendung als Inhibitoren der Prostaglandin G/H Synthase I and II (COX I and COX II)
DK0922045T3 (da) Bicykliske pyrimidinderivater og deres anvendelse som antikoagulanter
DE69514661T2 (de) Polymerisationskatalysatorsystem, ihre herstellung und gebrauch
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
NO20012977D0 (no) N-ureidoalkylpiperidiner som modulatorer av chemokinreseptoraktivitet
DE60035032D1 (de) Verwendung von pioglitazone zur verbesserung der ketose und der azidose
DE69901433D1 (de) Homogene und stabile suspension ohne emulgiermittel,verfahren zu ihrer herstellung und ihre verwendung in nahrungsmittelzusammnensetzungen
ID30238A (id) Komposisi-komposisi amifostin amorf yang stabil dan metode-metode untuk pembuatan dan penggunaannya
DK1097173T3 (da) Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler
BR0115354A (pt) Composições de suspensão de lìquidos estáveis, método de preparo e uso das mesmas
NO983332L (no) Gassboblesuspensjoner og deres anvendelse som ultralydkontrastmiddel
BRPI0507987A (pt) métodos e compostos moduladores receptor de glicocorticóide
NO20044446L (no) Anvendelse av polymerer omfattende termoplastiske polymerer som filterhjelpemidler og/eller stabiliseringsmiddel
MX9101958A (es) Inhibidores de acat de urea de aminosulfonilo
ECSP034530A (es) Derivados de 6-metil-tramadol sustituido en o
DK0678096T3 (da) Syntese af dimerblokke og deres anvendelse til aggregering af oligonukleotider
IT1278056B1 (it) Derivati della s-triazina, loro preparazione e loro impiego come assorbenti uv.
DK1085920T3 (da) Dextrinholdigt præparat til forebyggelse af kirurgiske adhæsioner
NO882030D0 (no) Fremgangsmaate til fremstilling av hydrasinderivater til bruk som antihypertensivt middel.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application